Showing entry for Phosphoenolpyruvic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000942
Compound NamePhosphoenolpyruvic acid
Structure
FormulaC3H5O6P
InchiKeyDTBNBXWJWCWCIK-UHFFFAOYSA-N
SMILESOC(=O)C(=C)OP(O)(O)=O
InchiInChI=1S/C3H5O6P/c1-2(3(4)5)9-10(6,7)8/h1H2,(H,4,5)(H2,6,7,8)
IUPAC2-(phosphonooxy)prop-2-enoic acid
Molecular Weight168.04
Pubchem Id1005
Chembl IdCHEMBL1235228
Targets of Information Source
DrugBank DB01819
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P0AB91 BXGT007223 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive reviewed - aroG experimental -
P0A716 BXGT007084 2-dehydro-3-deoxyphosphooctonate aldolase reviewed - kdsA experimental -
P13929 BXGT007971 Beta-enolase reviewed Enzyme ENO3 experimental -
Q57265 BXGT015115 Capsule biosynthesis protein unreviewed - synC experimental -
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] reviewed Kinase PCK1 experimental -
O66496 BXGT004944 2-dehydro-3-deoxyphosphooctonate aldolase reviewed - kdsA experimental -
Q9WYH8 BXGT021987 Phospho-2-dehydro-3-deoxyheptonate aldolase reviewed - aroF experimental -
PDB PEP
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
O66496 BXGT004944 2-dehydro-3-deoxyphosphooctonate aldolase reviewed kdsA - - - - -
P0A715 BXGT007083 2-dehydro-3-deoxyphosphooctonate aldolase reviewed kdsA - - - - -
P32449 BXGT009639 Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited reviewed ARO4 - - - - -
P0AB91 BXGT007223 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive reviewed aroG - - - - -
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] reviewed PCK1 Kinase - - - -
P00924 BXGT005692 Enolase 1 reviewed ENO1 - - - - -
Q9WYH8 BXGT021987 Phospho-2-dehydro-3-deoxyheptonate aldolase reviewed aroF - - - - -
P11155 BXGT007659 Pyruvate, phosphate dikinase 1, chloroplastic reviewed PPDK1 - - - - -
Q9YEJ7 BXGT022374 Phospho-2-dehydro-3-deoxyheptonate aldolase unreviewed aroG - - - - -
Q57265 BXGT015115 Capsule biosynthesis protein unreviewed synC - - - - -
Q8U0A9 BXGT018865 2-dehydro-3-deoxyphosphoheptonate aldolase unreviewed PF1690 - - - - -
O66496 BXGT004944 2-dehydro-3-deoxyphosphooctonate aldolase reviewed kdsA - - - 40 -
O53512 BXGT004702 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG reviewed aroG - - - - -
Q16875 BXGT013686 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 reviewed PFKFB3 Kinase 8300 - - -
P9WPY5 BXGT012479 3-phosphoshikimate 1-carboxyvinyltransferase reviewed aroA - - - - -
P0A993 BXGT007176 Fructose-1,6-bisphosphatase class 1 reviewed fbp - - - - -
Q38BV6 BXGT014360 Enolase unreviewed Tb10.70.4740 - - - - -
P21642 BXGT008673 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial reviewed PCK2 - - - - -
P13035 BXGT007874 Aerobic glycerol-3-phosphate dehydrogenase reviewed glpD - - - - -
Q8R7R4 BXGT018691 Phosphoenolpyruvate-protein phosphotransferase unreviewed PtsA - - - - -
Q9JZ55 BXGT020855 2-dehydro-3-deoxyphosphooctonate aldolase reviewed kdsA - - - - -
Q16875 BXGT013686 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 reviewed PFKFB3 Kinase - - - -
Q8Y6T2 BXGT019089 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase unreviewed aroA - - - - -
P09104 BXGT006856 Gamma-enolase reviewed ENO2 Enzyme - - - -
Q3JP68 BXGT014456 2-dehydro-3-deoxyphosphooctonate aldolase unreviewed kdsA - - - - -
Q83E11 BXGT017502 3-phosphoshikimate 1-carboxyvinyltransferase reviewed aroA - - - - -
P07379 BXGT006617 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] reviewed Pck1 - - - - -
Q9K169 BXGT020867 Phospho-2-dehydro-3-deoxyheptonate aldolase unreviewed aroG - - - - -
P30615 BXGT009448 Pyruvate kinase 1 reviewed PYK1 - - - - -
P00512 BXGT005564 ATP-dependent 6-phosphofructokinase reviewed pfkA - - - 2100 -
P00512 BXGT005564 ATP-dependent 6-phosphofructokinase reviewed pfkA - - - 450 -
P00939 BXGT005695 Triosephosphate isomerase reviewed TPI1 - - - - -
A5TYT6 BXGT001351 Phosphoenolpyruvate carboxykinase [GTP] reviewed pckG - - - - -
A9WCM4 BXGT001809 Enolase reviewed eno - - - - -
P56060 BXGT011139 2-dehydro-3-deoxyphosphooctonate aldolase reviewed kdsA - - - - -
O69174 BXGT005042 Enolase reviewed eno - - - - -
Q8NNL5 BXGT018588 Phospho-2-dehydro-3-deoxyheptonate aldolase unreviewed Cgl2178 - - - - -
Q5N3P4 BXGT015576 Enolase reviewed eno - - - - -
P22221 BXGT008743 Pyruvate, phosphate dikinase, chloroplastic reviewed PPDK - - - - -
Q42736 BXGT014580 Pyruvate, phosphate dikinase, chloroplastic reviewed PPDK - - - - -
Q9I000 BXGT020684 Phospho-2-dehydro-3-deoxyheptonate aldolase unreviewed PA2843 - - - - -
P0A6P9 BXGT007065 Enolase reviewed eno - - - - -
G3XCJ9 BXGT003486 Phospho-2-dehydro-3-deoxyheptonate aldolase unreviewed phzC - - - - -
P9WP83 BXGT012442 Phosphoenolpyruvate guanylyltransferase reviewed fbiD - - - - -
P30613 BXGT009447 Pyruvate kinase PKLR reviewed PKLR Kinase - - - -
Binding DB 50366413
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT007865 Xaa-Pro dipeptidase reviewed Enzyme PEPD 8.5 - - -
reviewed BXGT007865 Xaa-Pro dipeptidase reviewed Enzyme PEPD 300 - - -
reviewed BXGT019400 Solute carrier organic anion transporter family member 2A1 reviewed Transporter SLCO2A1 13000000 - - -
CHEMBL CHEMBL1235228
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P12955 BXGT007865 Xaa-Pro dipeptidase reviewed Enzyme PEPD Ki '=' 300 nM
P12955 BXGT007865 Xaa-Pro dipeptidase reviewed Enzyme PEPD Ki '=' 8 nM
Q92959 BXGT019400 Solute carrier organic anion transporter family member 2A1 reviewed Transporter SLCO2A1 Ki '=' 13000000 nM
P12955 BXGT007865 Xaa-Pro dipeptidase reviewed Enzyme PEPD Ki' '=' 0 mM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00125 Rice Oryza sativa Cereals and cereal products
BXGF00205 Corn Zea mays Cereals and cereal products
BXGF03847 Thermopsis mollis Thermopsis mollis Others
BXGF04430 Crinum latifolium Crinum latifolium Medicinal Plant
BXGF05073 Alnus cordata Alnus cordata Human Edible Plant
BXGF05308 Aloe deltoideodonta Aloe deltoideodonta Others
BXGF05501 Bauhinia purpurea Bauhinia purpurea Medicinal Plant
BXGF05960 Leitneria floridana Leitneria floridana Others
BXGF06124 Notholaena aschenborniana Notholaena aschenborniana Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease