Showing entry for Trefoil factor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012712
Protein NameTrefoil factor 2
Uniport IdQ03403
GeneTFF2
Gene Id7032
DomainTrefoil
Pfam PF00088  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070098 chemokine-mediated signaling pathway
Biological Process GO:0030277 maintenance of gastrointestinal epithelium
Biological Process GO:0060455 negative regulation of gastric acid secretion
molecular function GO:0031723 CXCR4 chemokine receptor binding
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0014599 BXGD000939 Epithelial hyperplasia Pathological Conditions, Signs and Symptoms
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0017154 BXGD001097 Gastritis, Atrophic Digestive System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0019911 BXGD001352 Hookworm Infections Infections
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0032300 BXGD002346 Lobar Pneumonia Infections; Respiratory Tract Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038358 BXGD002748 Gastric ulcer Digestive System Diseases
C0085695 BXGD003243 Chronic gastritis Digestive System Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0155862 BXGD003827 Streptococcal pneumonia Infections; Respiratory Tract Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242488 BXGD005170 Acute Lung Injury Respiratory Tract Diseases
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0334037 BXGD006980 Intestinal metaplasia
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0348893 BXGD007883 Chronic superficial gastritis Digestive System Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0940937 BXGD011490 precancerous lesions
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3714514 BXGD019409 Infection Infections
C4038754 BXGD021859 Gastritis cystica profunda Digestive System Diseases
C4082937 BXGD022095 Necrotizing enterocolitis in fetus OR newborn Digestive System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003765 Psidiolic acid 129.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein