Showing entry for SR-related and CTD-associated factor 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021798
Protein NameSR-related and CTD-associated factor 8
Uniport IdQ9UPN6
GeneSCAF8
Gene Id22828
DomainCTD_bind; RRM_1
Pfam PF04818   PF00076  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006378 mRNA polyadenylation
Biological Process GO:2000805 negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled
Biological Process GO:0032786 positive regulation of DNA-templated transcription, elongation
Biological Process GO:0006369 termination of RNA polymerase II transcription
molecular function GO:0003729 mRNA binding
molecular function GO:0003723 RNA binding
molecular function GO:0043175 RNA polymerase core enzyme binding
molecular function GO:0000993 RNA polymerase II complex binding
molecular function GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005849 mRNA cleavage factor complex
cellular component GO:0016363 nuclear matrix
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346629 BXGD007831 Malignant neoplasm of large intestine Digestive System Diseases; Neoplasms
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1837315 BXGD014218 COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
C2675481 BXGD017292 COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
C2677123 BXGD017364 COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
C3554460 BXGD019215 COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein