Showing entry for Tryptase alpha/beta-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013588
Protein NameTryptase alpha/beta-1
Uniport IdQ15661
GeneTPSAB1
Gene Id7177
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006952 defense response
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0006508 proteolysis
molecular function GO:0042802 identical protein binding
molecular function GO:0004252 serine-type endopeptidase activity
molecular function GO:0008236 serine-type peptidase activity
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
R-HSA-1592389 Activation of Matrix Metalloproteinases
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0009782 BXGD000631 Connective Tissue Diseases Skin and Connective Tissue Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011616 BXGD000739 Contact Dermatitis Skin and Connective Tissue Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0016382 BXGD001054 Flushing Pathological Conditions, Signs and Symptoms
C0019100 BXGD001283 Severe Dengue Infections
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024899 BXGD001812 Mastocytosis Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0162351 BXGD003938 Contact hypersensitivity Skin and Connective Tissue Diseases
C0376300 BXGD007987 Dengue Shock Syndrome Infections
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C4280806 BXGD022409 Calcium oxalate kidney stones
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001619 4-(1-Guanidino)butyric acid 145.16
BXGC0001630 Arginine 174.2
BXGC0003343 Guanidino acetic acid 117.11
BXGC0003705 Chloride 35.45
BXGC0005066 2R,3R-Butanediol 90.12
BXGC0006109 2-Aminoquinoline 144.17
BXGC0030612 tetraethylene glycol 194.12
BXGC0042188 1H-Benzimidazol-2-Amine 133.06
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein