acompound

Showing entry for 2,6-Diaminopurine

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0003981
Compound Name	2,6-Diaminopurine
Structure
Formula	C5H6N6
InchiKey	MSSXOMSJDRHRMC-UHFFFAOYSA-N
SMILES	NC1=NC2=C(NC=N2)C(N)=N1
Inchi	InChI=1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11)
IUPAC	7H-purine-2,6-diamine
Molecular Weight	150.14
Pubchem Id	30976
Chembl Id	CHEMBL388596

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q82Y41	BXGT017428	Cytidine and deoxycytidylate deaminase zinc-binding region	unreviewed	NE0047	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006445	Cyclin-dependent kinase 1	reviewed	Kinase	CDK1	-	>100000	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	>200000	-	-
reviewed	BXGT022246	Guanine deaminase	reviewed	Enzyme	GDA	1880	-	-	-
reviewed	BXGT004177	3-phosphoinositide-dependent protein kinase 1	reviewed	Kinase	PDPK1	-	50800	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	20596	nM
Q9Y2T3	BXGT022246	Guanine deaminase	reviewed	Enzyme	GDA	Inhibition	-	-	-
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	23109	nM
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed	-	IDH1	Potency	-	16360	nM
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	reviewed	Transcription factor	SMAD3	Potency	-	35481	nM
P06493	BXGT006445	Cyclin-dependent kinase 1	reviewed	Kinase	CDK1	IC50	'>'	100000	nM
Q9Y2T3	BXGT022246	Guanine deaminase	reviewed	Enzyme	GDA	Ki	'='	1880	nM
Q9WTT6	BXGT021931	Guanine deaminase	reviewed	-	Gda	Inhibition	-	-	-
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	18356	nM
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'>'	200000	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	6513	nM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	100000	nM
O15530	BXGT004177	3-phosphoinositide-dependent protein kinase 1	reviewed	Kinase	PDPK1	IC50	'='	50800	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	8199	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00197	Broad bean	Vicia faba	Pulses

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}