Showing entry for Phosphatidylinositol 4-kinase type 2-alpha



                       
General Target Information
BXGT IdBXGT020127
Protein NamePhosphatidylinositol 4-kinase type 2-alpha
Uniport IdQ9BTU6
GenePI4K2A
Gene Id55361
DomainPI3_PI4_kinase
Pfam PF00454  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00562 Inositol phosphate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007032 endosome organization
Biological Process GO:0007030 Golgi organization
Biological Process GO:0006661 phosphatidylinositol biosynthetic process
Biological Process GO:0046854 phosphatidylinositol phosphorylation
molecular function GO:0004430 1-phosphatidylinositol 4-kinase activity
molecular function GO:0035651 AP-3 adaptor complex binding
molecular function GO:0005524 ATP binding
molecular function GO:0000287 magnesium ion binding
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005768 endosome
cellular component GO:0035838 growing cell tip
cellular component GO:0044231 host cell presynaptic membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031224 intrinsic component of membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483255 PI Metabolism
R-HSA-1483257 Phospholipid metabolism
R-HSA-1660499 Synthesis of PIPs at the plasma membrane
R-HSA-1660514 Synthesis of PIPs at the Golgi membrane
R-HSA-1660516 Synthesis of PIPs at the early endosome membrane
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0079504 BXGD003080 Hermanski-Pudlak Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002605 Adenosine 267.24
BXGC0003943 Purine 120.11
BXGC0010354 Cytokinin B 225.25
BXGC0022630 7-methyladenine 149.07
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein