adisease

Showing entry for Channelopathies

General Disease Information
BXGD Id	BXGD013698
Disease Name	Channelopathies
Disease CUI Id	C1720983
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O15247	BXGT004142	Chloride intracellular channel protein 2	1193	reviewed	Ion channel
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60840	BXGT004901	Voltage-dependent L-type calcium channel subunit alpha-1F	778	reviewed	Ion channel
O95069	BXGT005348	Potassium channel subfamily K member 2	3776	reviewed	Ion channel
P00367	BXGT005517	Glutamate dehydrogenase 1, mitochondrial	2746	reviewed	Enzyme
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P15382	BXGT008116	Potassium voltage-gated channel subfamily E member 1	3753	reviewed	Ion channel
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P22304	BXGT008752	Iduronate 2-sulfatase	3423	reviewed
P22459	BXGT008773	Potassium voltage-gated channel subfamily A member 4	3739	reviewed	Ion channel
P22460	BXGT008774	Potassium voltage-gated channel subfamily A member 5	3741	reviewed	Ion channel
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P48544	BXGT010641	G protein-activated inward rectifier potassium channel 4	3762	reviewed	Ion channel
P48549	BXGT010644	G protein-activated inward rectifier potassium channel 1	3760	reviewed	Ion channel
P50993	BXGT010826	Sodium/potassium-transporting ATPase subunit alpha-2	477	reviewed	Transporter
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P51795	BXGT010891	H(+)/Cl(-) exchange transporter 5	1184	reviewed	Ion channel
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P54289	BXGT011040	Voltage-dependent calcium channel subunit alpha-2/delta-1	781	reviewed	Ion channel
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P61086	BXGT011357	Ubiquitin-conjugating enzyme E2 K	3093	reviewed
P78508	BXGT011845	ATP-sensitive inward rectifier potassium channel 10	3766	reviewed	Ion channel
Q01484	BXGT012592	Ankyrin-2	287	reviewed
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16836	BXGT013679	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	3033	reviewed
Q30154	BXGT014296	HLA class II histocompatibility antigen, DR beta 5 chain	3127	reviewed	Immune response
Q8IVS2	BXGT018349	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	27349	reviewed
Q8TD43	BXGT018806	Transient receptor potential cation channel subfamily M member 4	54795	reviewed	Ion channel
Q92736	BXGT019367	Ryanodine receptor 2	6262	reviewed	Ion channel
Q96D96	BXGT019638	Voltage-gated hydrogen channel 1	84329	reviewed	Ion channel
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q99959	BXGT019977	Plakophilin-2	5318	reviewed	Cellular structure
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9ULC4	BXGT021757	Malignant T-cell-amplified sequence 1	28985	reviewed	Receptor
Q9Y5Y9	BXGT022309	Sodium channel protein type 10 subunit alpha	6336	reviewed	Ion channel
P35523	BXGT023831	Chloride channel protein 1	1180	reviewed	Ion channel
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
A8K7I4	BXGT025277	Calcium-activated chloride channel regulator 1	1179	reviewed	Ion channel
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}