Showing entry for Diphosphoinositol polyphosphate phosphohydrolase 3-alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018562
Protein NameDiphosphoinositol polyphosphate phosphohydrolase 3-alpha
Uniport IdQ8NFP7
GeneNUDT10
Gene Id170685
DomainNUDIX
Pfam PF00293  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
Biological Process GO:1901909 diadenosine hexaphosphate catabolic process
Biological Process GO:1901907 diadenosine pentaphosphate catabolic process
Biological Process GO:0071543 diphosphoinositol polyphosphate metabolic process
Biological Process GO:0043647 inositol phosphate metabolic process
molecular function GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity
molecular function GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity
molecular function GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity
molecular function GO:0000298 endopolyphosphatase activity
molecular function GO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity
molecular function GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity
molecular function GO:0050072 m7G(5')pppN diphosphatase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483249 Inositol phosphate metabolism
R-HSA-1855167 Synthesis of pyrophosphates in the cytosol
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001403 BXGD000048 Addison Disease Immune System Diseases; Endocrine System Diseases
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0085292 BXGD003153 Stiff-Person Syndrome Immune System Diseases; Nervous System Diseases
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0085859 BXGD003254 Polyglandular Type I Autoimmune Syndrome Immune System Diseases; Endocrine System Diseases
C0178468 BXGD004029 Autoimmune thyroid disease Immune System Diseases; Endocrine System Diseases
C0271737 BXGD006252 Addison's disease due to autoimmunity Immune System Diseases; Endocrine System Diseases
C0342288 BXGD007456 Insulin-dependent diabetes mellitus secretory diarrhea syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0795864 BXGD010754 Smith-Magenis syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C2103602 BXGD016918 Autoimmune Primary Adrenal Insufficiency Immune System Diseases; Endocrine System Diseases
C3494489 BXGD018967 Autoimmune polyendocrinopathy syndrome, type 1 Immune System Diseases; Endocrine System Diseases
C3840565 BXGD019797 Autoimmune thyroid disease (AITD)
C3887896 BXGD019925 Primary Adrenal Insufficiency
C4316913 BXGD022714 Autoimmune Polyglandular Syndrome Pathological Conditions, Signs and Symptoms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein