Showing entry for Adult Medulloblastoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006607
Disease NameAdult Medulloblastoma
Disease CUI IdC0278876
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase 29904 reviewed Kinase
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O14641 BXGT004078 Segment polarity protein dishevelled homolog DVL-2 1856 reviewed Signaling
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14744 BXGT004089 Protein arginine N-methyltransferase 5 10419 reviewed Epigenetic regulator
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15169 BXGT004134 Axin-1 8312 reviewed
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43280 BXGT004582 Trehalase 11181 reviewed
O60341 BXGT004873 Lysine-specific histone demethylase 1A 23028 reviewed Epigenetic regulator
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O76064 BXGT005173 E3 ubiquitin-protein ligase RNF8 9025 reviewed
O94813 BXGT005337 Slit homolog 2 protein 9353 reviewed
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95271 BXGT005369 Poly [ADP-ribose] polymerase tankyrase-1 8658 reviewed
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 9448 reviewed Kinase
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00966 BXGT005707 Argininosuccinate synthase 445 reviewed Enzyme
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P05937 BXGT006396 Calbindin 793 reviewed Calcium-binding protein
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06493 BXGT006445 Cyclin-dependent kinase 1 983 reviewed Kinase
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06746 BXGT006496 DNA polymerase beta 5423 reviewed Enzyme
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11086 BXGT007652 Phenylethanolamine N-methyltransferase 5409 reviewed Enzyme
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15498 BXGT008133 Proto-oncogene vav 7409 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P17342 BXGT008302 Atrial natriuretic peptide receptor 3 4883 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P22033 BXGT008721 Methylmalonyl-CoA mutase, mitochondrial 4594 reviewed Enzyme
P22083 BXGT008727 Alpha-(1,3)-fucosyltransferase 4 2526 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23921 BXGT008927 Ribonucleoside-diphosphate reductase large subunit 6240 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24864 BXGT009000 G1/S-specific cyclin-E1 898 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29373 BXGT009337 Cellular retinoic acid-binding protein 2 1382 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P30304 BXGT009418 M-phase inducer phosphatase 1 993 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31644 BXGT009557 Gamma-aminobutyric acid receptor subunit alpha-5 2558 reviewed Ion channel
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P33981 BXGT009744 Dual specificity protein kinase TTK 7272 reviewed Kinase
P33991 BXGT009745 DNA replication licensing factor MCM4 4173 reviewed Enzyme
P34947 BXGT009774 G protein-coupled receptor kinase 5 2869 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 5605 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42261 BXGT010293 Glutamate receptor 1 2890 reviewed Ion channel
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43250 BXGT010372 G protein-coupled receptor kinase 6 2870 reviewed Kinase
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48729 BXGT010655 Casein kinase I isoform alpha 1452 reviewed Kinase
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P50120 BXGT010773 Retinol-binding protein 2 5948 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P53985 BXGT011022 Monocarboxylate transporter 1 6566 reviewed Transporter
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P54687 BXGT011067 Branched-chain-amino-acid aminotransferase, cytosolic 586 reviewed Enzyme
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P55201 BXGT011109 Peregrin 7862 reviewed
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62888 BXGT011469 60S ribosomal protein L30 6156 reviewed Nucleic acid binding
P62993 BXGT011480 Growth factor receptor-bound protein 2 2885 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P68431 BXGT011601 Histone H3.1 8968 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78325 BXGT011832 Disintegrin and metalloproteinase domain-containing protein 8 101 reviewed Enzyme
P78504 BXGT011844 Protein jagged-1 182 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 1020 reviewed Kinase
Q00536 BXGT012535 Cyclin-dependent kinase 16 5127 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q01974 BXGT012628 Tyrosine-protein kinase transmembrane receptor ROR2 4920 reviewed Kinase
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02880 BXGT012677 DNA topoisomerase 2-beta 7155 reviewed
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13163 BXGT013321 Dual specificity mitogen-activated protein kinase kinase 5 5607 reviewed Kinase
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13569 BXGT013378 G/T mismatch-specific thymine DNA glycosylase 6996 reviewed
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 8536 reviewed Kinase
Q14240 BXGT013458 Eukaryotic initiation factor 4A-II 1974 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase 9833 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14833 BXGT013508 Metabotropic glutamate receptor 4 2914 reviewed G-protein coupled receptor
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15059 BXGT013530 Bromodomain-containing protein 3 8019 reviewed Epigenetic regulator
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15375 BXGT013562 Ephrin type-A receptor 7 2045 reviewed Kinase
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15561 BXGT013578 Transcriptional enhancer factor TEF-3 7004 reviewed Transcription factor
Q15717 BXGT013589 ELAV-like protein 1 1994 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q2M385 BXGT014131 Macrophage-expressed gene 1 protein 219972 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q5T6L4 BXGT015848 Argininosuccinate synthase 1 isoform 1 445 unreviewed
Q5T7N2 BXGT015849 LINE-1 type transposase domain-containing protein 1 54596 reviewed
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q7RTN6 BXGT017085 STE20-related kinase adapter protein alpha 92335 reviewed Kinase
Q86T82 BXGT017605 Ubiquitin carboxyl-terminal hydrolase 37 57695 reviewed Enzyme
Q86XP3 BXGT017630 ATP-dependent RNA helicase DDX42 11325 reviewed
Q8IUF8 BXGT018334 Ribosomal oxygenase 2 84864 reviewed
Q8IV61 BXGT018340 Ras guanyl-releasing protein 3 25780 reviewed Enzyme modulator
Q8WZA1 BXGT019024 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 55624 reviewed
Q92616 BXGT019358 eIF-2-alpha kinase activator GCN1 10985 reviewed Enzyme modulator
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92794 BXGT019375 Histone acetyltransferase KAT6A 7994 reviewed Enzyme
Q92831 BXGT019380 Histone acetyltransferase KAT2B 8850 reviewed
Q92918 BXGT019394 Mitogen-activated protein kinase kinase kinase kinase 1 11184 reviewed Kinase
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q96T88 BXGT019747 E3 ubiquitin-protein ligase UHRF1 29128 reviewed
Q99759 BXGT019960 Mitogen-activated protein kinase kinase kinase 3 4215 reviewed Kinase
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q9BSQ5 BXGT020123 Cerebral cavernous malformations 2 protein 83605 reviewed
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9H3R0 BXGT020465 Lysine-specific demethylase 4C 23081 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H4W6 BXGT020478 Transcription factor COE3 253738 reviewed
Q9H6W3 BXGT020485 Ribosomal oxygenase 1 79697 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 2872 reviewed Kinase
Q9NRR6 BXGT021193 Phosphatidylinositol polyphosphate 5-phosphatase type IV 56623 reviewed
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 51776 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UH99 BXGT021693 SUN domain-containing protein 2 25777 reviewed Cellular structure
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UMX1 BXGT021778 Suppressor of fused homolog 51684 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPZ9 BXGT021804 Serine/threonine-protein kinase ICK 22858 reviewed Kinase
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9UQL6 BXGT021813 Histone deacetylase 5 10014 reviewed Epigenetic regulator
Q9Y219 BXGT022206 Protein jagged-2 3714 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y2U5 BXGT022248 Mitogen-activated protein kinase kinase kinase 2 10746 reviewed Kinase
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q9Y6X2 BXGT022343 E3 SUMO-protein ligase PIAS3 10401 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q13029 BXGT022688 PR domain zinc finger protein 2 7799 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q9P2E7 BXGT025815 Protocadherin-10 57575 reviewed
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease