Showing entry for Nitric oxide synthase, brain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022398
Protein NameNitric oxide synthase, brain
Uniport IdQ9Z0J4
GeneNos1
Gene Id18125
DomainFAD_binding_1; Flavodoxin_1; NAD_binding_1; NO_synthase; PDZ
Pfam PF00667   PF00258   PF00175   PF02898   PF00595  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006527 arginine catabolic process
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0071872 cellular response to epinephrine stimulus
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0042738 exogenous drug catabolic process
Biological Process GO:0033555 multicellular organismal response to stress
Biological Process GO:0006936 muscle contraction
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0045776 negative regulation of blood pressure
Biological Process GO:0051926 negative regulation of calcium ion transport
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0051481 negative regulation of cytosolic calcium ion concentration
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:0061875 negative regulation of hepatic stellate cell contraction
Biological Process GO:0051346 negative regulation of hydrolase activity
Biological Process GO:0046676 negative regulation of insulin secretion
Biological Process GO:0034760 negative regulation of iron ion transmembrane transport
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0033137 negative regulation of peptidyl-serine phosphorylation
Biological Process GO:0043267 negative regulation of potassium ion transport
Biological Process GO:0051612 negative regulation of serotonin uptake
Biological Process GO:0045906 negative regulation of vasoconstriction
Biological Process GO:0006809 nitric oxide biosynthetic process
Biological Process GO:0007263 nitric oxide mediated signal transduction
Biological Process GO:0018119 peptidyl-cysteine S-nitrosylation
Biological Process GO:0140196 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0031284 positive regulation of guanylate cyclase activity
Biological Process GO:0035066 positive regulation of histone acetylation
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:1902307 positive regulation of sodium ion transmembrane transport
Biological Process GO:0098735 positive regulation of the force of heart contraction
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0008016 regulation of heart contraction
Biological Process GO:0050767 regulation of neurogenesis
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:0043627 response to estrogen
Biological Process GO:0009408 response to heat
Biological Process GO:0009725 response to hormone
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0098924 retrograde trans-synaptic signaling by nitric oxide
Biological Process GO:0006941 striated muscle contraction
Biological Process GO:0042311 vasodilation
molecular function GO:0051117 ATPase binding
molecular function GO:0046870 cadmium ion binding
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0019899 enzyme binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0010181 FMN binding
molecular function GO:0020037 heme binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0050661 NADP binding
molecular function GO:0070402 NADPH binding
molecular function GO:0003958 NADPH-hemoprotein reductase activity
molecular function GO:0004517 nitric-oxide synthase activity
molecular function GO:0016491 oxidoreductase activity
molecular function GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0017080 sodium channel regulator activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0042582 azurophil granule
cellular component GO:0071944 cell periphery
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0031965 nuclear membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0001917 photoreceptor inner segment
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0099092 postsynaptic density, intracellular component
cellular component GO:0099091 postsynaptic specialization, intracellular component
cellular component GO:0032991 protein-containing complex
cellular component GO:0042383 sarcolemma
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0033017 sarcoplasmic reticulum membrane
cellular component GO:0030141 secretory granule
cellular component GO:0045202 synapse
cellular component GO:0030315 T-tubule
cellular component GO:0012506 vesicle membrane
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000247 L-Targinine 188.23
BXGC0002916 Melatonin 232.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein