Showing entry for Solute carrier organic anion transporter family member 2A1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019400
Protein NameSolute carrier organic anion transporter family member 2A1
Uniport IdQ92959
GeneSLCO2A1
Gene Id6578
DomainKazal_2; OATP
Pfam PF07648   PF03137  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006869 lipid transport
Biological Process GO:0015732 prostaglandin transport
Biological Process GO:0043252 sodium-independent organic anion transport
molecular function GO:0005319 lipid transporter activity
molecular function GO:0015132 prostaglandin transmembrane transporter activity
molecular function GO:0015347 sodium-independent organic anion transmembrane transporter activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-5619095 Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2)
R-HSA-5619102 SLC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-879518 Transport of organic anions
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009080 BXGD000580 Clubbed Fingers Musculoskeletal Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0013221 BXGD000804 Drug toxicity Chemically-Induced Disorders
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017181 BXGD001103 Gastrointestinal Hemorrhage Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018418 BXGD001192 Gynecomastia Skin and Connective Tissue Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020492 BXGD001404 Hyperostosis Musculoskeletal Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027543 BXGD001997 Avascular necrosis of bone Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029411 BXGD002139 Osteoarthropathy, Primary Hypertrophic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030920 BXGD002263 Peptic Ulcer Digestive System Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036508 BXGD002623 Seborrheic dermatitis Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0041755 BXGD002933 Adverse reaction to drug Chemically-Induced Disorders
C0085660 BXGD003228 Aseptic necrosis Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0149651 BXGD003342 Clubbing
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0151971 BXGD003512 Primary ulcer of intestine Digestive System Diseases
C0152031 BXGD003524 Joint swelling Pathological Conditions, Signs and Symptoms
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0220810 BXGD004346 Congenital defects
C0235986 BXGD004799 Growth hormone excess Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0263417 BXGD005301 Cutis verticis gyrata
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0345408 BXGD007737 Hereditary clubbing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0346629 BXGD007831 Malignant neoplasm of large intestine Digestive System Diseases; Neoplasms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0523465 BXGD009209 Serum albumin measurement
C0544755 BXGD009310 Genu varum Musculoskeletal Diseases
C0575802 BXGD009521 Small hand
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1409412 BXGD013039 Periostosis
C1837315 BXGD014218 COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1857108 BXGD015677 Limitation of joint mobility
C1963077 BXGD016680 Bone Pain, CTCAE 3.0
C1963165 BXGD016685 Malabsorption, CTCAE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2674695 BXGD017254 Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2675481 BXGD017292 COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
C2677123 BXGD017364 COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
C2678439 BXGD017410 CRANIOOSTEOARTHROPATHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2751898 BXGD017749 Ventricular Fibrillation, Paroxysmal Familial, 1 Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C3280800 BXGD018866 HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 2
C3554460 BXGD019215 COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3839507 BXGD019774 Diminished ovarian reserve Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3887489 BXGD019879 Clubbing of toes
C3887513 BXGD019887 Avascular necrosis Pathological Conditions, Signs and Symptoms
C4021222 BXGD020584 Impaired temperature sensation Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4021611 BXGD020697 Abnormality of epiphysis morphology
C4021634 BXGD020709 Abnormality of bone marrow cell morphology
C4021741 BXGD020749 Abnormal cortical bone morphology
C4023397 BXGD021175 Abnormal hair quantity
C4023721 BXGD021252 Abnormal hair pattern
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4551679 BXGD023386 HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4553018 BXGD023532 Avascular Necrosis, CTCAE
C4554063 BXGD023559 Bone Pain, CTCAE 5.0
C4721411 BXGD023735 Osteolysis Musculoskeletal Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000942 Phosphoenolpyruvic acid 168.04
BXGC0001097 D-Glyceraldehyde 3-phosphate 170.06
BXGC0038275 Pyruvic Acid 88.02
BXGC0041324 Lactic Acid 90.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein