Showing entry for Peripheral Arterial Diseases


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013564
Disease NamePeripheral Arterial Diseases
Disease CUI IdC1704436
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00487 BXGT003931 26S proteasome non-ATPase regulatory subunit 14 10213 reviewed Enzyme
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O43293 BXGT004584 Death-associated protein kinase 3 1613 reviewed Kinase
O60494 BXGT004879 Cubilin 8029 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60701 BXGT004894 UDP-glucose 6-dehydrogenase 7358 reviewed
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 8989 reviewed Ion channel
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00748 BXGT005640 Coagulation factor XII 2161 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02675 BXGT005916 Fibrinogen beta chain 2244 reviewed Signaling
P02679 BXGT005918 Fibrinogen gamma chain 2266 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P02750 BXGT005942 Leucine-rich alpha-2-glycoprotein 116844 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03951 BXGT006117 Coagulation factor XI 2160 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05546 BXGT006367 Heparin cofactor 2 3053 reviewed Enzyme modulator
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07438 BXGT006625 Metallothionein-1B 4490 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09958 BXGT006950 Furin 5045 reviewed Enzyme
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10114 BXGT007539 Ras-related protein Rap-2a 5911 reviewed Enzyme modulator
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17174 BXGT008289 Aspartate aminotransferase, cytoplasmic 2805 reviewed
P17342 BXGT008302 Atrial natriuretic peptide receptor 3 4883 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6715 reviewed Enzyme
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 1143 reviewed Ion channel
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 1136 reviewed Ion channel
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P46939 BXGT010555 Utrophin 7402 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15554 BXGT013577 Telomeric repeat-binding factor 2 7014 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q969Q1 BXGT019610 E3 ubiquitin-protein ligase TRIM63 84676 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q99523 BXGT019929 Sortilin 6272 reviewed Transporter
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BV57 BXGT020140 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 55256 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H6X2 BXGT020486 Anthrax toxin receptor 1 84168 reviewed Receptor
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NR19 BXGT021175 Acetyl-coenzyme A synthetase, cytoplasmic 55902 reviewed Enzyme
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase 23043 reviewed Kinase
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULC6 BXGT021759 Protein-arginine deiminase type-1 29943 reviewed
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UNA0 BXGT021784 A disintegrin and metalloproteinase with thrombospondin motifs 5 11096 reviewed Enzyme
Q9UPN3 BXGT021797 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 23499 reviewed Cellular structure
Q9Y2J8 BXGT022237 Protein-arginine deiminase type-2 11240 reviewed
Q9Y6M9 BXGT022336 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 4715 reviewed Enzyme
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
Q9H040 BXGT024831 SprT-like domain-containing protein Spartan 83932 reviewed
A6NK06 BXGT025414 Cis-aconitate decarboxylase 730249 reviewed
O00410 BXGT025968 Importin-5 3843 reviewed Enzyme modulator
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
Q8NI99 BXGT025986 Angiopoietin-related protein 6 83854 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease