Showing entry for Ubiquitin carboxyl-terminal hydrolase 47


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026122
Protein NameUbiquitin carboxyl-terminal hydrolase 47
Uniport IdQ96K76
GeneUSP47
Gene Id55031
DomainUCH
Pfam PF00443  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006284 base-excision repair
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0035520 monoubiquitinated protein deubiquitination
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
Biological Process GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0042493 response to drug
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0004843 thiol-dependent ubiquitin-specific protease activity
molecular function GO:0036459 thiol-dependent ubiquitinyl hydrolase activity
molecular function GO:0101005 ubiquitinyl hydrolase activity
molecular function GO:0071987 WD40-repeat domain binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0019005 SCF ubiquitin ligase complex
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-5688426 Deubiquitination
R-HSA-5689880 Ub-specific processing proteases
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0427460 BXGD008616 Red cell distribution width determination
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C2985280 BXGD018223 Blood Protein Measurement
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047088 Ursolic Acid 456.36
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein