Showing entry for L-xylulose reductase



                       
General Target Information
BXGT IdBXGT017257
Protein NameL-xylulose reductase
Uniport IdQ7Z4W1
GeneDCXR
Gene Id51181
Domainadh_short_C2
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00040 Pentose and glucuronate interconversions
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042732 D-xylose metabolic process
Biological Process GO:0006006 glucose metabolic process
Biological Process GO:0019640 glucuronate catabolic process to xylulose 5-phosphate
Biological Process GO:0006739 NADP metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0005997 xylulose metabolic process
molecular function GO:0004090 carbonyl reductase (NADPH) activity
molecular function GO:0042802 identical protein binding
molecular function GO:0044105 L-xylulose reductase (NAD+) activity
molecular function GO:0050038 L-xylulose reductase (NADP+) activity
molecular function GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
cellular component GO:0005903 brush border
cellular component GO:0005881 cytoplasmic microtubule
cellular component GO:0070062 extracellular exosome
cellular component GO:0005902 microvillus
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-5661270 Formation of xylulose-5-phosphate
R-HSA-5662853 Essential pentosuria
R-HSA-5663084 Diseases of carbohydrate metabolism
R-HSA-5668914 Diseases of metabolism
R-HSA-71387 Metabolism of carbohydrates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0008533 BXGD000556 Hemophilia B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0016059 BXGD001043 Fibrosis Pathological Conditions, Signs and Symptoms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0238790 BXGD004956 bone destruction
C0268162 BXGD005843 Pentosuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0280280 BXGD006731 stage, prostate cancer Neoplasms; Male Urogenital Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001380 Succinic acid 118.09
BXGC0002591 Potassium 39.1
BXGC0004199 2-Methylbutanoic acid 102.13
BXGC0005796 Butanoic acid 88.11
BXGC0047529 2-hydroxybutyric acid 104.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein