Showing entry for N-(2-Hydroxybenzoyl)glycine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0004709
Compound NameN-(2-Hydroxybenzoyl)glycine
Structure
FormulaC9H9NO4
InchiKeyONJSZLXSECQROL-UHFFFAOYSA-N
SMILESOC(=O)CNC(=O)C1=CC=CC=C1O
InchiInChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)
IUPAC2-[(2-hydroxyphenyl)formamido]acetic acid
Molecular Weight195.17
Pubchem Id10253
Chembl IdCHEMBL586
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50328021
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT019688 Egl nine homolog 2 reviewed EGLN2 - >1000000 - -
reviewed BXGT004543 Solute carrier family 22 member 6 reviewed Slc22a6 11000 - - -
reviewed BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 - 27000 - -
CHEMBL CHEMBL586
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 3162 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 5011 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
Q7ZJM1 BXGT017268 Integrase unreviewed - pol Inhibition '=' 28 %
Q7ZJM1 BXGT017268 Integrase unreviewed - pol Inhibition '=' 33 %
P14925 BXGT008070 Peptidylglycine alpha-amidating monooxygenase reviewed - Pam Ratio '=' 7 10'3/M/s
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 11000 nM
Q7ZJM1 BXGT017268 Integrase unreviewed - pol Inhibition '=' 25 %
Q96KS0 BXGT019688 Egl nine homolog 2 reviewed - EGLN2 IC50 '>' 1000000 nM
P14925 BXGT008070 Peptidylglycine alpha-amidating monooxygenase reviewed - Pam Km '=' 860000 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 3548 nM
P14925 BXGT008070 Peptidylglycine alpha-amidating monooxygenase reviewed - Pam Vmax(app) '=' 4 /s
P14925 BXGT008070 Peptidylglycine alpha-amidating monooxygenase reviewed - Pam Activity '=' 1 -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 3981 nM
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 IC50 '=' 27000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00815 Milk and milk products Milk and milk products
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease