Showing entry for Leucine carboxyl methyltransferase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021716
Protein NameLeucine carboxyl methyltransferase 1
Uniport IdQ9UIC8
GeneLCMT1
Gene Id51451
DomainLCM
Pfam PF04072  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006464 cellular protein modification process
Biological Process GO:0006481 C-terminal protein methylation
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0031333 negative regulation of protein-containing complex assembly
Biological Process GO:0006479 protein methylation
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0010906 regulation of glucose metabolic process
Biological Process GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint
molecular function GO:0003880 protein C-terminal carboxyl O-methyltransferase activity
molecular function GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity
molecular function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0012684 BXGD000781 Blastocyst Disintegration Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0013937 BXGD000871 Embryo Resorption Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0017636 BXGD001131 Glioblastoma Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0752350 BXGD010722 Embryo Death Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0752351 BXGD010723 Embryo Loss Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1136082 BXGD011707 Embryo Disintegration Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0032575 Leucine 131.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein