Showing entry for Nicotine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0002796
Compound NameNicotine
Structure
FormulaC10H14N2
InchiKeySNICXCGAKADSCV-JTQLQIEISA-N
SMILESCN1CCC[C@H]1C1=CN=CC=C1
InchiInChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
IUPAC3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
Molecular Weight162.23
Pubchem Id89594
Chembl IdCHEMBL3
Targets of Information Source
DrugBank DB00184
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 approved agonist
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 approved agonist
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 approved agonist
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 approved agonist
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 approved agonist
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 approved agonist
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 reviewed Ion channel CHRNA6 approved agonist
Q9UGM1 BXGT021686 Neuronal acetylcholine receptor subunit alpha-9 reviewed Ion channel CHRNA9 approved agonist
Q9GZZ6 BXGT020429 Neuronal acetylcholine receptor subunit alpha-10 reviewed Ion channel CHRNA10 approved agonist
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 approved agonist
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 approved agonist
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 approved inhibitor
P28329 BXGT009251 Choline O-acetyltransferase reviewed Enzyme CHAT approved inhibitor
PDB NCT
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P00183 BXGT005482 Camphor 5-monooxygenase reviewed camC - - - - -
P58154 BXGT011224 Acetylcholine-binding protein reviewed - - - 45.2 -
Q16696 BXGT013658 Cytochrome P450 2A13 reviewed CYP2A13 - - - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 - - - 470000 -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed CHRNA4 Ion channel - - - -
Q8WSF8 BXGT018982 Soluble acetylcholine receptor unreviewed - - - - -
F8G0P2 BXGT003319 Amine oxidase unreviewed PPS_4081 - - - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed CHRNA3 Ion channel - - - -
Binding DB 82070
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 740
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 40.7 -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 310 -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 12 - - -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 110 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 47 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 440 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 10 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 40 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 517 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 2400
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - 370 - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - - - 23000
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - >10000 - -
reviewed BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 5500 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 2.3 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 1 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1.4 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1.3 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 1.2 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 2.1 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 2 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 43 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 12 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 15 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 46 - - -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 112 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 10 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 443 - - -
reviewed BXGT005929 Acetylcholine receptor subunit beta reviewed CHRNB1 - 4 - -
reviewed BXGT005929 Acetylcholine receptor subunit beta reviewed CHRNB1 - 1 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 2100
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 7100
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 - 360000 - -
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 51000
reviewed BXGT005929 Acetylcholine receptor subunit beta reviewed CHRNB1 - - - 60000
reviewed BXGT005931 Acetylcholine receptor subunit delta reviewed chrnd - - - 160000
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 21000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 4000
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 4000 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 54000
reviewed BXGT005929 Acetylcholine receptor subunit beta reviewed CHRNB1 >10000 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 4000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 590
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 0.84 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1.5 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1.1 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 610 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 1610 - - -
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 320 - - -
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 4300
reviewed BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 103 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 9.1 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 129 - - -
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 47 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 5000
reviewed BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed Chrna9 - 2.4 - -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 4400 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 530 - - -
reviewed BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 70 - - -
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 260 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 9.8 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 23 - - -
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 5.5 - - -
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 29 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 4.9 - - -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 - 579429 - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - - - 86000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 1000
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 13000
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 15000 - - -
reviewed BXGT013658 Cytochrome P450 2A13 reviewed CYP2A13 72000 - - -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 - - 470000 -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 130000 - - -
reviewed BXGT013658 Cytochrome P450 2A13 reviewed CYP2A13 - - 54000 -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 109648
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 108700
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 450 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 6.8 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 3 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 234 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 250 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 320 -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 316 -
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 - 3.8 - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 - 28000 - -
reviewed BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 - - - 10000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 4 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 0.94 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 4700
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 9400
reviewed BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 - - - 180000
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - 16 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 4 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 620 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 2.3 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 480 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 43000000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 2 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 460 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 7200 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - 1.06 -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 12 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 47 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 481 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 11.1 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 469 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 1400 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 38000
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 220 - - -
reviewed BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 480 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 770 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 340 - - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 245471 - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 - >10000 - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 83000
reviewed BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed Chrnb4 73 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 130 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 6300 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 1748 - - -
reviewed BXGT005929 Acetylcholine receptor subunit beta reviewed CHRNB1 6270 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 6290 - - -
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 - - - 132000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 113000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 630 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 750 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 12000 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 24000 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 1500
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 22 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 600 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 150 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 16000 - - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 244300 - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 176 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 6600
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 91000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - 1.65 - -
reviewed BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 - - - 17000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 2110 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 290
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - 430 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 1
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 3000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 3000 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 496 - - -
reviewed BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 244 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 1071.52
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - 427 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - 426.58 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 295.12
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 295
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 5.5 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 23000
reviewed BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed Chrna9 - - 5 -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 1.01 - - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 245470.89 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 1.6 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 >10000 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 9400
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 1.5 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 1584.89
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 63.1 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 1000 - - -
reviewed BXGT008610 Cytochrome P450 2A5 reviewed Cyp2a5 - 159956 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 9.46 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 300
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 331.13 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 1023.29 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 316.23 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 12.59 - - -
reviewed BXGT021408 Solute carrier family 22 member 2 reviewed Slc22a2 50500 - - -
reviewed BXGT016060 Solute carrier family 22 member 1 reviewed Slc22a1 64300 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 479 -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 83 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 230 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 3800 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 0.6 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - 7600 - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - 1.2 - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - - - 24000
CHEMBL CHEMBL3
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 1 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Rmax '=' 74 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 5 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 5 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 98 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 98 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 40 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 40 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 100 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 100 %
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Rmax '=' 85 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 85 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 0 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 110 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 110 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 47 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 47 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 430 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 430 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 430 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 430 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 430 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 430 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 430 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 430 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 430 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 430 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 430 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 443 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 443 nM
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 530 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 530 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG Ki '=' 6270 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Ki '=' 6270 nM
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 Ki '=' 6270 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 Ki '=' 6270 nM
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Activity - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 113000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Rmax '=' 100 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 72 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 72 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 133000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 16 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 47 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 47 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 10 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 10 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 4 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 4 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 3000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 23 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 23 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Emax '=' 103 %
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 245470 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 260 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 260 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 K app '=' 6 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 K app '=' 6 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 K app '=' 6 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 K app '=' 6 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 K app '=' 6 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 K app '=' 6 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 K app '=' 6 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 K app '=' 6 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 K app '=' 6 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 K app '=' 6 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 K app '=' 6 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Emax '=' 102 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 40 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 40 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 250 nM
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Ki '=' 103 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 103 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 43 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 43 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 43000000 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 43000000 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 43000000 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 43000000 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 43000000 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 43000000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 43000000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 43000000 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 43000000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 43000000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 43000000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 61 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Efficacy '=' 61 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 23000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 1071 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 141 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 141 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 2400 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 2400 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 2 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 2 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 100 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 234 nM
P21687 BXGT008680 Lycopene beta-cyclase reviewed - crtY IC50 '=' 4800 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 22387 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 9 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 9 nM
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 316 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 29 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 29 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 120 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 120 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 430 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 430 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 288 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 288 nM
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 IC50 '=' 21000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Max '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Max '=' 100 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 260 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 260 nM
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 480 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 4 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 4 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Activity '=' 24 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Activity '=' 24 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 520 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Kinact '=' 71 min-1
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Ki '=' 12 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 12 nM
Q8WSF8 BXGT018982 Soluble acetylcholine receptor unreviewed - Ki '=' 2511 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Activity - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 0 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 91000 nM
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 33491 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 440 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 440 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Emax '=' 43 %
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 83000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 92 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Efficacy '=' 92 %
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 Efficacy '=' 90 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 90 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Efficacy '=' 90 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 90 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 290 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 290 nM
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Ki '=' 70 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 70 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 481 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 481 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 4 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 4 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 244299 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 EC50 '=' 17000 nM
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Inhibition '=' -3 %
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 28183 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 16000 nM
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 EC50 '=' 127 nM
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 reviewed Ion channel CHRNA6 EC50 '=' 127 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 127 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 127 nM
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Efficacy '=' 53 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Mean enhancement of binding '=' 4 -
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Mean enhancement of binding '=' 4 -
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Mean enhancement of binding '=' 4 -
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Mean enhancement of binding '=' 4 -
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Mean enhancement of binding '=' 4 -
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Mean enhancement of binding '=' 4 -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Mean enhancement of binding '=' 4 -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Mean enhancement of binding '=' 4 -
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Mean enhancement of binding '=' 4 -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Mean enhancement of binding '=' 4 -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Mean enhancement of binding '=' 4 -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 1 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 1 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 1 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 1 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 6 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 6 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 79432 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 1000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 73 nM
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 9400 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 9400 nM
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 620 nM
A9XFY4 BXGT001818 Nicotinic acetylcholine receptor alpha 5 subunit unreviewed - nAChRalpha5 IC50 '=' 11900 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 220 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND Ki '=' 5500 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 Ki '=' 5500 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG Ki '=' 5500 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Ki '=' 5500 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Kd '=' 478 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 331 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 2110 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 4000 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 2100 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 2100 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 29 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 29 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 770 nM
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 1 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 1 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 1 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 1 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 4300 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 4300 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 4 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 IC50 '=' 4 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 IC50 '=' 4 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 IC50 '=' 4 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 IC50 '=' 4 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 IC50 '=' 4 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '=' 4 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 4 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 IC50 '=' 4 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 4 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '=' 4 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 129 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 129 nM
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 3 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 3 nM
Q8WXA8 BXGT019008 5-hydroxytryptamine receptor 3C reviewed Ion channel HTR3C Ki '=' 71000 nM
Q70Z44 BXGT016686 5-hydroxytryptamine receptor 3D reviewed Ion channel HTR3D Ki '=' 71000 nM
O95264 BXGT005367 5-hydroxytryptamine receptor 3B reviewed Ion channel HTR3B Ki '=' 71000 nM
A5X5Y0 BXGT001376 5-hydroxytryptamine receptor 3E reviewed Ion channel HTR3E Ki '=' 71000 nM
P46098 BXGT010507 5-hydroxytryptamine receptor 3A reviewed Ion channel HTR3A Ki '=' 71000 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 101 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Enhancement '>' 5 %
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Enhancement '>' 5 %
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Enhancement '>' 5 %
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Enhancement '>' 5 %
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Enhancement '>' 5 %
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Enhancement '>' 5 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Enhancement '>' 5 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Enhancement '>' 5 %
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Enhancement '>' 5 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Enhancement '>' 5 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Enhancement '>' 5 %
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 Ki - - -
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 Ki - - -
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 Ki - - -
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 Ki - - -
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 6 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 IC50 '=' 6 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 IC50 '=' 6 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 IC50 '=' 6 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 IC50 '=' 6 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 IC50 '=' 6 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '=' 6 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 6 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 IC50 '=' 6 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 6 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '=' 6 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 88 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 88 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 93 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 93 %
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 26679 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki '=' 130000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 13 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 13 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 13 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 13 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 13 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 13 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 13 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 13 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 13 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 13 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 13 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 39810 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 600 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 600 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 12 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 '=' 579428 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 450 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 9332 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 9332 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 9400 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 9400 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 Ki '>' 10000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 Ki '>' 10000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 Ki '>' 10000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 Ki '>' 10000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Ki '>' 10000 nM
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 422 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 70 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 70 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 1000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 1000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 1 nM
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 0 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 0 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 0 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 0 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 0 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 0 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 0 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 0 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 0 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 0 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 '=' 4100000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 25118 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Activity '=' 101 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activity '=' 101 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 8000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 8000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 7943 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 7943 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 6290 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 1 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 1 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 1 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 1 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 244300 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 8 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 8 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 8 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 8 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 8 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 8 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 8 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 8 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 8 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 8 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 8 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 Ki '>' 5000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 Ki '>' 5000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 Ki '>' 5000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 Ki '>' 5000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Ki '>' 5000 nM
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '>' 10000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '>' 10000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 4000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 4000 nM
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 251 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 251 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 176 nM
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 Efficacy '=' 56 %
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 reviewed Ion channel CHRNA6 Efficacy '=' 56 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 56 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 56 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 2 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 2 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 2 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 2 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 2 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 2 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 2 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 2 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 2 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 2 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 2 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 891 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Enhancement '=' 8 %
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Enhancement '=' 8 %
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Enhancement '=' 8 %
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Enhancement '=' 8 %
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Enhancement '=' 8 %
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Enhancement '=' 8 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Enhancement '=' 8 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Enhancement '=' 8 %
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Enhancement '=' 8 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Enhancement '=' 8 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Enhancement '=' 8 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Inhibition '=' 100 %
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Inhibition '=' 100 %
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Inhibition '=' 100 %
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Inhibition '=' 100 %
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Inhibition '=' 100 %
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Inhibition '=' 100 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Inhibition '=' 100 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Inhibition '=' 100 %
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Inhibition '=' 100 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Inhibition '=' 100 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Inhibition '=' 100 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1500 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 300 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 300 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 46 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 46 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 15 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 15 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 320 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 320 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 2 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 2 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 7 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 67 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 67 nM
P20852 BXGT008610 Cytochrome P450 2A5 reviewed - Cyp2a5 IC50 '=' 159955 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki '=' 4400 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG Ki '>' 10000 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Ki '>' 10000 nM
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 Ki '>' 10000 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 Ki '>' 10000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 4000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 4000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 21000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 21000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 11 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 11 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 460 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 0 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 10000 nM
O15244 BXGT004140 Solute carrier family 22 member 2 reviewed Transporter SLC22A2 Activity - - -
O76082 BXGT005175 Solute carrier family 22 member 5 reviewed Transporter SLC22A5 Activity '=' 44 %
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 145 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG EC50 '=' 60000 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd EC50 '=' 60000 nM
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 EC50 '=' 60000 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 EC50 '=' 60000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Emax '=' 37 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Emax '=' 37 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 220 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 220 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1748 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 1023 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 12 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 12 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 23 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 23 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 1 %
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 IC50 '=' 32000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 IC50 '=' 32000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 IC50 '=' 32000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 IC50 '=' 32000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 IC50 '=' 32000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 1 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '=' 3 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 3 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 51000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 51000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 22 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 22 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 19 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 19 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 158 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 158 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 480 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Intrinsic activity '=' 59 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Response '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Response '=' 100 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Emax '=' 100 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Emax '=' 100 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 14 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 14 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 670 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Emax '=' 100 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 33 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 33 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 31 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 31 nM
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 24000 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Intrinsic activity '=' 100 %
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Rmax '=' 114 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 114 %
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 108700 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 IC50 '=' 360000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 IC50 '=' 360000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 IC50 '=' 360000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 IC50 '=' 360000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 IC50 '=' 360000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 12 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 12 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 7100 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 7100 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 Activity - - -
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 94 nM
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 39810 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 124 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 124 %
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND Ki '=' 6270 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 Ki '=' 6270 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG Ki '=' 6270 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Ki '=' 6270 nM
Q7RTT9 BXGT017086 Equilibrative nucleoside transporter 4 reviewed Transporter SLC29A4 Activity '=' -6 nanoampere
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Imax - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 13 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 13 nM
Q2MKA5 BXGT014139 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 IC50 '=' 4 nM
Q91X60 BXGT019305 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 IC50 '=' 4 nM
Q8R4G9 BXGT018687 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '=' 4 nM
Q8R493 BXGT018685 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '=' 4 nM
Q8BMN3 BXGT017918 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 IC50 '=' 4 nM
Q9R0W9 BXGT021409 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 IC50 '=' 4 nM
O70174 BXGT005058 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 4 nM
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 4 nM
Q9ERK7 BXGT020309 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 4 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 10000 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 EC50 '=' 10000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 5000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 5000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 13000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 469 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Dopamine release '=' 126 %
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Dopamine release '=' 126 %
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Dopamine release '=' 126 %
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Dopamine release '=' 126 %
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Dopamine release '=' 126 %
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Dopamine release '=' 126 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Dopamine release '=' 126 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Dopamine release '=' 126 %
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Dopamine release '=' 126 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Dopamine release '=' 126 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Dopamine release '=' 126 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 750 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 112 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 112 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 35 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 35 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 85 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 108 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 108 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 3 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Rmax '=' 3 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 6 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 6 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 6 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 6 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Inhibition - - -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Inhibition - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 290 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 290 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '>' 1000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 IC50 '>' 1000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 6606 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 6606 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 6600 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 6600 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 7200 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 IC50 '=' 21000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1400 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Activity '=' 0 ml
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activity '=' 0 ml
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 290 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 290 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Emax '=' 100 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Emax '=' 100 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 220 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 220 nM
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 88 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Efficacy '=' 88 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 70 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 5 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 5 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 15848 nM
O76082 BXGT005175 Solute carrier family 22 member 5 reviewed Transporter SLC22A5 Activity '=' 82 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki - - -
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 EC50 '=' 21000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 21000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 21000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 21000 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 EC50 '=' 21000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Imax '=' 0 -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Imax '=' 0 -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Activity '=' 0 ml
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Activity '=' 0 ml
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Inhibition - - -
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Inhibition - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 0 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 0 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 0 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 0 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 0 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 0 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 0 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 0 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 0 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 0 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG IC50 '=' 4 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd IC50 '=' 4 nM
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 IC50 '=' 4 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 IC50 '=' 4 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG Relative potency '=' 0 -
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Relative potency '=' 0 -
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 Relative potency '=' 0 -
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 Relative potency '=' 0 -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 3 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 IC50 '=' 3 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 IC50 '=' 3 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 IC50 '=' 3 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 IC50 '=' 3 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 IC50 '=' 3 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '=' 3 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 3 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 IC50 '=' 3 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 3 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '=' 3 nM
P46098 BXGT010507 5-hydroxytryptamine receptor 3A reviewed Ion channel HTR3A Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 4700 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 4700 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 15 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 3000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 3000 nM
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 133000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 370 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 370 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 132000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 132000 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 10000 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 10000 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
Q63089 BXGT016060 Solute carrier family 22 member 1 reviewed - Slc22a1 Ki '=' 64300 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 1 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 1 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 1 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 1 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 12000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 1584 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 630 nM
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 45000 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 45000 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 45000 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 45000 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 45000 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 45000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 45000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 45000 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 45000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 45000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 45000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 0 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 0 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 0 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 0 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 0 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 0 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 0 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 0 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 0 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 0 nM
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Activity - - -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Activity - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 590 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 590 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 630 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 630 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 12 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Activity '=' 89 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Activity '=' 89 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 530 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 530 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 IC50 '=' 2 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Kd '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 3 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 3 nM
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Rmax '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 517 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 IC50 '=' 28000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 IC50 '=' 28000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 IC50 '=' 28000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 IC50 '=' 28000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 IC50 '=' 28000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 86000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 86000 nM
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 2 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 2 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 IC50 '=' 7 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 IC50 '=' 7 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 IC50 '=' 7 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 IC50 '=' 7 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 IC50 '=' 7 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 IC50 '=' 7 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '=' 7 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 7 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 IC50 '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 7 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '=' 7 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG IC50 '=' 1 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd IC50 '=' 1 nM
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 IC50 '=' 1 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 IC50 '=' 1 nM
P02714 BXGT005930 Acetylcholine receptor subunit gamma reviewed - CHRNG Relative potency '=' 0 -
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Relative potency '=' 0 -
P02712 BXGT005929 Acetylcholine receptor subunit beta reviewed - CHRNB1 Relative potency '=' 0 -
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 Relative potency '=' 0 -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 1500 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 2 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 2 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 73 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Rmax '=' 73 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 10000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 10000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 0 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 0 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 2 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 2 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 8 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 8 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 7 nM
Q04844 BXGT012789 Acetylcholine receptor subunit epsilon reviewed Ion channel CHRNE EC50 '=' 65000 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND EC50 '=' 65000 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 EC50 '=' 65000 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG EC50 '=' 65000 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 EC50 '=' 65000 nM
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND Ki '=' 1480 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 Ki '=' 1480 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG Ki '=' 1480 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Ki '=' 1480 nM
Q9H015 BXGT020432 Solute carrier family 22 member 4 reviewed Transporter SLC22A4 Activity '=' 71 %
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Activity - - -
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 Efficacy - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy - - -
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Efficacy - - -
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Imax '=' 0 -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Imax '=' 0 -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Relative potency '=' 0 -
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Relative potency '=' 0 -
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Relative potency '=' 0 -
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Relative potency '=' 0 -
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Relative potency '=' 0 -
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Relative potency '=' 0 -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Relative potency '=' 0 -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Relative potency '=' 0 -
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Relative potency '=' 0 -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Relative potency '=' 0 -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Relative potency '=' 0 -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 44668 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 27 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 27 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 27 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 27 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 27 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 27 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 27 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 27 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 27 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 27 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 27 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 EC50 '=' 180000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 35000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 35000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 43000000 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd EC50 '=' 160000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 20000 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 EC50 '=' 20000 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 EC50 '=' 20000 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 EC50 '=' 20000 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 EC50 '=' 20000 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 EC50 '=' 20000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 20000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 20000 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 EC50 '=' 20000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 20000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 20000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Rmax '=' 97 %
A9XFY4 BXGT001818 Nicotinic acetylcholine receptor alpha 5 subunit unreviewed - nAChRalpha5 Activity '=' 11 uM
Q2MKA5 BXGT014139 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 1 nM
Q91X60 BXGT019305 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 1 nM
Q8R4G9 BXGT018687 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 1 nM
Q8R493 BXGT018685 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 1 nM
Q8BMN3 BXGT017918 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 1 nM
Q9R0W9 BXGT021409 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 1 nM
O70174 BXGT005058 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 1 nM
Q9ERK7 BXGT020309 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Imax - - -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Imax - - -
Q16696 BXGT013658 Cytochrome P450 2A13 reviewed - CYP2A13 Ki '=' 72000 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Kd '=' 470000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 394 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 394 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 9 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 9 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 199 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 199 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 9 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 9 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND EC50 '>' 1000 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 EC50 '>' 1000 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG EC50 '>' 1000 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 EC50 '>' 1000 nM
Q8WSF8 BXGT018982 Soluble acetylcholine receptor unreviewed - Ki '=' 598 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 6300 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 7000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 7000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Emax '=' 100 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Emax '=' 100 %
Q7RTT9 BXGT017086 Equilibrative nucleoside transporter 4 reviewed Transporter SLC29A4 Activity '=' -75 nanoampere
O88446 BXGT005272 Solute carrier family 22 member 3 reviewed - Slc22a3 Activity '=' 52 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 0 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 0 nM
Q8WSF8 BXGT018982 Soluble acetylcholine receptor unreviewed - Ki '=' 30 nM
P02710 BXGT005928 Acetylcholine receptor subunit alpha reviewed - CHRNA1 IC50 '=' 23100 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 54000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 51 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 51 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 15000 nM
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 610 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 1 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Activity '=' 37 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Activity '=' 37 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 IC50 '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 1 nM
Q8R4G9 BXGT018687 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 167 nM
Q8R493 BXGT018685 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 167 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 IC50 '>' 10000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 IC50 '>' 10000 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND Ki - - -
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 Ki - - -
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG Ki - - -
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Relative potency '=' 3 -
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Relative potency '=' 3 -
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Relative potency '=' 3 -
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Relative potency '=' 3 -
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Relative potency '=' 3 -
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Relative potency '=' 3 -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Relative potency '=' 3 -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Relative potency '=' 3 -
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Relative potency '=' 3 -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Relative potency '=' 3 -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Relative potency '=' 3 -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 1610 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Activity '=' 100 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Activity '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 5 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 5 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 5 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 5 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 5 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 5 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 5 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 5 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 5 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 5 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 5 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 496 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 2 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 2 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 '>' 10000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 3800 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 5 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 230 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 38000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 11000 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 11000 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 11000 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 11000 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 11000 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 11000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 11000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 11000 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 11000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 11000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 11000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 1 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 1 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 4109 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 340 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Stimulation '=' 100 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Stimulation '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Imax '=' 0 -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 19830 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 19830 nM
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 Efficacy '=' 26 %
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 reviewed Ion channel CHRNA6 Efficacy '=' 26 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Efficacy '=' 26 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 26 %
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 63 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 83 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 7 nM
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 11 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 11 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ratio '=' 0 -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 5 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 5 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 83 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '=' 430 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 IC50 '=' 430 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND Activity - - -
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 Activity - - -
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG Activity - - -
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 Activity - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 IC50 '=' 7600 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 295 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 295 nM
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 Activity - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Activity - - -
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Activity - - -
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activity - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 109647 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Activity - - -
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activity - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 210 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 210 nM
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 7 nM
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P10145 BXGT007542 Interleukin-8 reviewed Signaling CXCL8 Potency - 47307 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 72 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 72 nM
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Activity - - -
O70594 BXGT005072 Solute carrier family 22 member 5 reviewed - Slc22a5 Inhibition - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Emax '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Emax '=' 100 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 400 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 400 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 295 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 295 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 316 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 316 nM
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
Q9R141 BXGT021411 Solute carrier family 22 member 4 reviewed - Slc22a4 Activity '=' 29 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 1500 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 1500 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 1513 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 1513 nM
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 IC50 - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 - - -
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 IC50 - - -
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Activity '=' 43 %
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 3162 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Activity '=' 53 uM
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 23000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 23000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Activity - - -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Activity - - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 150 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 150 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 15848 nM
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 reviewed Ion channel CHRNA5 EC50 '=' 30000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 30000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 30000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 30000 nM
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
Q9R0W2 BXGT021408 Solute carrier family 22 member 2 reviewed - Slc22a2 Activity - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 10 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 10 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Emax '=' 40 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Emax '=' 40 %
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Ki '=' 5 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Kd '=' 10 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Kd '=' 10 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Kd '=' 10 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Kd '=' 10 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Kd '=' 10 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Kd '=' 10 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Kd '=' 10 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Kd '=' 10 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Kd '=' 10 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Kd '=' 10 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Kd '=' 10 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 230 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 230 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 70 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 70 %
O70174 BXGT005058 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 720 nM
Q9ERK7 BXGT020309 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 720 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Kd '=' 320 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 130 nM
Q16696 BXGT013658 Cytochrome P450 2A13 reviewed - CYP2A13 Kd '=' 54000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 1 nM
P21687 BXGT008680 Lycopene beta-cyclase reviewed - crtY Activity '=' 64 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 11 %
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' -16 %
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 28183 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 2 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 2 nM
Q07001 BXGT012907 Acetylcholine receptor subunit delta reviewed Ion channel CHRND IC50 '>' 1000 nM
P11230 BXGT007677 Acetylcholine receptor subunit beta reviewed Ion channel CHRNB1 IC50 '>' 1000 nM
P07510 BXGT006631 Acetylcholine receptor subunit gamma reviewed Ion channel CHRNG IC50 '>' 1000 nM
P02708 BXGT005927 Acetylcholine receptor subunit alpha reviewed Ion channel CHRNA1 IC50 '>' 1000 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Kd '=' 316 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Activity '=' 40 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Activity '=' 40 %
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 23000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 23000 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 2667 nM
Q9R0W2 BXGT021408 Solute carrier family 22 member 2 reviewed - Slc22a2 Ki '=' 50500 nM
P09482 BXGT006895 Neuronal acetylcholine receptor subunit alpha-4 reviewed - CHRNA4 Ki '=' 1 nM
A9XFY4 BXGT001818 Nicotinic acetylcholine receptor alpha 5 subunit unreviewed - nAChRalpha5 Ki '=' 2480 nM
Q7YWJ9 BXGT017236 Carboxylic ester hydrolase unreviewed - Ache IC50 '=' 2600000 nM
O70174 BXGT005058 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 724 nM
Q9ERK7 BXGT020309 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 724 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
Q8R493 BXGT018685 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 3 nM
Q9ERK7 BXGT020309 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 3 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 67 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 67 nM
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 2393 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 6 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '>' 10000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 IC50 '>' 10000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '=' 45 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Intrinsic activity '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Intrinsic activity '=' 100 %
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 427 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 427 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 4 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 4 nM
P25162 BXGT009029 Acetylcholine receptor subunit beta-like 2 reviewed - nAChRbeta2 Ki '=' 2700 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Activity - - -
O70174 BXGT005058 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 IC50 '=' 7 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 92 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 92 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 398 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 398 nM
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 reviewed Ion channel CHRNB3 IC50 '=' 84 nM
Q15825 BXGT013603 Neuronal acetylcholine receptor subunit alpha-6 reviewed Ion channel CHRNA6 IC50 '=' 84 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 IC50 '=' 84 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 84 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 261 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 261 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 IC50 '=' 426 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 IC50 '=' 426 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '>' 1000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '>' 1000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 40 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 40 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 140 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 140 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 250 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 250 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 47307 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Imax - - -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Imax - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Imax '=' 92 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Imax '=' 92 %
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 244 nM
P25162 BXGT009029 Acetylcholine receptor subunit beta-like 2 reviewed - nAChRbeta2 IC50 '=' 4000 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Ki '=' 440 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 440 nM
Q15822 BXGT013602 Neuronal acetylcholine receptor subunit alpha-2 reviewed Ion channel CHRNA2 Ki '=' 110 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Ki '=' 110 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Efficacy '=' 125 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Efficacy '=' 125 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Inhibition - - -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Inhibition - - -
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 3 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 3 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Activity '>' 80 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Activity '>' 80 %
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Activity - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Activity - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 1000000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 24000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 24000 nM
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 135000 nM
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Ki '=' 0 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Ki '=' 0 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Inhibition - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00015 Wild celery Apium graveolens Herbs and Spices
BXGF00041 Papaya Carica papaya Fruits
BXGF00094 Common walnut Juglans regia Nuts
BXGF00097 Sweet bay Laurus nobilis Herbs and Spices
BXGF00139 Pepper (Spice) Piper nigrum Herbs and Spices
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF03282 Ephedra intermedia Ephedra intermedia Medicinal Plant
BXGF04651 Garcinia lucida Garcinia lucida Medicinal Plant
BXGF04812 Meconopsis punicea Meconopsis punicea Medicinal Plant
BXGF04817 Euonymus alatus Euonymus alatus Medicinal Plant
BXGF04873 Papaver bracteatum Papaver bracteatum Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease