Showing entry for Alpha-amylase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006255
Protein NameAlpha-amylase 1
Uniport IdP04745
GeneAMY1A
Gene Id276;277;278
DomainAlpha-amylase; Alpha-amylase_C
Pfam PF00128   PF02806  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.4 Digestive system hsa04970 Salivary secretion
5. Organismal Systems 5.4 Digestive system hsa04970 Salivary secretion
5. Organismal Systems 5.4 Digestive system hsa04973 Carbohydrate digestion and absorption
5. Organismal Systems 5.4 Digestive system hsa04973 Carbohydrate digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
molecular function GO:0004556 alpha-amylase activity
molecular function GO:0103025 alpha-amylase activity (releasing maltohexaose)
molecular function GO:0046872 metal ion binding
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-189085 Digestion of dietary carbohydrate
R-HSA-8935690 Digestion
R-HSA-8963743 Digestion and absorption
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0014394 BXGD000914 Enuresis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0025048 BXGD001823 Meconium Aspiration Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Respiratory Tract Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0032002 BXGD002320 Pituitary Diseases Nervous System Diseases; Endocrine System Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0039494 BXGD002814 Temporomandibular Joint Disorders Musculoskeletal Diseases; Stomatognathic Diseases
C0085159 BXGD003133 Seasonal Affective Disorder Mental Disorders
C0085631 BXGD003214 Agitation Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0221773 BXGD004479 Hyperamylasemia Pathological Conditions, Signs and Symptoms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235013 BXGD004711 Hypervigilance Behavior and Behavior Mechanisms
C0236734 BXGD004823 Caffeine related disorders
C0242292 BXGD005146 McCune-Albright Syndrome Musculoskeletal Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0270327 BXGD006074 Bedwetting Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0270549 BXGD006079 Generalized Anxiety Disorder Mental Disorders
C0334299 BXGD007027 Carcinoid tumor no ICD-O subtype Neoplasms
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0403670 BXGD008303 Urinary incontinence of non-organic origin Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0700613 BXGD009896 Anxiety state Mental Disorders; Behavior and Behavior Mechanisms
C0730557 BXGD009965 Emotional abuse
C0860603 BXGD011236 Anxiety symptoms
C0871388 BXGD011314 social stress Behavior and Behavior Mechanisms
C1096155 BXGD011605 Macrophage Activation Syndrome Immune System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1279420 BXGD012122 Anxiety neurosis (finding) Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3825414 BXGD019695 Pain in children Pathological Conditions, Signs and Symptoms
C3887611 BXGD019904 Restlessness Behavior and Behavior Mechanisms
C4531100 BXGD023187 Negative affectivity
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000314 Isorhamnetin 316.26
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0000383 (S)-Naringenin 272.25
BXGC0000516 Diosmetin 300.26
BXGC0000764 L-Ascorbic acid 176.12
BXGC0001742 Eupafolin 316.26
BXGC0001778 Scutellarein 286.24
BXGC0001868 Catechin 290.27
BXGC0001899 Daidzein 254.24
BXGC0001962 Hesperetin 302.28
BXGC0002043 Acacetin 284.26
BXGC0002094 Rhamnetin 316.26
BXGC0002586 Calcium 40.08
BXGC0002690 alpha-Catechin 290.27
BXGC0003705 Chloride 35.45
BXGC0003804 4'-Methylgenkwanin 298.29
BXGC0003813 Genkwanin 284.26
BXGC0005620 beta-D-Glucopyranose 180.16
BXGC0005624 Genistein 270.24
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0005678 Quercetagetin 318.24
BXGC0005683 Quercetin 302.24
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0012913 Pentagalloyl Glucose 940.12
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0048389 Catechin 290.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein