Showing entry for Endometrial Neoplasms


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000902
Disease NameEndometrial Neoplasms
Disease CUI IdC0014170
MeSH Codes C04   C13  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00204 BXGT003893 Sulfotransferase family cytosolic 2B member 1 6820 reviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15554 BXGT004182 Intermediate conductance calcium-activated potassium channel protein 4 3783 reviewed Ion channel
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08476 BXGT006774 Inhibin beta A chain 3624 reviewed Signaling
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P10909 BXGT007630 Clusterin 1191 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14061 BXGT007979 Estradiol 17-beta-dehydrogenase 1 3292 reviewed Enzyme
P14625 BXGT008029 Endoplasmin 7184 reviewed Chaperone
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P14923 BXGT008069 Junction plakoglobin 3728 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P30281 BXGT009416 G1/S-specific cyclin-D3 896 reviewed Enzyme modulator
P30305 BXGT009419 M-phase inducer phosphatase 2 994 reviewed Enzyme
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37059 BXGT009957 Estradiol 17-beta-dehydrogenase 2 3294 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P41161 BXGT010229 ETS translocation variant 5 2119 reviewed Transcription factor
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P46934 BXGT010553 E3 ubiquitin-protein ligase NEDD4 4734 reviewed Enzyme
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61604 BXGT011380 10 kDa heat shock protein, mitochondrial 3336 reviewed Chaperone
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P67870 BXGT011566 Casein kinase II subunit beta 1460 reviewed Kinase
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01469 BXGT012590 Fatty acid-binding protein 5 2171 reviewed
Q04828 BXGT012787 Aldo-keto reductase family 1 member C1 1645 reviewed Enzyme
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14542 BXGT013482 Equilibrative nucleoside transporter 2 3177 reviewed Transporter
Q14839 BXGT013509 Chromodomain-helicase-DNA-binding protein 4 1108 reviewed
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q86VW1 BXGT017621 Solute carrier family 22 member 16 85413 reviewed Transporter
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96EP1 BXGT019651 E3 ubiquitin-protein ligase CHFR 55743 reviewed Enzyme
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BZZ2 BXGT020205 Sialoadhesin 6614 reviewed
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UPN6 BXGT021798 SR-related and CTD-associated factor 8 22828 reviewed Nucleic acid binding
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
Q9Y6R4 BXGT022340 Mitogen-activated protein kinase kinase kinase 4 4216 reviewed Kinase
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
Q14258 BXGT024016 E3 ubiquitin/ISG15 ligase TRIM25 7706 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease