acompound

Showing entry for Genkwanin

General Compound Information
BXGC Id	BXGC0003813
Compound Name	Genkwanin
Structure
Formula	C16H12O5
InchiKey	JPMYFOBNRRGFNO-UHFFFAOYSA-N
SMILES	COC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(O)C=C1
Inchi	InChI=1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
IUPAC	5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
Molecular Weight	284.26
Pubchem Id	5281617
Chembl Id	CHEMBL210635

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50187658

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	-	8	-	-
reviewed	BXGT022265	Sialidase-2	reviewed	Enzyme	NEU2	-	>1000000	-	-
reviewed	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	>2340	-	-	-
reviewed	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	>2340	-	-	-

CHEMBL

CHEMBL210635

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P04745	BXGT006255	Alpha-amylase 1	reviewed	-	AMY1A	Inhibition	'='	17	%
Q965D6	BXGT019601	3-oxoacyl-acyl-carrier protein reductase	unreviewed	-	fabG	Activity	-	-	-
Q9Y3R4	BXGT022265	Sialidase-2	reviewed	Enzyme	NEU2	IC50	'>'	1000000	nM
Q965D5	BXGT019600	Enoyl-acyl-carrier protein reductase	unreviewed	-	fabI	Activity	-	-	-
Q9WKE8	BXGT021921	Reverse transcriptase	unreviewed	-	reverse	IC50	'>'	200	ug.mL-1
Q965D7	BXGT019602	Beta-hydroxyacyl-ACP dehydratase	unreviewed	-	fabZ	Activity	-	-	-
P04745	BXGT006255	Alpha-amylase 1	reviewed	-	AMY1A	IC50	-	-	-
P04798	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	Activity	'='	34	%
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	116	%
P04798	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	Ki	'>'	2340	nM
Q16678	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	Ki	'>'	2340	nM
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	IC50	'='	80	ug.mL-1
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	107	%
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	18	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00085	Soy bean	Glycine max	Soy
BXGF00111	Cornmint	Mentha arvensis	Herbs and Spices
BXGF00119	Sweet basil	Ocimum basilicum	Herbs and Spices
BXGF00159	Rosemary	Rosmarinus officinalis	Herbs and Spices
BXGF00165	Common sage	Salvia officinalis	Herbs and Spices
BXGF00168	Winter savory	Satureja montana	Herbs and Spices
BXGF00181	Dandelion	Taraxacum officinale	Herbs and Spices
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF01002	Acridocarpus vivy	Acridocarpus vivy	Others
BXGF01040	Euphorbia sancta	Euphorbia sancta	Others
BXGF01065	Artemisia capillaris	Artemisia capillaris	Medicinal Plant
BXGF01104	Garcinia cambogia	Garcinia cambogia	Medicinal Plant
BXGF01156	Senecio madagascariensis	Senecio madagascariensis	Human Edible Plant
BXGF01243	Asphodeline tenuior	Asphodeline tenuior	Others
BXGF01252	Petasites laevigatus	Petasites laevigatus	Medicinal Plant
BXGF01277	Glycyrrhiza triphylla	Glycyrrhiza triphylla	Others
BXGF01359	Daphne feddei	Daphne feddei	Others
BXGF01404	Sphaeranthus confertifolius	Sphaeranthus confertifolius	Others
BXGF01495	Pleione yunnanensis	Pleione yunnanensis	Others
BXGF01553	Iris hoogiana	Iris hoogiana	Others
BXGF01556	Ornithoglossum viride	Ornithoglossum viride	Others
BXGF01606	Schizanthus tricolor	Schizanthus tricolor	Others
BXGF01631	Anodendron affine	Anodendron affine	Medicinal Plant
BXGF01668	Taraxacum platycarpum	Taraxacum platycarpum	Medicinal Plant
BXGF01669	Hertia cheirifolia	Hertia cheirifolia	Others
BXGF01716	Mentha canadensis	Mentha canadensis	Medicinal Plant
BXGF01720	Cedrela salvadorensis	Cedrela salvadorensis	Others
BXGF01744	Xylosma longifolia	Xylosma longifolia	Medicinal Plant
BXGF01801	Bothriocline longipes	Bothriocline longipes	Medicinal Plant
BXGF01856	Aquilaria sinensis	Aquilaria sinensis	Medicinal Plant
BXGF01864	Baccharis trimera	Baccharis trimera	Medicinal Plant
BXGF01963	Hippeastrum papilio	Hippeastrum papilio	Others
BXGF02152	Taraxacum borealisinense	Taraxacum borealisinense	Others
BXGF02362	Prunus serrulata var. spontanea	Prunus serrulata var. spontanea	Medicinal Plant
BXGF02496	Pleione bulbocodioides	Pleione bulbocodioides	Others
BXGF02499	Cremastra appendiculata	Cremastra appendiculata	Medicinal Plant
BXGF02600	Berberis repens	Berberis repens	Others
BXGF02700	Prunus pseudocerasus	Prunus pseudocerasus	Medicinal Plant
BXGF02756	Schizonepeta tenuisfolia	Schizonepeta tenuisfolia	Others
BXGF02830	Amaranthus hybr	Amaranthus hybr	Medicinal Plant
BXGF02909	Eupatorium leucolepis	Eupatorium leucolepis	Others
BXGF03078	Chrysanthemum x morifolium	Chrysanthemum x morifolium	Medicinal Plant
BXGF03103	Cheilanthes fragrans	Cheilanthes fragrans	Medicinal Plant
BXGF03239	Fadogia agrestis	Fadogia agrestis	Medicinal Plant
BXGF03289	Ostrya carpinifolia	Ostrya carpinifolia	Medicinal Plant
BXGF03305	Aconitum variegatum	Aconitum variegatum	Medicinal Plant
BXGF03432	Chrysanthemum indicum	Chrysanthemum indicum	Medicinal Plant
BXGF03477	Stephania dielsiana	Stephania dielsiana	Medicinal Plant
BXGF03582	Sedum litoreum	Sedum litoreum	Others
BXGF03630	Taraxacum coreanum	Taraxacum coreanum	Others
BXGF03671	Leonurus japonicus	Leonurus japonicus	Medicinal Plant
BXGF03702	Solanum aculeatissimum	Solanum aculeatissimum	Medicinal Plant
BXGF03769	Artemisia iwayomogi	Artemisia iwayomogi	Others
BXGF04125	Leonurus sibiricus	Leonurus sibiricus	Medicinal Plant
BXGF04129	Diphasiastrum thyoides	Diphasiastrum thyoides	Others
BXGF04252	Wyethia mollis	Wyethia mollis	Medicinal Plant
BXGF04310	Taraxacum mongolicum	Taraxacum mongolicum	Medicinal Plant
BXGF04578	Metzgeria pubescens	Metzgeria pubescens	Others
BXGF04872	Glycyrrhiza glabra	Glycyrrhiza glabra	Medicinal Plant
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant
BXGF05011	Artemisia capillaries	Artemisia capillaries	Others
BXGF05088	Teucrium asiaticum	Teucrium asiaticum	Others
BXGF05161	Euphorbia myrsinites	Euphorbia myrsinites	Garden Plant
BXGF05201	Vicia amurensis	Vicia amurensis	Medicinal Plant
BXGF05235	Phlomoides rotata	Phlomoides rotata	Others
BXGF05404	Millettia ferruginea	Millettia ferruginea	Human Edible Plant
BXGF05436	Rubia tetragona	Rubia tetragona	Others
BXGF05557	Thermopsis dolichocarpa	Thermopsis dolichocarpa	Others
BXGF05586	Limnocharis flava	Limnocharis flava	Medicinal Plant
BXGF05608	Amaranthus hypochondriacus	Amaranthus hypochondriacus	Medicinal Plant
BXGF05657	Zanthoxylum fraxineum	Zanthoxylum fraxineum	Others
BXGF05683	Vaccinium ashei	Vaccinium ashei	Medicinal Plant
BXGF05806	Helicteres angustifolia	Helicteres angustifolia	Medicinal Plant
BXGF05858	Ormosia hosiei	Ormosia hosiei	Medicinal Plant
BXGF05907	Senecio viscosus	Senecio viscosus	Others
BXGF05992	Croton laccifer	Croton laccifer	Others
BXGF06092	Schizonepeta tenuifolia	Schizonepeta tenuifolia	Medicinal Plant
BXGF06202	Solidago spathulata	Solidago spathulata	Medicinal Plant
BXGF06250	Licaria chrysophylla	Licaria chrysophylla	Others
BXGF06282	Daphne genkwa	Daphne genkwa	Medicinal Plant
BXGF06308	Plagiomnium cuspidatum	Plagiomnium cuspidatum	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}