adisease

Showing entry for Ketosis

General Disease Information
BXGD Id	BXGD001567
Disease Name	Ketosis
Disease CUI Id	C0022638
MeSH Codes	C18
Disease Class Name	Nutritional and Metabolic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001939
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02763	BXGT005951	Alpha-1-acid glycoprotein 1	5004	reviewed
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P02818	BXGT005969	Osteocalcin	632	reviewed
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P08574	BXGT006792	Cytochrome c1, heme protein, mitochondrial	1537	reviewed
P09467	BXGT006893	Fructose-1,6-bisphosphatase 1	2203	reviewed	Enzyme
P11168	BXGT007663	Solute carrier family 2, facilitated glucose transporter member 2	6514	reviewed	Transporter
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12694	BXGT007835	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	593	reviewed
P14735	BXGT008042	Insulin-degrading enzyme	3416	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15735	BXGT008151	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	5261	reviewed	Kinase
P21953	BXGT008711	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	594	reviewed	Enzyme
P22680	BXGT008794	Cholesterol 7-alpha-monooxygenase	1581	reviewed	Enzyme
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P24666	BXGT008986	Low molecular weight phosphotyrosine protein phosphatase	52	reviewed
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P35218	BXGT009796	Carbonic anhydrase 5A, mitochondrial	763	reviewed
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P36956	BXGT009947	Sterol regulatory element-binding protein 1	6720	reviewed
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P46019	BXGT010498	Phosphorylase b kinase regulatory subunit alpha, liver isoform	5256	reviewed	Kinase
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55809	BXGT011127	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial	5019	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q0VD83	BXGT013179	Apolipoprotein B receptor	55911	reviewed
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14573	BXGT013486	Inositol 1,4,5-trisphosphate receptor type 3	3710	reviewed	Ion channel
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q2TU34	BXGT014223	Fructose-1,6-bisphosphatase 1	2203	unreviewed
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8IVS2	BXGT018349	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	27349	reviewed
Q8WXH5	BXGT019012	Suppressor of cytokine signaling 4	122809	reviewed	Enzyme modulator
Q96EY8	BXGT019655	Corrinoid adenosyltransferase	326625	reviewed	Enzyme
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HCC0	BXGT020530	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	64087	reviewed	Enzyme
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9P0L2	BXGT021289	Serine/threonine-protein kinase MARK1	4139	reviewed	Kinase
Q9ULC4	BXGT021757	Malignant T-cell-amplified sequence 1	28985	reviewed	Receptor
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
Q6ZNE5	BXGT024205	Beclin 1-associated autophagy-related key regulator	22863	reviewed
P21926	BXGT024578	CD9 antigen	928	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}