Showing entry for Beta-2 adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018404
Protein NameBeta-2 adrenergic receptor
Uniport IdQ8K4Z4
GeneAdrb2
Gene Id100722663
Domain7tm_1
Pfam PF00001  
OrganismCavia porcellus (Guinea pig)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0045453 bone resorption
Biological Process GO:0050873 brown fat cell differentiation
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0002032 desensitization of G protein-coupled receptor signaling pathway by arrestin
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0031649 heat generation
Biological Process GO:0040015 negative regulation of multicellular organism growth
Biological Process GO:0045986 negative regulation of smooth muscle contraction
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:2000969 positive regulation of AMPA receptor activity
Biological Process GO:1901098 positive regulation of autophagosome maturation
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:1904504 positive regulation of lipophagy
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0061885 positive regulation of mini excitatory postsynaptic potential
Biological Process GO:0010739 positive regulation of protein kinase A signaling
Biological Process GO:0071902 positive regulation of protein serine/threonine kinase activity
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:0009409 response to cold
molecular function GO:0008179 adenylate cyclase binding
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0004941 beta2-adrenergic receptor activity
molecular function GO:0051380 norepinephrine binding
molecular function GO:0015459 potassium channel regulator activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0005769 early endosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005634 nucleus
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0021893 Norepinephrine 169.07
BXGC0031384 Epinephrine 183.09
BXGC0041240 Atenolol 266.16
BXGC0042222 Propranolol 259.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein