Showing entry for Intracranial Aneurysm


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000478
Disease NameIntracranial Aneurysm
Disease CUI IdC0007766
MeSH Codes C10   C14  
Disease Class NameNervous System Diseases; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707   HP:0001626  
Human Phenotype Ontology TermAbnormality of the nervous system; Abnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02724 BXGT005934 Glycophorin-A 2993 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P12429 BXGT007814 Annexin A3 306 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16152 BXGT008201 Carbonyl reductase [NADPH] 1 873 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20062 BXGT008543 Transcobalamin-2 6948 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P23468 BXGT008870 Receptor-type tyrosine-protein phosphatase delta 5789 reviewed Enzyme
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25774 BXGT009066 Cathepsin S 1520 reviewed Enzyme
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29536 BXGT009361 Leiomodin-1 25802 reviewed Cellular structure
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41252 BXGT010245 Isoleucine--tRNA ligase, cytoplasmic 3376 reviewed Enzyme
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43116 BXGT010357 Prostaglandin E2 receptor EP2 subtype 5732 reviewed G-protein coupled receptor
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50747 BXGT010817 Biotin--protein ligase 3141 reviewed Enzyme
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P68431 BXGT011601 Histone H3.1 8968 reviewed
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta 816 reviewed Kinase
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q8N4C8 BXGT018510 Misshapen-like kinase 1 50488 reviewed Kinase
Q8TAF3 BXGT018786 WD repeat-containing protein 48 57599 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8WXR4 BXGT019015 Myosin-IIIb 140469 reviewed Kinase
Q8WYK2 BXGT019020 Jun dimerization protein 2 122953 reviewed Transcription factor
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q96PN6 BXGT019709 Adenylate cyclase type 10 55811 reviewed
Q96SB4 BXGT019740 SRSF protein kinase 1 6732 reviewed Kinase
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9H0P0 BXGT020439 Cytosolic 5'-nucleotidase 3A 51251 reviewed Enzyme
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H8M5 BXGT020496 Metal transporter CNNM2 54805 reviewed
Q9UI33 BXGT021712 Sodium channel protein type 11 subunit alpha 11280 reviewed Ion channel
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y5K2 BXGT022293 Kallikrein-4 9622 reviewed Enzyme
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q13029 BXGT022688 PR domain zinc finger protein 2 7799 reviewed
P35240 BXGT022927 Merlin 4771 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
O15085 BXGT023125 Rho guanine nucleotide exchange factor 11 9826 reviewed
Q16254 BXGT023368 Transcription factor E2F4 1874 reviewed Nucleic acid binding
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P56703 BXGT023722 Proto-oncogene Wnt-3 7473 reviewed Signaling
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
Q6ZNE5 BXGT024205 Beclin 1-associated autophagy-related key regulator 22863 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q9P121 BXGT025711 Neurotrimin 50863 reviewed
Q8NI99 BXGT025986 Angiopoietin-related protein 6 83854 reviewed Signaling
P58215 BXGT026106 Lysyl oxidase homolog 3 84695 reviewed
Q96JB6 BXGT026118 Lysyl oxidase homolog 4 84171 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease