Showing entry for Malignant neoplasm of large intestine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007831
Disease NameMalignant neoplasm of large intestine
Disease CUI IdC0346629
MeSH Codes C06   C04  
Disease Class NameDigestive System Diseases; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14646 BXGT004079 Chromodomain-helicase-DNA-binding protein 1 1105 reviewed
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15230 BXGT004138 Laminin subunit alpha-5 3911 reviewed Enzyme modulator
O60494 BXGT004879 Cubilin 8029 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O95405 BXGT005379 Zinc finger FYVE domain-containing protein 9 9372 reviewed
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P18846 BXGT008430 Cyclic AMP-dependent transcription factor ATF-1 466 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22223 BXGT008744 Cadherin-3 1001 reviewed
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P39748 BXGT010134 Flap endonuclease 1 2237 reviewed Enzyme
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P54756 BXGT011074 Ephrin type-A receptor 5 2044 reviewed Kinase
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78317 BXGT011831 E3 ubiquitin-protein ligase RNF4 6047 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13796 BXGT013395 Protein Shroom2 357 reviewed
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q5T7N2 BXGT015849 LINE-1 type transposase domain-containing protein 1 54596 reviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q86VW1 BXGT017621 Solute carrier family 22 member 16 85413 reviewed Transporter
Q92959 BXGT019400 Solute carrier organic anion transporter family member 2A1 6578 reviewed Transporter
Q96JA1 BXGT019681 Leucine-rich repeats and immunoglobulin-like domains protein 1 26018 reviewed Receptor
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BQE3 BXGT020109 Tubulin alpha-1C chain 84790 reviewed Cellular structure
Q9NRA8 BXGT021184 Eukaryotic translation initiation factor 4E transporter 56478 reviewed
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9ULJ6 BXGT021761 Zinc finger MIZ domain-containing protein 1 57178 reviewed
Q9UPN3 BXGT021797 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 23499 reviewed Cellular structure
Q9UPN6 BXGT021798 SR-related and CTD-associated factor 8 22828 reviewed Nucleic acid binding
Q9NYP7 BXGT022661 Elongation of very long chain fatty acids protein 5 60481 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
O15198 BXGT024049 Mothers against decapentaplegic homolog 9 4093 reviewed Transcription factor
Q9H694 BXGT024116 Protein bicaudal C homolog 1 80114 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease