acompound

Showing entry for Norartocarpetin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0001737
Compound Name	Norartocarpetin
Structure
Formula	C15H10O6
InchiKey	ZSYPIPFQOQGYHH-UHFFFAOYSA-N
SMILES	OC1=CC(O)=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1
Inchi	InChI=1S/C15H10O6/c16-7-1-2-9(10(18)3-7)13-6-12(20)15-11(19)4-8(17)5-14(15)21-13/h1-6,16-19H
IUPAC	2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
Molecular Weight	286.24
Pubchem Id	5481970
Chembl Id	CHEMBL463145

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	-	1200	-	-
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	-	>3.00e+5	-	-
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	0.61	-	-	-
reviewed	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	82600	-	-	-
reviewed	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	-	60600	-	-
reviewed	BXGT005592	Pancreatic triacylglycerol lipase	reviewed		PNLIP	-	>70000	-	-
reviewed	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	-	14000	-	-
reviewed	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	-	>100000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	IC50	'='	14000	nM
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	Inhibition	'='	45	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	IC50	'>'	200000	nM
P56817	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	Ki	'='	82600	nM
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	IC50	'>'	100000	nM
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	IC50	'>'	70000	nM
A0A045ISB3	BXGT026108	Phosphotyrosine protein phosphatase	unreviewed	-	ptbB	IC50	'='	1202	nM
P14679	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	IC50	'='	23	nM
P56817	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	IC50	'='	60600	nM
P14679	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	Ratio IC50	'='	1900	-
Q05209	BXGT026141	Tyrosine-protein phosphatase non-receptor type 12	reviewed	-	PTPN12	IC50	'='	20940	nM
P9WIA1	BXGT012314	Probable low molecular weight protein-tyrosine-phosphatase	reviewed	-	ptpA	IC50	'='	11970	nM
A0A045ISB3	BXGT026108	Phosphotyrosine protein phosphatase	unreviewed	-	ptbB	IC50	'='	1200	nM
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	reviewed	-	PTPN22	IC50	'='	30290	nM
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	IC50	'='	5180	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00351	Jackfruit	Artocarpus heterophyllus	Fruits
BXGF00823	Fruits		Fruits
BXGF00947	Artocarpus dadah	Artocarpus dadah	Medicinal Plant
BXGF02214	Morus bombycis	Morus bombycis	Medicinal Plant
BXGF02852	Sophora flavescens	Sophora flavescens	Medicinal Plant
BXGF04607	Morus alba	Morus alba	Medicinal Plant
BXGF04967	Cudrania tricuspidata	Cudrania tricuspidata	Medicinal Plant
BXGF06007	Canthium berberidifolium	Canthium berberidifolium	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}