adisease

Showing entry for Icterus

General Disease Information
BXGD Id	BXGD001537
Disease Name	Icterus
Disease CUI Id	C0022346
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025031 HP:0001574
Human Phenotype Ontology Term	Abnormality of the digestive system; Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O15554	BXGT004182	Intermediate conductance calcium-activated potassium channel protein 4	3783	reviewed	Ion channel
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60656	BXGT004889	UDP-glucuronosyltransferase 1-9	54600	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60701	BXGT004894	UDP-glucose 6-dehydrogenase	7358	reviewed
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75751	BXGT005150	Solute carrier family 22 member 3	6581	reviewed	Transporter
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95342	BXGT005373	Bile salt export pump	8647	reviewed	Transporter
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02549	BXGT005890	Spectrin alpha chain, erythrocytic 1	6708	reviewed
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04075	BXGT006145	Fructose-bisphosphate aldolase A	226	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05787	BXGT006385	Keratin, type II cytoskeletal 8	3856	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P07478	BXGT006630	Trypsin-2	5645	reviewed	Enzyme
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10301	BXGT007556	Ras-related protein R-Ras	6237	reviewed	Enzyme modulator
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10827	BXGT007623	Thyroid hormone receptor alpha	7067	reviewed	Nuclear receptor
P10828	BXGT007624	Thyroid hormone receptor beta	7068	reviewed	Nuclear receptor
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15085	BXGT008077	Carboxypeptidase A1	1357	reviewed	Enzyme
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16157	BXGT008203	Ankyrin-1	286	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P17174	BXGT008289	Aspartate aminotransferase, cytoplasmic	2805	reviewed
P19224	BXGT008468	UDP-glucuronosyltransferase 1-6	54578	reviewed
P19367	BXGT008476	Hexokinase-1	3098	reviewed	Kinase
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	5244	reviewed	Transporter
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	54657	reviewed
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24666	BXGT008986	Low molecular weight phosphotyrosine protein phosphatase	52	reviewed
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P30613	BXGT009447	Pyruvate kinase PKLR	5313	reviewed	Kinase
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35503	BXGT009840	UDP-glucuronosyltransferase 1-3	54659	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P38117	BXGT010027	Electron transfer flavoprotein subunit beta	2109	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P49748	BXGT010733	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	37	reviewed	Enzyme
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P51159	BXGT010839	Ras-related protein Rab-27A	5873	reviewed
P51857	BXGT010899	Aldo-keto reductase family 1 member D1	6718	reviewed	Enzyme
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P81172	BXGT011935	Hepcidin	57817	reviewed
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q14002	BXGT013433	Carcinoembryonic antigen-related cell adhesion molecule 7	1087	reviewed
Q14376	BXGT013464	UDP-glucose 4-epimerase	2582	reviewed
Q14973	BXGT013515	Sodium/bile acid cotransporter	6554	reviewed	Transporter
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q86SX6	BXGT017601	Glutaredoxin-related protein 5, mitochondrial	51218	reviewed	Enzyme
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IXH7	BXGT018359	Negative elongation factor C/D	51497	reviewed
Q8NFP7	BXGT018562	Diphosphoinositol polyphosphate phosphohydrolase 3-alpha	170685	reviewed	Enzyme
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99895	BXGT019974	Chymotrypsin-C	11330	reviewed
Q9HAW7	BXGT020508	UDP-glucuronosyltransferase 1-7	54577	reviewed
Q9HAW8	BXGT020509	UDP-glucuronosyltransferase 1-10	54575	reviewed
Q9HAW9	BXGT020510	UDP-glucuronosyltransferase 1-8	54576	reviewed
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	28234	reviewed	Transporter
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9UJS0	BXGT021727	Calcium-binding mitochondrial carrier protein Aralar2	10165	reviewed	Transporter
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
Q16134	BXGT022664	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	2110	reviewed	Enzyme
P26045	BXGT022810	Tyrosine-protein phosphatase non-receptor type 3	5774	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
P40198	BXGT023750	Carcinoembryonic antigen-related cell adhesion molecule 3	1084	reviewed
Q8NB49	BXGT024770	Phospholipid-transporting ATPase IG	286410	reviewed	Transporter
P07315	BXGT026109	Gamma-crystallin C	1420	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}