Showing entry for Adenosine receptor A2a


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009437
Protein NameAdenosine receptor A2a
Uniport IdP30543
GeneAdora2a
Gene Id25369
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0048143 astrocyte activation
Biological Process GO:0042755 eating behavior
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0001973 G protein-coupled adenosine receptor signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0060080 inhibitory postsynaptic potential
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0046636 negative regulation of alpha-beta T cell activation
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0040013 negative regulation of locomotion
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0043116 negative regulation of vascular permeability
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Biological Process GO:0045938 positive regulation of circadian sleep/wake cycle, sleep
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0035815 positive regulation of renal sodium excretion
Biological Process GO:0032230 positive regulation of synaptic transmission, GABAergic
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0035810 positive regulation of urine volume
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0051924 regulation of calcium ion transport
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0014061 regulation of norepinephrine secretion
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0043279 response to alkaloid
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0031000 response to caffeine
Biological Process GO:0042493 response to drug
Biological Process GO:0007271 synaptic transmission, cholinergic
Biological Process GO:0001963 synaptic transmission, dopaminergic
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0042311 vasodilation
molecular function GO:0051393 alpha-actinin binding
molecular function GO:0019899 enzyme binding
molecular function GO:0001609 G protein-coupled adenosine receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0031802 type 5 metabotropic glutamate receptor binding
cellular component GO:0032279 asymmetric synapse
cellular component GO:0030673 axolemma
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0012505 endomembrane system
cellular component GO:0000139 Golgi membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0048786 presynaptic active zone
cellular component GO:0042734 presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000204 Theophylline 180.16
BXGC0000205 Theobromine 180.16
BXGC0000363 Galangin 270.24
BXGC0000964 6-Methylscutellarein 300.26
BXGC0001024 Cirsimaritin 314.29
BXGC0001409 7-Methylxanthine 166.14
BXGC0001420 Arborinine 285.29
BXGC0001502 Caffeine 194.19
BXGC0001779 Tetramethylscutellarein 342.34
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0002081 Artocarpin 436.5
BXGC0002605 Adenosine 267.24
BXGC0002781 Flavonoids 224.25
BXGC0003776 Flavones 222.24
BXGC0003804 4'-Methylgenkwanin 298.29
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0017352 Methylthioadenosine 297.09
BXGC0020835 5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol 251.1
BXGC0021235 Isoguanosine 283.09
BXGC0024261 Adenosine Phosphate 347.06
BXGC0024929 Visnagin 230.06
BXGC0024988 Nifedipine 346.12
BXGC0025572 2-(6-Cyclopentylamino-Purin-9-Yl)-5-Methylsulfanylmethyl-Tetrahydro-Furan-3,4-Diol 365.15
BXGC0025833 L-Adenosine 267.1
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0027565 Deoxyadenosine 251.1
BXGC0028994 5'-O-Methyladenosine 281.11
BXGC0033276 N6-(4-Hydroxybenzyl)Adenine Riboside 373.14
BXGC0036738 Bis(4-Hydroxybenzyl)Sulfide 246.07
BXGC0037967 Berchemol 4'-glucoside 538.21
BXGC0038499 Xanthine 152.03
BXGC0042546 5-Hydroxy-2-(4-Hydroxyphenyl)-7-Methoxy-2,3-Dihydrochromen-4-One 286.08
BXGC0043125 Taxifolin 304.06
BXGC0043126 Nicardipine 479.21
BXGC0043908 3-Methylxanthine 166.05
BXGC0044520 Massoniresinol 4'-glucoside 554.2
BXGC0046208 4'-O-Beta-D-Glucosyl-9-O-(6' '-Deoxysaccharosyl)Olivil 862.31
BXGC0046559 Paraxanthine 180.06
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0048407 3,5,7-Trimethoxyflavone 312.1
BXGC0049967 Tetramethylkaempferol 342.11
BXGC0052972 Aristeromycin 265.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein