Showing entry for Adenosine receptor A1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009016
Protein NameAdenosine receptor A1
Uniport IdP25099
GeneAdora1
Gene Id29290
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0050890 cognition
Biological Process GO:0050965 detection of temperature stimulus involved in sensory perception of pain
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0055089 fatty acid homeostasis
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0016042 lipid catabolic process
Biological Process GO:0002674 negative regulation of acute inflammatory response
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0045776 negative regulation of blood pressure
Biological Process GO:0097756 negative regulation of blood vessel diameter
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep
Biological Process GO:0042321 negative regulation of circadian sleep/wake cycle, sleep
Biological Process GO:0014050 negative regulation of glutamate secretion
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:0046888 negative regulation of hormone secretion
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0002686 negative regulation of leukocyte migration
Biological Process GO:0050995 negative regulation of lipid catabolic process
Biological Process GO:1900453 negative regulation of long-term synaptic depression
Biological Process GO:1900272 negative regulation of long-term synaptic potentiation
Biological Process GO:0070256 negative regulation of mucus secretion
Biological Process GO:0032900 negative regulation of neurotrophin production
Biological Process GO:0035814 negative regulation of renal sodium excretion
Biological Process GO:0032229 negative regulation of synaptic transmission, GABAergic
Biological Process GO:0051967 negative regulation of synaptic transmission, glutamatergic
Biological Process GO:0003085 negative regulation of systemic arterial blood pressure
Biological Process GO:0045777 positive regulation of blood pressure
Biological Process GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
Biological Process GO:0050996 positive regulation of lipid catabolic process
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0032244 positive regulation of nucleoside transport
Biological Process GO:0002793 positive regulation of peptide secretion
Biological Process GO:0043268 positive regulation of potassium ion transport
Biological Process GO:0035307 positive regulation of protein dephosphorylation
Biological Process GO:0003084 positive regulation of systemic arterial blood pressure
Biological Process GO:0006612 protein targeting to membrane
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0055117 regulation of cardiac muscle contraction
Biological Process GO:0003093 regulation of glomerular filtration
Biological Process GO:0002087 regulation of respiratory gaseous exchange by nervous system process
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0060087 relaxation of vascular associated smooth muscle
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0001659 temperature homeostasis
Biological Process GO:0070328 triglyceride homeostasis
molecular function GO:0031683 G-protein beta/gamma-subunit complex binding
molecular function GO:0001609 G protein-coupled adenosine receptor activity
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0031072 heat shock protein binding
molecular function GO:0032795 heterotrimeric G-protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0001883 purine nucleoside binding
cellular component GO:0032279 asymmetric synapse
cellular component GO:0030673 axolemma
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0044297 cell body
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0012505 endomembrane system
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0048786 presynaptic active zone
cellular component GO:0042734 presynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000204 Theophylline 180.16
BXGC0000205 Theobromine 180.16
BXGC0000340 Kaempferol 286.24
BXGC0000363 Galangin 270.24
BXGC0000964 6-Methylscutellarein 300.26
BXGC0001024 Cirsimaritin 314.29
BXGC0001166 Vitexin 6''-O-malonyl 2''-O-xyloside 432.38
BXGC0001409 7-Methylxanthine 166.14
BXGC0001420 Arborinine 285.29
BXGC0001502 Caffeine 194.19
BXGC0001779 Tetramethylscutellarein 342.34
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001994 Hyperin 464.38
BXGC0002018 Morin 302.24
BXGC0002046 Cassiachromone 232.23
BXGC0002071 Apigenin 270.24
BXGC0002081 Artocarpin 436.5
BXGC0002605 Adenosine 267.24
BXGC0002781 Flavonoids 224.25
BXGC0003048 Kaempferol 3-rhamno-glucoside 594.52
BXGC0003627 alpha-Linoleic acid 280.45
BXGC0003776 Flavones 222.24
BXGC0003804 4'-Methylgenkwanin 298.29
BXGC0005624 Genistein 270.24
BXGC0005667 Quercitrin 448.38
BXGC0005683 Quercetin 302.24
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0013612 Etofylline 224.09
BXGC0017352 Methylthioadenosine 297.09
BXGC0020835 5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol 251.1
BXGC0021235 Isoguanosine 283.09
BXGC0024313 2-(4-Hydroxy-3-Methoxyphenyl)-5-(3-Hydroxypropyl)-7-Methoxy-1-Benzofuran-3-Carbaldehyde 356.13
BXGC0024929 Visnagin 230.06
BXGC0024988 Nifedipine 346.12
BXGC0025572 2-(6-Cyclopentylamino-Purin-9-Yl)-5-Methylsulfanylmethyl-Tetrahydro-Furan-3,4-Diol 365.15
BXGC0025588 Chrysoeriol 7-neohesperidoside 608.17
BXGC0025833 L-Adenosine 267.1
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0027565 Deoxyadenosine 251.1
BXGC0028994 5'-O-Methyladenosine 281.11
BXGC0037967 Berchemol 4'-glucoside 538.21
BXGC0038499 Xanthine 152.03
BXGC0042546 5-Hydroxy-2-(4-Hydroxyphenyl)-7-Methoxy-2,3-Dihydrochromen-4-One 286.08
BXGC0043125 Taxifolin 304.06
BXGC0043126 Nicardipine 479.21
BXGC0043908 3-Methylxanthine 166.05
BXGC0044520 Massoniresinol 4'-glucoside 554.2
BXGC0046208 4'-O-Beta-D-Glucosyl-9-O-(6' '-Deoxysaccharosyl)Olivil 862.31
BXGC0046559 Paraxanthine 180.06
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0047923 Cirsimarin 476.13
BXGC0048407 3,5,7-Trimethoxyflavone 312.1
BXGC0049967 Tetramethylkaempferol 342.11
BXGC0052972 Aristeromycin 265.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein