Showing entry for Psidiolic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003765
Compound NamePsidiolic acid
Structure
FormulaC5H7NO3
InchiKeyODHCTXKNWHHXJC-VKHMYHEASA-N
SMILESOC(=O)[C@@H]1CCC(=O)N1
InchiInChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
IUPAC(2S)-5-oxopyrrolidine-2-carboxylic acid
Molecular Weight129.11
Pubchem Id7405
Chembl IdCHEMBL397976
Targets of Information Source
DrugBank DB03088
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P15692 BXGT008147 Vascular endothelial growth factor A reviewed Signaling VEGFA approved; investigational -
P04746 BXGT006256 Pancreatic alpha-amylase reviewed - AMY2A approved; investigational -
P0CG04 BXGT007464 Immunoglobulin lambda constant 1 reviewed - IGLC1 approved; investigational -
P01709 BXGT005779 Immunoglobulin lambda variable 2-8 reviewed - IGLV2-8 approved; investigational -
Q03403 BXGT012712 Trefoil factor 2 reviewed Signaling TFF2 approved; investigational -
P00091 BXGT005448 Cytochrome c2 reviewed - cycA approved; investigational -
Q9UKQ2 BXGT021748 Disintegrin and metalloproteinase domain-containing protein 28 reviewed Enzyme ADAM28 approved; investigational -
Q7SIE2 BXGT017122 Endo-1,4-beta-xylanase unreviewed - - approved; investigational -
O68601 BXGT005032 Copper-containing nitrite reductase unreviewed - nir approved; investigational -
Q701N4 BXGT016652 Keratin-associated protein 5-2 reviewed - KRTAP5-2 approved; investigational -
O43612 BXGT004605 Orexin reviewed - HCRT approved; investigational -
P80075 BXGT011876 C-C motif chemokine 8 reviewed Signaling CCL8 approved; investigational -
P00138 BXGT005462 Cytochrome c' reviewed - - approved; investigational -
P19961 BXGT008535 Alpha-amylase 2B reviewed - AMY2B approved; investigational -
PDB PCA
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P04746 BXGT006256 Pancreatic alpha-amylase reviewed AMY2A - - - - -
P0A7B5 BXGT007108 Glutamate 5-kinase reviewed proB - - - - -
Q7VXB1 BXGT017171 Putative exported protein unreviewed BP1891 - - - 300 -
Q7VXB3 BXGT017172 Putative exported protein unreviewed BP1887 - - - - -
Q9BVM4 BXGT020146 Gamma-glutamylaminecyclotransferase reviewed GGACT - - - - -
Q05929 BXGT012844 EDGP unreviewed EDGP1 - - - - -
P62694 BXGT011449 Exoglucanase 1 reviewed cbh1 - - - - -
H6UQI0 BXGT003610 Beta-lactamase unreviewed CTX-M-14 - - - - -
F1CYZ0 BXGT003208 Glucanase unreviewed cbh1 - - - - -
P01857 BXGT005796 Immunoglobulin heavy constant gamma 1 reviewed IGHG1 - - - - -
A0A088T0J9 BXGT000093 Glucanase unreviewed - - - - -
A0A158RFR1 BXGT000679 SM80.1 Vicilin unreviewed - - - - -
B4SL31 BXGT002143 Alkaline phosphatase unreviewed Smal_2208 - - - - -
P00138 BXGT005462 Cytochrome c' reviewed - - - - -
G0S3N2 BXGT003388 Exo-beta-1,3-glucanase-like protein unreviewed CTHT_0021860 - - - - -
E9G5J5 BXGT003175 Cellobiohydrolase CHBI unreviewed CEL7A - - - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed APP Enzyme modulator - - - -
G9NTY1 BXGT003571 Glucanase unreviewed TRIATDRAFT_88458 - - - - -
G0RVK1 BXGT003376 Glucanase unreviewed cel7a - - - - -
P13501 BXGT007917 C-C motif chemokine 5 reviewed CCL5 Signaling - - - -
A0A2R2JFU8 BXGT023481 pB1 unreviewed - - - - -
B6F0T7 BXGT002202 Jacalin-related lectin unreviewed PPL3 - - - - -
A0A2Z5V8U8 BXGT000795 Jacalin-related lectin unreviewed PPL3-b - - - - -
Q9RX25 BXGT023593 Pyrrolidone-carboxylate peptidase reviewed pcp - - - - -
A0A2Z5WLM1 BXGT000796 Galactose-specific lectin unreviewed AJLec - - - - -
C0HLB2 BXGT023689 Kunitz-type serine protease inhibitor PPTI (Pseudocerastes persicus trypsin inhibitor) (PPTI) reviewed - - - - -
Q9L5C7 BXGT021048 Beta-lactamase unreviewed blaCTX-M-14 - - - - -
Q99LC4 BXGT019989 Igh protein unreviewed Igh - - - - -
P96787 BXGT024108 Archaerhodopsin-3 reviewed aop3 - - - - -
P82358 BXGT024879 Gomesin reviewed - - - - -
I7AP60 BXGT025112 Beta-lactamase unreviewed CTX-M-27 - - - - -
P03420 BXGT006067 Fusion glycoprotein F0 reviewed F - - - - -
Q5BAS1 BXGT025306 Exo-1,4-beta-xylosidase xlnD reviewed xlnD - - - - -
W8P1L2 BXGT025603 Glucanase unreviewed - - - - -
P0DOX5 BXGT007515 Immunoglobulin gamma-1 heavy chain reviewed - - - - -
G5ZWD6 BXGT025900 TRAP-type C4-dicarboxylate transport system, periplasmic component unreviewed HIMB100_00003270 - - - - -
Q16769 BXGT013665 Glutaminyl-peptide cyclotransferase reviewed QPCT Enzyme - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL397976
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 405 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 5 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 35481 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 5309 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00085 Soy bean Glycine max Soy
BXGF00150 Guava Psidium guajava Fruits
BXGF00823 Fruits Fruits
BXGF00824 Green vegetables Vegetables
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01495 Pleione yunnanensis Pleione yunnanensis Others
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF02496 Pleione bulbocodioides Pleione bulbocodioides Others
BXGF02499 Cremastra appendiculata Cremastra appendiculata Medicinal Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04889 Pogostemon cablin Pogostemon cablin Medicinal Plant
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF05203 Chlamydomonas reinhardtii Chlamydomonas reinhardtii Others
BXGF05297 Isatis tinctoria Isatis tinctoria Medicinal Plant
BXGF06143 Persicaria tinctoria Persicaria tinctoria Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease