Showing entry for Cyclin-dependent kinase 11A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021808
Protein NameCyclin-dependent kinase 11A
Uniport IdQ9UQ88
GeneCDK11A
Gene Id728642
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0001558 regulation of cell growth
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0007346 regulation of mitotic cell cycle
Biological Process GO:0050684 regulation of mRNA processing
Biological Process GO:0006355 regulation of transcription, DNA-templated
molecular function GO:0005524 ATP binding
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380287 Centrosome maturation
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein