Showing entry for Lethal(3)malignant brain tumor-like protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022270
Protein NameLethal(3)malignant brain tumor-like protein 1
Uniport IdQ9Y468
GeneL3MBTL1
Gene Id26013
DomainMBT; zf-C2HC
Pfam PF02820   PF01530  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006325 chromatin organization
Biological Process GO:0030097 hemopoiesis
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0045652 regulation of megakaryocyte differentiation
Biological Process GO:0007088 regulation of mitotic nuclear division
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
molecular function GO:0003682 chromatin binding
molecular function GO:0042393 histone binding
molecular function GO:0042802 identical protein binding
molecular function GO:0035064 methylated histone binding
molecular function GO:0031493 nucleosomal histone binding
molecular function GO:0031491 nucleosome binding
molecular function GO:0032093 SAM domain binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0000785 chromatin
cellular component GO:0000793 condensed chromosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-212436 Generic Transcription Pathway
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-6804760 Regulation of TP53 Activity through Methylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0272170 BXGD006312 Shwachman syndrome
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0347272 BXGD007854 Benign neoplasm of large intestine Digestive System Diseases; Neoplasms
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000324 Isovitexin 432.38
BXGC0000369 Methyl gallate 184.15
BXGC0000436 Glycerol 92.09
BXGC0000505 Protocatechuic acid 154.12
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001167 Isoorientin 7-O-(6'''-O-(E)-feruloyl)glucoside 448.38
BXGC0001558 Papaveraldine 353.37
BXGC0001691 Questiomycin A 212.2
BXGC0001782 Sennoside B 862.74
BXGC0001843 Bergaptol 202.17
BXGC0002971 alpha-Lipoic acid 206.33
BXGC0003705 Chloride 35.45
BXGC0003852 Nigrin B 506.47
BXGC0004574 Eugenyl benzoate 268.31
BXGC0005018 5,7-Dimethoxycoumarin 206.19
BXGC0005254 Dibutyl phthalate 278.34
BXGC0005659 Arachidonic acid 304.47
BXGC0005667 Quercitrin 448.38
BXGC0005793 Baicalein 270.24
BXGC0005989 Auraptene 298.38
BXGC0006062 Isoorientin 448.38
BXGC0006107 alpha-Linolenic acid 278.43
BXGC0006306 Myricetin 318.24
BXGC0006308 Myricetin 3-rhamnoside 464.38
BXGC0006367 Mangiferin 422.34
BXGC0006732 3-Pentylpyridine 149.23
BXGC0007368 Luteolin 7-glucoside 448.38
BXGC0007533 Biotin 244.31
BXGC0008943 Kaempferol 3-robinobioside 594.52
BXGC0011280 Isothymonin 360.31
BXGC0011421 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone 166.17
BXGC0017393 Aucubin 346.13
BXGC0018287 Erythrosine 835.66
BXGC0018736 Benzamide 121.05
BXGC0019117 Tannic Acid 1700.17
BXGC0020847 Butyl 2-(2,4-Dichlorophenoxy)Acetate 276.03
BXGC0022009 (9R)-9-[(9R)-2-Carboxy-4-Hydroxy-10-Oxo-5-[(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracen-9-Yl]-4-Hydroxy-10-Oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracene-2-Carboxylic Acid 862.2
BXGC0022621 3-[(2S)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3,4-Dihydro-2H-Chromen-8-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 526.13
BXGC0022806 1-(5-Thiophen-2-Ylthiophen-2-Yl)Ethanone 208
BXGC0025200 2-Anilinonaphthalene-1,4-Dione 249.08
BXGC0025394 Scoulerine 327.15
BXGC0025876 Acetoside 624.21
BXGC0027249 Deoxyvasicinone 186.08
BXGC0028589 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 302.04
BXGC0030612 tetraethylene glycol 194.12
BXGC0031717 Purpurin 256.04
BXGC0034006 Fluoranthene 202.08
BXGC0034049 3-[(2S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Oxy-2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxychromen-4-One 434.08
BXGC0036263 Presenegenin 518.32
BXGC0037537 (9S,10R)-9,10-Dihydroxy-8,8-Dimethyl-9,10-Dihydropyrano[2,3-F]Chromen-2-One 262.08
BXGC0037599 Tanshinone Iia 294.13
BXGC0038066 Rescinnamine 634.29
BXGC0038083 Daphnorin 514.11
BXGC0038895 Emodic Acid 300.03
BXGC0039670 Nodakenin 408.14
BXGC0040528 2-Picolinic Acid 123.03
BXGC0041560 Thiram 239.99
BXGC0042046 Actinodaphnine 311.12
BXGC0042129 (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-Methylbut-3-En-2-Yloxy)Oxane-3,4,5-Triol 248.13
BXGC0042256 1,4-Bis[[(E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoyl]Oxy]-3,5-Dihydroxycyclohexane-1-Carboxylic Acid 516.13
BXGC0042281 Permethrin 390.08
BXGC0042365 (4R,12Bs)-7,9-Dimethoxy-3-Methyl-2,4,7A,13-Tetrahydro-1H-4,12-Methanobenzofuro[3,2-E]Isoquinoline 311.15
BXGC0042397 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-Methyl-2,3-Dihydrochromen-4-One 286.08
BXGC0042870 Piceatannol 244.07
BXGC0047405 Gamolenic Acid 278.22
BXGC0048801 Sid24823998 254.09
BXGC0049447 acetate 59.01
BXGC0050395 2-[(2S)-7-Oxo-2,3-Dihydrofuro[3,2-G]Chromen-2-Yl]Propan-2-Yl (E)-2-Methylbut-2-Enoate 328.13
BXGC0050651 Cryptotanshinone 296.14
BXGC0051982 Mannitol 182.08
BXGC0052374 Reserpine 608.27
BXGC0052393 [6-[2-(3,4-Dihydroxyphenyl)Ethoxy]-5-Hydroxy-2-(Hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxyoxan-3-Yl] (E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 624.21
BXGC0052798 5-Meo-Dmt 218.14
BXGC0053274 4-(2,3-Dihydroxy-3-Methylbutoxy)Furo[3,2-G]Chromen-7-One 304.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein