Showing entry for Phospholipid-transporting ATPase IG



                       
General Target Information
BXGT IdBXGT024770
Protein NamePhospholipid-transporting ATPase IG
Uniport IdQ8NB49
GeneATP11C
Gene Id286410
DomainCation_ATPase; E1-E2_ATPase; PhoLip_ATPase_C; PhoLip_ATPase_N
Pfam PF16212   PF16209  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0045579 positive regulation of B cell differentiation
Biological Process GO:0002329 pre-B cell differentiation
molecular function GO:0140326 ATPase-coupled intramembrane lipid transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0000287 magnesium ion binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-936837 Ion transport by P-type ATPases
R-HSA-983712 Ion channel transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002881 BXGD000140 Anemia, Hemolytic, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0008372 BXGD000535 Intrahepatic Cholestasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0268307 BXGD005892 Conjugated hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0860204 BXGD011219 Cholestatic liver disease Digestive System Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1321907 BXGD012451 Congenital absence of parathyroid gland Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C1845977 BXGD014769 X- linked recessive
C4551898 BXGD023434 Cholestasis, progressive familial intrahepatic 1 Digestive System Diseases
C4746970 BXGD023964 HEMOLYTIC ANEMIA, CONGENITAL, X-LINKED
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein