Showing entry for Biotin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0007533
Compound NameBiotin
Structure
FormulaC10H16N2O3S
InchiKeyYBJHBAHKTGYVGT-UHFFFAOYSA-N
SMILESOC(=O)CCCCC1SCC2NC(=O)NC12
InchiInChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)
IUPAC5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid
Molecular Weight244.31
Pubchem Id253
Chembl IdCHEMBL1527083
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1527083
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 112201 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 112201 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 100 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 31622 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 31622 nM
Q9Y468 BXGT022270 Lethal(3)malignant brain tumor-like protein 1 reviewed Epigenetic regulator L3MBTL1 Potency '=' 354 nM
P14618 BXGT008027 Pyruvate kinase PKM reviewed Kinase PKM Potency '=' 39810 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 12 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 10000 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 1778 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 1778 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 56 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 56 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 41 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 7943 nM
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 5623 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 22 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 2511 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 10 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 2818 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 11220 nM
Q13671 BXGT013391 Ras and Rab interactor 1 reviewed Enzyme modulator RIN1 IC50 '=' 528 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 IC50 '=' 528 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 2818 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 4 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 2818 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 20 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 20 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency - 14 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency - 14 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 580 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 794 nM
Q26513 BXGT013917 Glutathione-S-transferase unreviewed - gst-3 IC50 - 850 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00005 Allium (Onion) Allium Vegetables
BXGF00007 Leek Allium porrum Vegetables
BXGF00009 Chives Allium schoenoprasum Herbs and Spices
BXGF00013 Dill Anethum graveolens Herbs and Spices
BXGF00015 Wild celery Apium graveolens Herbs and Spices
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00021 Asparagus Asparagus officinalis Vegetables
BXGF00022 Oat Avena sativa Cereals and cereal products
BXGF00024 Brazil nut Bertholletia excelsa Nuts
BXGF00028 Swede Brassica napus Vegetables
BXGF00030 Common cabbage Brassica oleracea Vegetables
BXGF00031 Cauliflower Brassica oleracea var. botrytis Vegetables
BXGF00032 Brussel sprouts Brassica oleracea var. gemmifera Vegetables
BXGF00034 Broccoli Brassica oleracea var. italica Vegetables
BXGF00036 Turnip Brassica rapa var. rapa Herbs and Spices
BXGF00045 Chestnut Castanea Nuts
BXGF00049 Chicory Cichorium intybus Vegetables
BXGF00054 Lemon Citrus limon Fruits
BXGF00056 Mandarin orange (Clementine, Tangerine) Citrus reticulata Fruits
BXGF00057 Sweet orange Citrus sinensis Fruits
BXGF00065 Cucumber Cucumis sativus Gourds
BXGF00066 Cucurbita (Gourd) Cucurbita Gourds
BXGF00081 Fig Ficus carica Fruits
BXGF00083 Strawberry Fragaria X ananassa Fruits
BXGF00085 Soy bean Glycine max Soy
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00094 Common walnut Juglans regia Nuts
BXGF00095 Lettuce Lactuca sativa Vegetables
BXGF00098 Lentils Lens culinaris Pulses
BXGF00099 Garden cress Lepidium sativum Vegetables
BXGF00105 Apple Malus pumila Fruits
BXGF00125 Rice Oryza sativa Cereals and cereal products
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00130 Avocado Persea americana Vegetables
BXGF00131 Parsley Petroselinum crispum Herbs and Spices
BXGF00134 Common bean Phaseolus vulgaris Pulses
BXGF00141 Common pea Pisum sativum Pulses
BXGF00143 Prunus (Cherry, Plum) Prunus Fruits
BXGF00144 Apricot Prunus armeniaca Fruits
BXGF00148 Almond Prunus dulcis Nuts
BXGF00149 Peach Prunus persica Fruits
BXGF00152 Pear Pyrus communis Fruits
BXGF00155 Blackcurrant Ribes nigrum Fruits
BXGF00156 Redcurrant Ribes rubrum Fruits
BXGF00157 Gooseberry Ribes uva-crispa Fruits
BXGF00158 Watercress Rorippa nasturtium-aquaticum Herbs and Spices
BXGF00160 Rubus (Blackberry, Raspberry) Rubus Fruits
BXGF00166 Black elderberry Sambucus nigra Fruits
BXGF00169 Rye Secale cereale Cereals and cereal products
BXGF00170 Sesame Sesamum orientale Herbs and Spices
BXGF00171 Garden tomato Solanum lycopersicum Vegetables
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00178 Spinach Spinacia oleracea Vegetables
BXGF00182 Cocoa bean Theobroma cacao Cocoa and cocoa products
BXGF00186 Fenugreek Trigonella foenum-graecum Herbs and Spices
BXGF00187 Common wheat Triticum aestivum Cereals and cereal products
BXGF00194 Lingonberry Vaccinium vitis-idaea Fruits
BXGF00197 Broad bean Vicia faba Pulses
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00205 Corn Zea mays Cereals and cereal products
BXGF00208 Banana Musa acuminata Fruits
BXGF00210 Celeriac Apium graveolens var. rapaceum Vegetables
BXGF00230 Carrot Daucus carota ssp. sativus Vegetables
BXGF00239 Grapefruit Citrus X paradisi Fruits
BXGF00248 Beer Beverages
BXGF00249 Other bread Cereals and cereal products
BXGF00253 Pasta Cereals and cereal products
BXGF00254 Biscuit Cereals and cereal products
BXGF00302 Chervil Anthriscus cerefolium Herbs and Spices
BXGF00310 Coconut Cocos nucifera Fruits
BXGF00315 Cottonseed Gossypium Herbs and Spices
BXGF00330 Elderberry Sambucus Fruits
BXGF00338 Grape Vitis Fruits
BXGF00342 Haddock Melanogrammus aeglefinus Aquatic foods
BXGF00344 Hazelnut Corylus Nuts
BXGF00354 Jerusalem artichoke Helianthus tuberosus Vegetables
BXGF00357 Kale Brassica napus var. pabularia Vegetables
BXGF00400 French plantain Musa X paradisiaca Fruits
BXGF00454 Salmonidae (Salmon, Trout) Salmonidae Aquatic foods
BXGF00455 Cattle (Beef, Veal) Bos taurus Animal foods
BXGF00474 Gadus (Common cod) Gadus Aquatic foods
BXGF00475 Atlantic halibut Hippoglossus hippoglossus Aquatic foods
BXGF00478 Clupeinae (Herring, Sardine, Sprat) Clupeinae Aquatic foods
BXGF00486 Rabbit Leporidae Animal foods
BXGF00491 Shrimp Caridea Aquatic foods
BXGF00493 Flatfish Pleuronectiformes Aquatic foods
BXGF00494 Domestic pig (Piglet, Pork) Sus scrofa domestica Animal foods
BXGF00505 Common mushroom Agaricus bisporus Vegetables
BXGF00519 Wheat Triticum Cereals and cereal products
BXGF00532 Common dab Limanda limanda Aquatic foods
BXGF00534 Anatidae (Duck, Goose, Swan) Anatidae Animal foods
BXGF00537 Garfish Belone belone Aquatic foods
BXGF00539 Mountain hare Lepus timidus Animal foods
BXGF00541 Lemon sole Microstomus kitt Aquatic foods
BXGF00542 Clawed lobster Nephropidae Aquatic foods
BXGF00544 Scombridae (Bonito, Mackerel, Tuna) Scombridae Aquatic foods
BXGF00547 Norway lobster Nephrops norvegicus Aquatic foods
BXGF00550 True oyster Ostreidae Aquatic foods
BXGF00554 Pleuronectidae (Dab, Halibut, Plaice) Pleuronectidae Aquatic foods
BXGF00562 True sole Soleidae Aquatic foods
BXGF00565 Thunnus (Common tuna) Thunnus Aquatic foods
BXGF00566 Walnut Juglans Nuts
BXGF00574 Cheese Milk and milk products
BXGF00575 Milk (Cow) Milk and milk products
BXGF00576 Eggs Eggs
BXGF00577 Yogurt Milk and milk products
BXGF00595 Ymer Milk and milk products
BXGF00596 Other snack food Snack foods
BXGF00601 Marzipan Confectioneries
BXGF00602 Salad dressing Baking goods
BXGF00607 Cream Milk and milk products
BXGF00609 Sausage Dishes
BXGF00612 Pate Dishes
BXGF00615 Whey Milk and milk products
BXGF00618 Leavening agent Baking goods
BXGF00623 Milk (Human) Milk and milk products
BXGF00625 Baby food Baby foods
BXGF00632 Remoulade Baking goods
BXGF00642 Chocolate Cocoa and cocoa products
BXGF00643 Hot chocolate Cocoa and cocoa products
BXGF00644 Dried milk Milk and milk products
BXGF00645 Milk (Other mammals) Milk and milk products
BXGF00646 Kefir Milk and milk products
BXGF00647 Buttermilk Milk and milk products
BXGF00648 Other fermented milk Milk and milk products
BXGF00700 Semolina Cereals and cereal products
BXGF00711 Ketchup Baking goods
BXGF00720 Other fruit product Fruits
BXGF00758 Other bread product Cereals and cereal products
BXGF00761 Wheat bread Cereals and cereal products
BXGF00762 Rye bread Cereals and cereal products
BXGF00775 Vegetable juice Beverages
BXGF00802 Soft-necked garlic Allium sativum L. var. sativum Herbs and Spices
BXGF00809 Brassicas Vegetables
BXGF00810 Cereals and cereal products Cereals and cereal products
BXGF00817 Fishes Aquatic foods
BXGF00819 Pulses Pulses
BXGF00825 Root vegetables Vegetables
BXGF00835 Green bean Phaseolus vulgaris Pulses
BXGF00836 Saskatoon berry Amelanchier alnifolia Fruits
BXGF00838 Japanese pumpkin Cucurbita maxima Gourds
BXGF00839 White cabbage Brassica oleracea L. var. capitata L. f. alba DC. Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease