Showing entry for Ubiquitin carboxyl-terminal hydrolase 37


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017605
Protein NameUbiquitin carboxyl-terminal hydrolase 37
Uniport IdQ86T82
GeneUSP37
Gene Id57695
DomainUCH; UCH_N; UIM
Pfam PF00443   PF16674   PF02809  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0000082 G1/S transition of mitotic cell cycle
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0035871 protein K11-linked deubiquitination
Biological Process GO:0071108 protein K48-linked deubiquitination
Biological Process GO:0006275 regulation of DNA replication
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004843 thiol-dependent ubiquitin-specific protease activity
molecular function GO:0036459 thiol-dependent ubiquitinyl hydrolase activity
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-5688426 Deubiquitination
R-HSA-5689880 Ub-specific processing proteases
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0524957 BXGD009252 Corneal Topography
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein