acompound

Showing entry for Tetramethylscutellarein

General Compound Information
BXGC Id	BXGC0001779
Compound Name	Tetramethylscutellarein
Structure
Formula	C19H18O6
InchiKey	URSUMOWUGDXZHU-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)C1=CC(=O)C2=C(OC)C(OC)=C(OC)C=C2O1
Inchi	InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(25-14)10-16(22-2)18(23-3)19(17)24-4/h5-10H,1-4H3
IUPAC	5,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Molecular Weight	342.34
Pubchem Id	96118
Chembl Id	CHEMBL75349

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50451668

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009016	Adenosine receptor A1	reviewed		Adora1	1288	-	-	-
reviewed	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	4467	-	-	-

CHEMBL

CHEMBL75349

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	26854	nM
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	25118	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	25118	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	3	%
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	28183	nM
P25099	BXGT009016	Adenosine receptor A1	reviewed	-	Adora1	pKi(uM)	'='	0	-
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	10000	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	29081	nM
P30543	BXGT009437	Adenosine receptor A2a	reviewed	-	Adora2a	pKi(uM)	-	-	-
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	pKi(uM)	'='	0	-
Q13148	BXGT013318	TAR DNA-binding protein 43	reviewed	-	TARDBP	Potency	-	3162	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	3981	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	25929	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	63095	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Activity	-	-	-
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	9200	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	-1	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	16360	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00038	Tea	Camellia sinensis	Teas
BXGF00056	Mandarin orange (Clementine, Tangerine)	Citrus reticulata	Fruits
BXGF00057	Sweet orange	Citrus sinensis	Fruits
BXGF00075	Black crowberry	Empetrum nigrum	Fruits
BXGF00125	Rice	Oryza sativa	Cereals and cereal products
BXGF00165	Common sage	Salvia officinalis	Herbs and Spices
BXGF00168	Winter savory	Satureja montana	Herbs and Spices
BXGF00818	Herbs and Spices		Herbs and Spices
BXGF00868	Clusia torresii	Clusia torresii	Others
BXGF00917	Rauvolfia tetraphylla	Rauvolfia tetraphylla	Medicinal Plant
BXGF01037	Ferula assa-foetida	Ferula assa-foetida	Medicinal Plant
BXGF01051	Callicarpa japonica	Callicarpa japonica	Medicinal Plant
BXGF01094	Asplenium nidus	Asplenium nidus	Human Edible Plant
BXGF01758	Cirsium helenioides	Cirsium helenioides	Others
BXGF01880	Stevia salicifolia	Stevia salicifolia	Others
BXGF01904	Orthosiphon aristatus	Orthosiphon aristatus	Medicinal Plant
BXGF01924	Handroanthus guayacan	Handroanthus guayacan	Others
BXGF02228	Pterocaulon rugosum	Pterocaulon rugosum	Others
BXGF02249	Ulmus laciniata	Ulmus laciniata	Medicinal Plant
BXGF02889	Salvia prionitis	Salvia prionitis	Medicinal Plant
BXGF02977	Jateorhiza palmata	Jateorhiza palmata	Medicinal Plant
BXGF03016	Ephedra lomatolepis	Ephedra lomatolepis	Others
BXGF03172	Picradeniopsis oppositifolia	Picradeniopsis oppositifolia	Others
BXGF03252	Tetraria capillaris	Tetraria capillaris	Others
BXGF03292	Maytenus guianensis	Maytenus guianensis	Others
BXGF03314	Saussurea triangulata	Saussurea triangulata	Others
BXGF03324	Phleum africanum	Phleum africanum	Others
BXGF03338	Lindera umbellata	Lindera umbellata	Medicinal Plant
BXGF03347	Stephania succifera	Stephania succifera	Medicinal Plant
BXGF03375	Clausena indica	Clausena indica	Human Edible Plant
BXGF03390	Gentiana olivieri	Gentiana olivieri	Medicinal Plant
BXGF03403	Vernonia serratuloides	Vernonia serratuloides	Others
BXGF03458	Ardisia macrocarpa	Ardisia macrocarpa	Human Edible Plant
BXGF03470	Chlorophytum malayense	Chlorophytum malayense	Medicinal Plant
BXGF03482	Gnetum cleistostachyum	Gnetum cleistostachyum	Others
BXGF03529	Pinus thunbergii	Pinus thunbergii	Medicinal Plant
BXGF03543	Teucrium alyssifolium	Teucrium alyssifolium	Others
BXGF03559	Orthosiphon stamineus	Orthosiphon stamineus	Medicinal Plant
BXGF03568	Senecio grandiflorus	Senecio grandiflorus	Others
BXGF03577	Zephyranthes carinata	Zephyranthes carinata	Medicinal Plant
BXGF03597	Angelica ursina	Angelica ursina	Medicinal Plant
BXGF03606	Pinus halepensis	Pinus halepensis	Medicinal Plant
BXGF03928	Celmisia petriei	Celmisia petriei	Others
BXGF04844	Primula veris	Primula veris	Medicinal Plant
BXGF05110	Euonymus maackii	Euonymus maackii	Others
BXGF05481	Populus tremula	Populus tremula	Medicinal Plant
BXGF05550	Morus yunnanensis	Morus yunnanensis	Others
BXGF05553	Astragalus inopinatus	Astragalus inopinatus	Others
BXGF05669	Marrubium velutinum	Marrubium velutinum	Medicinal Plant
BXGF05819	Citrus aurantium	Citrus aurantium	Medicinal Plant
BXGF05821	Nicotiana gossei	Nicotiana gossei	Medicinal Plant
BXGF06125	Senecio integerrimus	Senecio integerrimus	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}