Showing entry for Cis-aconitate decarboxylase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025414
Protein NameCis-aconitate decarboxylase
Uniport IdA6NK06
GeneACOD1
Gene Id730249
DomainMmgE_PrpD
Pfam PF03972  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035458 cellular response to interferon-beta
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0071347 cellular response to interleukin-1
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071219 cellular response to molecule of bacterial origin
Biological Process GO:0071393 cellular response to progesterone stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0006952 defense response
Biological Process GO:0051607 defense response to virus
Biological Process GO:0007566 embryo implantation
Biological Process GO:0006954 inflammatory response
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0045824 negative regulation of innate immune response
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0034136 negative regulation of toll-like receptor 2 signaling pathway
Biological Process GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
Biological Process GO:0032480 negative regulation of type I interferon production
Biological Process GO:0002760 positive regulation of antimicrobial humoral response
Biological Process GO:2000379 positive regulation of reactive oxygen species metabolic process
Biological Process GO:0072573 tolerance induction to lipopolysaccharide
molecular function GO:0047613 aconitate decarboxylase activity
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017638 BXGD001132 Glioma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0042769 BXGD002999 Virus Diseases Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005066 2R,3R-Butanediol 90.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein