acompound

Showing entry for 5,7-Dimethoxycoumarin

General Compound Information
BXGC Id	BXGC0005018
Compound Name	5,7-Dimethoxycoumarin
Structure
Formula	C11H10O4
InchiKey	NXJCRELRQHZBQA-UHFFFAOYSA-N
SMILES	COC1=CC(OC)=C2C=CC(=O)OC2=C1
Inchi	InChI=1S/C11H10O4/c1-13-7-5-9(14-2)8-3-4-11(12)15-10(8)6-7/h3-6H,1-2H3
IUPAC	5,7-dimethoxy-2H-chromen-2-one
Molecular Weight	206.19
Pubchem Id	2775
Chembl Id	CHEMBL481049

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

93217

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009127	Genome polyprotein	reviewed		-	-	58000	-	-

CHEMBL

CHEMBL481049

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	81	%
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	28183	nM
P25779	BXGT009067	Cruzipain	reviewed	-		Potency	'='	31622	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	35481	nM
Q9Y468	BXGT022270	Lethal(3)malignant brain tumor-like protein 1	reviewed	Epigenetic regulator	L3MBTL1	Potency	'='	39	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	25118	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	3162	nM
P06280	BXGT006433	Alpha-galactosidase A	reviewed	-	GLA	Potency	-	31622	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	15848	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	31622	nM
P06280	BXGT006433	Alpha-galactosidase A	reviewed	-	GLA	Potency	'='	14125	nM
Q92830	BXGT019379	Histone acetyltransferase KAT2A	reviewed	-	KAT2A	Potency	-	28183	nM
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	28183	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	105	%
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	28183	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	17782	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	20587	nM
P17405	BXGT008304	Sphingomyelin phosphodiesterase	reviewed	Enzyme	SMPD1	Potency	-	25118	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00053	Lime	Citrus aurantiifolia	Fruits
BXGF00054	Lemon	Citrus limon	Fruits
BXGF00206	Ginger	Zingiber officinale	Herbs and Spices
BXGF00811	Citrus		Fruits
BXGF00918	Urbanodendron verrucosum	Urbanodendron verrucosum	Others
BXGF00960	Adenia fruticosa	Adenia fruticosa	Others
BXGF00986	Centrosema haitense	Centrosema haitense	Others
BXGF01095	Bupleurum salicifolium	Bupleurum salicifolium	Others
BXGF01128	Aster ptarmicoides	Aster ptarmicoides	Medicinal Plant
BXGF01202	Osteospermum hyoseroides	Osteospermum hyoseroides	Others
BXGF01375	Pinus massoniana	Pinus massoniana	Medicinal Plant
BXGF01441	Hopea brevipetiolaris	Hopea brevipetiolaris	Others
BXGF01494	Sedum cepaea	Sedum cepaea	Medicinal Plant
BXGF01867	Rubus phoenicolasius	Rubus phoenicolasius	Medicinal Plant
BXGF01878	Lobelia chinensis	Lobelia chinensis	Medicinal Plant
BXGF02106	Citrus medica	Citrus medica	Medicinal Plant
BXGF02237	Citrus wilsonii	Citrus wilsonii	Medicinal Plant
BXGF02244	Galium album	Galium album	Medicinal Plant
BXGF02436	Bidens andicola	Bidens andicola	Others
BXGF02473	Echinochloa esculenta	Echinochloa esculenta	Human Edible Plant
BXGF02689	Ligularia hodgsonii	Ligularia hodgsonii	Medicinal Plant
BXGF03040	Lophozia floerkei	Lophozia floerkei	Others
BXGF03561	Saussurea pulchella	Saussurea pulchella	Medicinal Plant
BXGF04058	Bunium paucifolium	Bunium paucifolium	Others
BXGF04107	Plagiomnium undulatum	Plagiomnium undulatum	Others
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04935	Artemisia caucasica	Artemisia caucasica	Others
BXGF05122	Echinopepon bigelovii	Echinopepon bigelovii	Others
BXGF05206	Corydalis gigantea	Corydalis gigantea	Medicinal Plant
BXGF05373	Torricellia tiliifolia	Torricellia tiliifolia	Others
BXGF05697	Dysosma delavayi	Dysosma delavayi	Others
BXGF05882	Mosla japonica	Mosla japonica	Others
BXGF05977	Schisandra chinensis	Schisandra chinensis	Medicinal Plant
BXGF06132	Millettia rubiginosa	Millettia rubiginosa	Others
BXGF06232	Gomphostemma crinitum	Gomphostemma crinitum	Medicinal Plant
BXGF06267	Maharanga bicolor	Maharanga bicolor	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}