Showing entry for Beclin 1-associated autophagy-related key regulator


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024205
Protein NameBeclin 1-associated autophagy-related key regulator
Uniport IdQ6ZNE5
GeneATG14
Gene Id22863
DomainAtg14
Pfam PF10186  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000045 autophagosome assembly
Biological Process GO:0016240 autophagosome membrane docking
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0008333 endosome to lysosome transport
Biological Process GO:0016236 macroautophagy
Biological Process GO:0000423 mitophagy
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0010608 posttranscriptional regulation of gene expression
Biological Process GO:0061635 regulation of protein complex stability
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:0090207 regulation of triglyceride metabolic process
Biological Process GO:0098780 response to mitochondrial depolarisation
molecular function GO:0051020 GTPase binding
cellular component GO:0005776 autophagosome
cellular component GO:0000421 autophagosome membrane
cellular component GO:0005930 axoneme
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0097629 extrinsic component of omegasome membrane
cellular component GO:0097632 extrinsic component of phagophore assembly site membrane
cellular component GO:0044233 mitochondria-associated endoplasmic reticulum membrane
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0034045 phagophore assembly site membrane
cellular component GO:0035032 phosphatidylinositol 3-kinase complex, class III
Reactome
Pathway Id Pathway Name
R-HSA-1632852 Macroautophagy
R-HSA-9612973 Autophagy
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0042769 BXGD002999 Virus Diseases Infections
C0200638 BXGD004043 Eosinophil count procedure
C0202202 BXGD004082 Protein measurement
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0429468 BXGD008651 Anovulatory (finding) Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein