Showing entry for Voltage-gated hydrogen channel 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019638
Protein NameVoltage-gated hydrogen channel 1
Uniport IdQ96D96
GeneHVCN1
Gene Id84329
DomainIon_trans; VGPC1_C
Pfam PF00520   PF16799  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0071467 cellular response to pH
Biological Process GO:0071294 cellular response to zinc ion
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0032930 positive regulation of superoxide anion generation
Biological Process GO:1902600 proton transmembrane transport
Biological Process GO:0051453 regulation of intracellular pH
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0009268 response to pH
Biological Process GO:0010043 response to zinc ion
Biological Process GO:0035036 sperm-egg recognition
molecular function GO:0042802 identical protein binding
molecular function GO:0022843 voltage-gated cation channel activity
molecular function GO:0030171 voltage-gated proton channel activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0030670 phagocytic vesicle membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0030667 secretory granule membrane
cellular component GO:0035579 specific granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-1187000 Fertilization
R-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-1300642 Sperm Motility And Taxes
R-HSA-1474165 Reproduction
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024301 BXGD001759 Lymphoma, Follicular Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0042769 BXGD002999 Virus Diseases Infections
C0200638 BXGD004043 Eosinophil count procedure
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C3280031 BXGD018796 JOUBERT SYNDROME 13
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein