Showing entry for Guanidino acetic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003343
Compound NameGuanidino acetic acid
Structure
FormulaC3H7N3O2
InchiKeyBPMFZUMJYQTVII-UHFFFAOYSA-N
SMILESNC(=N)NCC(O)=O
InchiInChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)
IUPAC2-carbamimidamidoacetic acid
Molecular Weight117.11
Pubchem Id763
Chembl IdCHEMBL281593
Targets of Information Source
DrugBank DB02751
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q14353 BXGT013463 Guanidinoacetate N-methyltransferase reviewed - GAMT experimental -
PDB NMG
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P10868 BXGT007626 Guanidinoacetate N-methyltransferase reviewed Gamt - - - - -
Binding DB 50021601
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 1500000 - - -
CHEMBL CHEMBL281593
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q15661 BXGT013588 Tryptase alpha/beta-1 reviewed - TPSAB1 Inhibition '=' -3 %
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 Ki '=' 1500000 nM
Q9ES14 BXGT020314 Gamma-aminobutyric acid receptor subunit epsilon reviewed - Gabre IC50 '=' 2100 nM
Q91ZM7 BXGT019327 GABA theta subunit unreviewed - Gabrq IC50 '=' 2100 nM
P63138 BXGT011502 Gamma-aminobutyric acid receptor subunit beta-2 reviewed - Gabrb2 IC50 '=' 2100 nM
P63079 BXGT011491 Gamma-aminobutyric acid receptor subunit beta-3 reviewed - Gabrb3 IC50 '=' 2100 nM
P62813 BXGT011460 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed - Gabra1 IC50 '=' 2100 nM
P30191 BXGT009410 Gamma-aminobutyric acid receptor subunit alpha-6 reviewed - Gabra6 IC50 '=' 2100 nM
P28473 BXGT009261 Gamma-aminobutyric acid receptor subunit gamma-3 reviewed - Gabrg3 IC50 '=' 2100 nM
P28471 BXGT009259 Gamma-aminobutyric acid receptor subunit alpha-4 reviewed - Gabra4 IC50 '=' 2100 nM
P23576 BXGT008885 Gamma-aminobutyric acid receptor subunit alpha-2 reviewed - Gabra2 IC50 '=' 2100 nM
P23574 BXGT008884 Gamma-aminobutyric acid receptor subunit gamma-1 reviewed - Gabrg1 IC50 '=' 2100 nM
P20236 BXGT008551 Gamma-aminobutyric acid receptor subunit alpha-3 reviewed - Gabra3 IC50 '=' 2100 nM
P19969 BXGT008536 Gamma-aminobutyric acid receptor subunit alpha-5 reviewed - Gabra5 IC50 '=' 2100 nM
P18508 BXGT008412 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed - Gabrg2 IC50 '=' 2100 nM
P18506 BXGT008410 Gamma-aminobutyric acid receptor subunit delta reviewed - Gabrd IC50 '=' 2100 nM
P15431 BXGT008122 Gamma-aminobutyric acid receptor subunit beta-1 reviewed - Gabrb1 IC50 '=' 2100 nM
O09028 BXGT004049 Gamma-aminobutyric acid receptor subunit pi reviewed - Gabrp IC50 '=' 2100 nM
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 pKi '=' 0 mM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00076 Loquat Eriobotrya japonica Fruits
BXGF00105 Apple Malus pumila Fruits
BXGF00148 Almond Prunus dulcis Nuts
BXGF01848 Pyrus pyraster Pyrus pyraster Medicinal Plant
BXGF02094 Astragalus oxyphysus Astragalus oxyphysus Others
BXGF02497 Hydrodictyon reticulatum Hydrodictyon reticulatum Human Edible Plant
BXGF02801 Senecio candollei Senecio candollei Others
BXGF02849 Polyscias scutellaria Polyscias scutellaria Medicinal Plant
BXGF02871 Centaurea glastifolia Centaurea glastifolia Others
BXGF02902 Grindelia havardii Grindelia havardii Others
BXGF02918 Nephelium maingayi Nephelium maingayi Human Edible Plant
BXGF02934 Galanthus nivalis Galanthus nivalis Medicinal Plant
BXGF02954 Euphorbia armena Euphorbia armena Others
BXGF06109 Cuscuta reflexa Cuscuta reflexa Medicinal Plant
BXGF06113 Plantago depressa Plantago depressa Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease