adisease

Showing entry for Lung diseases

General Disease Information
BXGD Id	BXGD001732
Disease Name	Lung diseases
Disease CUI Id	C0024115
MeSH Codes	C08
Disease Class Name	Respiratory Tract Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002086
Human Phenotype Ontology Term	Abnormality of the respiratory system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00602	BXGT003940	Ficolin-1	2219	reviewed	Signaling
O00625	BXGT003941	Pirin	8544	reviewed	Transcription factor
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15553	BXGT004181	Pyrin	4210	reviewed
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
O43570	BXGT004601	Carbonic anhydrase 12	771	reviewed
O43597	BXGT004602	Protein sprouty homolog 2	10253	reviewed	Signaling
O43813	BXGT004628	Glutathione S-transferase LANCL1	10314	reviewed
O43854	BXGT004630	EGF-like repeat and discoidin I-like domain-containing protein 3	10085	reviewed	Enzyme
O43915	BXGT004636	Vascular endothelial growth factor D	2277	reviewed	Signaling
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
O75369	BXGT005119	Filamin-B	2317	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O94759	BXGT005327	Transient receptor potential cation channel subfamily M member 2	7226	reviewed	Ion channel
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
O95257	BXGT005365	Growth arrest and DNA damage-inducible protein GADD45 gamma	10912	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02760	BXGT005948	Protein AMBP	259	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04004	BXGT006125	Vitronectin	7448	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04424	BXGT006214	Argininosuccinate lyase	435	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04732	BXGT006252	Metallothionein-1E	4493	reviewed
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P06126	BXGT006412	T-cell surface glycoprotein CD1a	909	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06239	BXGT006427	Tyrosine-protein kinase Lck	3932	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07814	BXGT006680	Bifunctional glutamate/proline--tRNA ligase	2058	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08311	BXGT006762	Cathepsin G	1511	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P08865	BXGT006832	40S ribosomal protein SA	3921	reviewed	Nucleic acid binding
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09668	BXGT006914	Pro-cathepsin H	1512	reviewed	Enzyme
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P11717	BXGT007740	Cation-independent mannose-6-phosphate receptor	3482	reviewed	Receptor
P11766	BXGT007745	Alcohol dehydrogenase class-3	128	reviewed	Enzyme
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15311	BXGT008106	Ezrin	7430	reviewed	Cellular structure
P15336	BXGT008109	Cyclic AMP-dependent transcription factor ATF-2	1386	reviewed	Transcription factor
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15813	BXGT008158	Antigen-presenting glycoprotein CD1d	912	reviewed
P15941	BXGT008176	Mucin-1	4582	reviewed
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16066	BXGT008185	Atrial natriuretic peptide receptor 1	4881	reviewed	Kinase
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17676	BXGT008327	CCAAT/enhancer-binding protein beta	1051	reviewed	Transcription factor
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P21333	BXGT008638	Filamin-A	2316	reviewed
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P21796	BXGT008690	Voltage-dependent anion-selective channel protein 1	7416	reviewed
P22352	BXGT008758	Glutathione peroxidase 3	2878	reviewed	Enzyme
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P24855	BXGT008998	Deoxyribonuclease-1	1773	reviewed
P25024	BXGT009005	C-X-C chemokine receptor type 1	3577	reviewed	G-protein coupled receptor
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25774	BXGT009066	Cathepsin S	1520	reviewed	Enzyme
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28562	BXGT009270	Dual specificity protein phosphatase 1	1843	reviewed
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29275	BXGT009328	Adenosine receptor A2b	136	reviewed	G-protein coupled receptor
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32929	BXGT009682	Cystathionine gamma-lyase	1491	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P33981	BXGT009744	Dual specificity protein kinase TTK	7272	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35247	BXGT009804	Pulmonary surfactant-associated protein D	6441	reviewed	Surfactant
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35408	BXGT009828	Prostaglandin E2 receptor EP4 subtype	5734	reviewed	G-protein coupled receptor
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35580	BXGT009853	Myosin-10	4628	reviewed
P35754	BXGT009863	Glutaredoxin-1	2745	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38484	BXGT010042	Interferon gamma receptor 2	3460	reviewed	Receptor
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40199	BXGT010166	Carcinoembryonic antigen-related cell adhesion molecule 6	4680	reviewed
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P48551	BXGT010645	Interferon alpha/beta receptor 2	3455	reviewed	Receptor
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49591	BXGT010715	Serine--tRNA ligase, cytoplasmic	6301	reviewed	Enzyme
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50579	BXGT010812	Methionine aminopeptidase 2	10988	reviewed
P50750	BXGT010818	Cyclin-dependent kinase 9	1025	reviewed	Kinase
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
P51665	BXGT010874	26S proteasome non-ATPase regulatory subunit 7	5713	reviewed	Enzyme
P51677	BXGT010876	C-C chemokine receptor type 3	1232	reviewed	G-protein coupled receptor
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P51884	BXGT010903	Lumican	4060	reviewed
P53396	BXGT010988	ATP-citrate synthase	47	reviewed	Enzyme
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P54707	BXGT011068	Potassium-transporting ATPase alpha chain 2	479	reviewed	Transporter
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55318	BXGT011119	Hepatocyte nuclear factor 3-gamma	3171	reviewed	Transcription factor
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P56192	BXGT011149	Methionine--tRNA ligase, cytoplasmic	4141	reviewed
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P78527	BXGT011846	DNA-dependent protein kinase catalytic subunit	5591	reviewed	Kinase
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P98066	BXGT012225	Tumor necrosis factor-inducible gene 6 protein	7130	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q01970	BXGT012627	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	5331	reviewed	Enzyme
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q03403	BXGT012712	Trefoil factor 2	7032	reviewed	Signaling
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q05397	BXGT012815	Focal adhesion kinase 1	5747	reviewed	Kinase
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q08050	BXGT012958	Forkhead box protein M1	2305	reviewed
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q10588	BXGT013202	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2	683	reviewed	Enzyme
Q13118	BXGT013312	Krueppel-like factor 10	7071	reviewed	Nucleic acid binding
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q14002	BXGT013433	Carcinoembryonic antigen-related cell adhesion molecule 7	1087	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15257	BXGT013554	Serine/threonine-protein phosphatase 2A activator	5524	reviewed	Enzyme modulator
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15811	BXGT013600	Intersectin-1	6453	reviewed	Enzyme modulator
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16881	BXGT013688	Thioredoxin reductase 1, cytoplasmic	7296	reviewed	Enzyme
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6GTX8	BXGT016315	Leukocyte-associated immunoglobulin-like receptor 1	3903	reviewed	Receptor
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q6ZMJ4	BXGT016628	Interleukin-34	146433	reviewed
Q7KZI7	BXGT016990	Serine/threonine-protein kinase MARK2	2011	reviewed	Kinase
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q86X55	BXGT017627	Histone-arginine methyltransferase CARM1	10498	reviewed	Epigenetic regulator
Q8IXI2	BXGT018361	Mitochondrial Rho GTPase 1	55288	reviewed	Enzyme modulator
Q8IYS5	BXGT018369	Osteoclast-associated immunoglobulin-like receptor	126014	reviewed
Q8N884	BXGT018528	Cyclic GMP-AMP synthase	115004	reviewed
Q8TCG1	BXGT018797	Protein CIP2A	57650	reviewed
Q8TDU6	BXGT018814	G-protein coupled bile acid receptor 1	151306	reviewed	G-protein coupled receptor
Q8WXI8	BXGT019014	C-type lectin domain family 4 member D	338339	reviewed
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99581	BXGT019937	Protein FEV	54738	reviewed	Transcription factor
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q99808	BXGT019964	Equilibrative nucleoside transporter 1	2030	reviewed	Transporter
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q99873	BXGT019972	Protein arginine N-methyltransferase 1	3276	reviewed	Epigenetic regulator
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9H015	BXGT020432	Solute carrier family 22 member 4	6583	reviewed	Transporter
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NP55	BXGT021141	BPI fold-containing family A member 1	51297	reviewed
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRA0	BXGT021183	Sphingosine kinase 2	56848	reviewed	Kinase
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBB5	BXGT021649	Methyl-CpG-binding domain protein 2	8932	reviewed	Epigenetic regulator
Q9UBE8	BXGT021652	Serine/threonine-protein kinase NLK	51701	reviewed	Kinase
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UJU2	BXGT021730	Lymphoid enhancer-binding factor 1	51176	reviewed
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9ULW8	BXGT021768	Protein-arginine deiminase type-3	51702	reviewed
Q9ULY5	BXGT021770	C-type lectin domain family 4 member E	26253	reviewed	Receptor
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9UN76	BXGT021781	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	11254	reviewed	Transporter
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2J8	BXGT022237	Protein-arginine deiminase type-2	11240	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y4K0	BXGT022280	Lysyl oxidase homolog 2	4017	reviewed
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y6Y9	BXGT022346	Lymphocyte antigen 96	23643	reviewed	Receptor
P35232	BXGT022663	Prohibitin	5245	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
A9YTQ3	BXGT023537	Aryl hydrocarbon receptor repressor	57491	reviewed	Transcription factor
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P56703	BXGT023722	Proto-oncogene Wnt-3	7473	reviewed	Signaling
P40198	BXGT023750	Carcinoembryonic antigen-related cell adhesion molecule 3	1084	reviewed
Q13007	BXGT023883	Interleukin-24	11009	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
Q15583	BXGT024027	Homeobox protein TGIF1	7050	reviewed	Enzyme
O15198	BXGT024049	Mothers against decapentaplegic homolog 9	4093	reviewed	Transcription factor
Q13432	BXGT024144	Protein unc-119 homolog A	9094	reviewed	Receptor
P21926	BXGT024578	CD9 antigen	928	reviewed
P20809	BXGT025043	Interleukin-11	3589	reviewed
P49366	BXGT025175	Deoxyhypusine synthase	1725	reviewed
P53621	BXGT025196	Coatomer subunit alpha	1314	reviewed	Transporter
A6NK06	BXGT025414	Cis-aconitate decarboxylase	730249	reviewed
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed
Q9P121	BXGT025711	Neurotrimin	50863	reviewed
P61916	BXGT025881	NPC intracellular cholesterol transporter 2	10577	reviewed
Q7LBE3	BXGT026071	Solute carrier family 26 member 9	115019	reviewed	Transporter
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}