Showing entry for Neuronal acetylcholine receptor subunit alpha-9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021686
Protein NameNeuronal acetylcholine receptor subunit alpha-9
Uniport IdQ9UGM1
GeneCHRNA9
Gene Id55584
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
Biological Process GO:0042472 inner ear morphogenesis
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0050877 nervous system process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0007165 signal transduction
molecular function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular function GO:0005262 calcium channel activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005892 acetylcholine-gated channel complex
cellular component GO:0098981 cholinergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099060 integral component of postsynaptic specialization membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-181431 Acetylcholine binding and downstream events
R-HSA-622327 Postsynaptic nicotinic acetylcholine receptors
R-HSA-629594 Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007621 BXGD000468 Neoplastic Cell Transformation Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000434 Ethanol 46.07
BXGC0002796 Nicotine 162.23
BXGC0038169 (-)-Lobeline 337.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein