Showing entry for Epigallocatechin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0009548
Compound NameEpigallocatechin
Structure
FormulaC15H14O7
InchiKeyXMOCLSLCDHWDHP-IUODEOHRSA-N
SMILESO[C@@H]1CC2=C(O[C@@H]1C1=CC(O)=C(O)C(O)=C1)C=C(O)C=C2O
InchiInChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1
IUPAC(2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
Molecular Weight306.27
Pubchem Id72277
Chembl IdCHEMBL47386
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB EGT
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P09186 BXGT006867 Seed linoleate 9S-lipoxygenase-3 reviewed LOX1.3 - - - - -
Binding DB 50187665
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT007127 Ribonuclease HI reviewed rnhA - >20000 - -
reviewed BXGT007320 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI reviewed fabI - >100000 - -
reviewed BXGT007700 Glucose-6-phosphate 1-dehydrogenase reviewed ZWF1 - >1000000 - -
reviewed BXGT010923 6-phosphogluconate dehydrogenase, decarboxylating reviewed Enzyme PGD - >1000000 - -
reviewed BXGT006700 Aldo-keto reductase family 1 member B1 reviewed Akr1b1 - >30000 - -
reviewed BXGT010602 Xanthine dehydrogenase/oxidase reviewed Enzyme XDH - >100000 - -
CHEMBL CHEMBL47386
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P11412 BXGT007700 Glucose-6-phosphate 1-dehydrogenase reviewed - ZWF1 IC50 '>' 1000000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Intrinsic activity - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 '>' 30000 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Intrinsic activity - - -
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 3750 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ke '=' 250 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Inhibition '=' 19 %
P0AEK4 BXGT007320 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI reviewed - fabI IC50 '>' 100000 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 101 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Intrinsic activity - - -
P52209 BXGT010923 6-phosphogluconate dehydrogenase, decarboxylating reviewed Enzyme PGD IC50 '>' 1000000 nM
P0A7Y4 BXGT007127 Ribonuclease HI reviewed - rnhA IC50 '>' 20000 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ke '=' 1990 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ke '=' 300 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 17 nM
P10415 BXGT007567 Apoptosis regulator Bcl-2 reviewed Signaling BCL2 Ki '>' 100000 nM
P47989 BXGT010602 Xanthine dehydrogenase/oxidase reviewed Enzyme XDH IC50 '>' 100000 nM
P00374 BXGT005520 Dihydrofolate reductase reviewed Enzyme DHFR Activity - - -
Q965D7 BXGT019602 Beta-hydroxyacyl-ACP dehydratase unreviewed - fabZ Activity - - -
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Inhibition - - -
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Activity - - -
Q965D6 BXGT019601 3-oxoacyl-acyl-carrier protein reductase unreviewed - fabG Activity - - -
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 2000 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI IC50 '=' 7000 nM
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Kcat '=' 13 /s
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 96 %
P58335 BXGT011233 Anthrax toxin receptor 2 reviewed Receptor ANTXR2 IC50 '>' 300000 nM
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Kcat/Km '=' 53 /uM/s
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Km '=' 320 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00023 Star fruit Averrhoa carambola Fruits
BXGF00038 Tea Camellia sinensis Teas
BXGF00044 Pecan nut Carya illinoinensis Nuts
BXGF00062 Common hazelnut Corylus avellana Nuts
BXGF00083 Strawberry Fragaria X ananassa Fruits
BXGF00097 Sweet bay Laurus nobilis Herbs and Spices
BXGF00113 Peppermint Mentha X piperita Herbs and Spices
BXGF00114 Medlar Mespilus germanica Fruits
BXGF00134 Common bean Phaseolus vulgaris Pulses
BXGF00140 Pistachio Pistacia vera Nuts
BXGF00145 Sweet cherry Prunus avium Fruits
BXGF00148 Almond Prunus dulcis Nuts
BXGF00151 Pomegranate Punica granatum Fruits
BXGF00155 Blackcurrant Ribes nigrum Fruits
BXGF00156 Redcurrant Ribes rubrum Fruits
BXGF00160 Rubus (Blackberry, Raspberry) Rubus Fruits
BXGF00182 Cocoa bean Theobroma cacao Cocoa and cocoa products
BXGF00183 Common thyme Thymus vulgaris Herbs and Spices
BXGF00193 Bilberry Vaccinium myrtillus Fruits
BXGF00194 Lingonberry Vaccinium vitis-idaea Fruits
BXGF00197 Broad bean Vicia faba Pulses
BXGF00199 Gram bean Vigna mungo Pulses
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00208 Banana Musa acuminata Fruits
BXGF00315 Cottonseed Gossypium Herbs and Spices
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00432 Sesbania flower Sesbania bispinosa Vegetables
BXGF00503 Rowal Pangium edule Herbs and Spices
BXGF00570 Grape wine Beverages
BXGF00729 Shea tree Vitellaria paradoxa Herbs and Spices
BXGF00787 Yellow pond-lily Nuphar lutea Herbs and Spices
BXGF00804 Chinese bayberry Myrica rubra Fruits
BXGF00834 Yellow wax bean Phaseolus vulgaris Pulses
BXGF00835 Green bean Phaseolus vulgaris Pulses
BXGF00878 Lespedeza bicolor Lespedeza bicolor Medicinal Plant
BXGF00924 Phoenix loureiroi Phoenix loureiroi Medicinal Plant
BXGF00968 Thalictrum longistylum Thalictrum longistylum Medicinal Plant
BXGF01043 Acanthospermum glabratum Acanthospermum glabratum Medicinal Plant
BXGF01051 Callicarpa japonica Callicarpa japonica Medicinal Plant
BXGF01061 Avrainvillea longicaulis Avrainvillea longicaulis Others
BXGF01083 Elymus repens Elymus repens Medicinal Plant
BXGF01142 Arum alpinum Arum alpinum Others
BXGF01167 Tripterygium hypoglaucum Tripterygium hypoglaucum Others
BXGF01181 Atylosia trinervia Atylosia trinervia Others
BXGF01196 Elaeagnus commutata Elaeagnus commutata Medicinal Plant
BXGF01208 Angelica lucida Angelica lucida Human Edible Plant
BXGF01219 Salvia parryi Salvia parryi Others
BXGF01229 Strophanthus kombe Strophanthus kombe Medicinal Plant
BXGF01263 Adenopeltis colliguaya Adenopeltis colliguaya Others
BXGF01271 Castanea vesca Castanea vesca Others
BXGF01272 Iris ensata Iris ensata Medicinal Plant
BXGF01283 Crataegus pinnatifida Crataegus pinnatifida Medicinal Plant
BXGF01372 Quercus mongolica Quercus mongolica Medicinal Plant
BXGF01380 Cneorum pulverulentum Cneorum pulverulentum Medicinal Plant
BXGF01446 Perityle vaseyi Perityle vaseyi Others
BXGF01516 Petasites georgicus Petasites georgicus Others
BXGF01566 Pedicularis condensata Pedicularis condensata Others
BXGF01597 Senegalia catechu Senegalia catechu Medicinal Plant
BXGF01599 Helichrysum cephaloideum Helichrysum cephaloideum Medicinal Plant
BXGF01605 Palafoxia rosea Palafoxia rosea Others
BXGF01624 Acacia pachyphloia Acacia pachyphloia Others
BXGF01626 Nerine bowdenii Nerine bowdenii Others
BXGF01630 Cotula cinerea Cotula cinerea Medicinal Plant
BXGF01643 Chrozophora obliqua Chrozophora obliqua Medicinal Plant
BXGF01684 Hemionitis japonica Hemionitis japonica Others
BXGF01706 Daphniphyllum paxianum Daphniphyllum paxianum Others
BXGF01717 Senecio flavus Senecio flavus Medicinal Plant
BXGF01749 Salvia coulteri Salvia coulteri Others
BXGF01793 Sedum obtuso-lineare Sedum obtuso-lineare Others
BXGF01855 Porella swartziana Porella swartziana Others
BXGF01890 Trollius chinensis Trollius chinensis Medicinal Plant
BXGF01933 Piptocarpha oblonga Piptocarpha oblonga Others
BXGF01948 Meconopsis napaulensis Meconopsis napaulensis Medicinal Plant
BXGF01968 Rheum webbianum Rheum webbianum Medicinal Plant
BXGF01999 Mascarenhasia arborescens Mascarenhasia arborescens Others
BXGF02029 Eucalyptus flocktoniae Eucalyptus flocktoniae Others
BXGF02044 Chrysothamnus parryi Chrysothamnus parryi Others
BXGF02053 Hypericum balearicum Hypericum balearicum Others
BXGF02057 Kummerowia striata Kummerowia striata Medicinal Plant
BXGF02112 Thymbra spicata Thymbra spicata Medicinal Plant
BXGF02135 Phoebe formosana Phoebe formosana Others
BXGF02153 Sida cordifolia Sida cordifolia Medicinal Plant
BXGF02199 Bryum argenteum Bryum argenteum Medicinal Plant
BXGF02204 Apocynum venetum Apocynum venetum Medicinal Plant
BXGF02258 Millettia conraui Millettia conraui Medicinal Plant
BXGF02278 Centaurea seridis Centaurea seridis Others
BXGF02303 Centipeda cunninghami Centipeda cunninghami Others
BXGF02309 Flindersia brayleyana Flindersia brayleyana Others
BXGF02322 Gardenia turgida Gardenia turgida Medicinal Plant
BXGF02335 Satureja cuneifolia Satureja cuneifolia Human Edible Plant
BXGF02341 Euphorbia amygdaloides Euphorbia amygdaloides Medicinal Plant
BXGF02358 Consolida ajacis Consolida ajacis Medicinal Plant
BXGF02380 Entada phaseoloides Entada phaseoloides Medicinal Plant
BXGF02421 Hesperis matronalis Hesperis matronalis Medicinal Plant
BXGF02449 Jatropha macrorhiza Jatropha macrorhiza Others
BXGF02540 Jackiella javanica Jackiella javanica Medicinal Plant
BXGF02587 Rhus vulgaris Rhus vulgaris Human Edible Plant
BXGF02610 Cladrastis platycarpa Cladrastis platycarpa Others
BXGF02646 Eremanthus seidelii Eremanthus seidelii Others
BXGF02732 Senecio adenophyllus Senecio adenophyllus Others
BXGF02768 Lilium umbellatum Lilium umbellatum Others
BXGF02784 Artemisia rehan Artemisia rehan Others
BXGF02807 Elephantopus hirtiflorus Elephantopus hirtiflorus Others
BXGF02828 Nematolepis phebalioides Nematolepis phebalioides Others
BXGF02839 Solidago flexicaulis Solidago flexicaulis Human Edible Plant
BXGF02854 Ligularia cymbulifera Ligularia cymbulifera Others
BXGF02877 Coprosma areolata Coprosma areolata Medicinal Plant
BXGF02907 Oreopteris quelpaertensis Oreopteris quelpaertensis Others
BXGF02924 Lavandula dentata Lavandula dentata Medicinal Plant
BXGF02948 Viguiera linearis Viguiera linearis Others
BXGF02989 Turpinia ternata Turpinia ternata Medicinal Plant
BXGF03078 Chrysanthemum x morifolium Chrysanthemum x morifolium Medicinal Plant
BXGF03109 Cneoridium dumosum Cneoridium dumosum Others
BXGF03219 Hymenoxys insignis Hymenoxys insignis Others
BXGF03245 Pyrus ussuriensis Pyrus ussuriensis Medicinal Plant
BXGF03313 Magnolia montana Magnolia montana Medicinal Plant
BXGF03361 Alyxia reinwardtii Alyxia reinwardtii Medicinal Plant
BXGF03362 Stereospermum cylindricum Stereospermum cylindricum Medicinal Plant
BXGF03370 Maytenus aquifolium Maytenus aquifolium Others
BXGF03398 Solanum nigrum Solanum nigrum Medicinal Plant
BXGF03411 Valeriana wolgensis Valeriana wolgensis Others
BXGF03459 Cyanostegia microphylla Cyanostegia microphylla Others
BXGF03461 Microtropis fokienensis Microtropis fokienensis Others
BXGF03473 Maytenus cuzcoina Maytenus cuzcoina Others
BXGF03484 Ranunculus sceleratus Ranunculus sceleratus Medicinal Plant
BXGF03504 Sterculia foetida Sterculia foetida Medicinal Plant
BXGF03548 Euphorbia leuconeura Euphorbia leuconeura Others
BXGF03623 Heracleum sphondylium Heracleum sphondylium Medicinal Plant
BXGF03658 Centaurea linifolia Centaurea linifolia Others
BXGF03666 Bituminaria bituminosa Bituminaria bituminosa Medicinal Plant
BXGF03726 Serratula inermis Serratula inermis Others
BXGF03804 Machilus macrantha Machilus macrantha Medicinal Plant
BXGF04062 Spatholobus suberectus Spatholobus suberectus Medicinal Plant
BXGF04140 Dalbergia stipulacea Dalbergia stipulacea Medicinal Plant
BXGF04255 Gmelina asiatica Gmelina asiatica Medicinal Plant
BXGF04392 Artemisia carvifolia Artemisia carvifolia Others
BXGF04493 Lycoris radiata Lycoris radiata Medicinal Plant
BXGF04556 Xyris pterygoblephara Xyris pterygoblephara Others
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04659 Phyllanthus emblica Phyllanthus emblica Medicinal Plant
BXGF04736 Capnoides sempervirens Capnoides sempervirens Others
BXGF04992 Cephalaria uralensis Cephalaria uralensis Others
BXGF05010 Morella rubra Morella rubra 0
BXGF05080 Jungermannia obovata Jungermannia obovata Others
BXGF05195 Limonium sinense Limonium sinense Others
BXGF05215 Geranium sylvaticum Geranium sylvaticum Others
BXGF05244 Elephantopus mollis Elephantopus mollis Medicinal Plant
BXGF05269 Hypericum perforatum Hypericum perforatum Medicinal Plant
BXGF05285 Aglaia formosana Aglaia formosana Others
BXGF05295 Gomortega keule Gomortega keule Human Edible Plant
BXGF05389 Limonium gmelinii Limonium gmelinii Medicinal Plant
BXGF05394 Turraeanthus mannii Turraeanthus mannii Others
BXGF05430 Coleus garckeanus Coleus garckeanus Others
BXGF05441 Haplophyllum ferganicum Haplophyllum ferganicum Others
BXGF05478 Callicarpa maingayi Callicarpa maingayi Others
BXGF05487 Crotalaria aegyptiaca Crotalaria aegyptiaca Others
BXGF05490 Solanum sisymbriifolium Solanum sisymbriifolium Medicinal Plant
BXGF05517 Quercus robur Quercus robur Medicinal Plant
BXGF05519 Gerbera piloselloides Gerbera piloselloides Medicinal Plant
BXGF05522 Solidago serotina Solidago serotina Others
BXGF05578 Aglaia laxiflora Aglaia laxiflora Human Edible Plant
BXGF05689 Artemisia klotzchiana Artemisia klotzchiana Others
BXGF05732 Mimusops caffra Mimusops caffra Human Edible Plant
BXGF05766 Dicoma capensis Dicoma capensis Medicinal Plant
BXGF05776 Picea mariana Picea mariana Medicinal Plant
BXGF05828 Viguiera oblongifolia Viguiera oblongifolia Others
BXGF05829 Acacia arabica Acacia arabica Medicinal Plant
BXGF05849 Salacia chinensis Salacia chinensis Medicinal Plant
BXGF05872 Digitalis isabelliana Digitalis isabelliana Others
BXGF05873 Scopolia hladnikiana Scopolia hladnikiana Others
BXGF05967 Veronica arvensis Veronica arvensis Medicinal Plant
BXGF06034 Viburnum urceolatum Viburnum urceolatum Others
BXGF06087 Sonchus ortunoi Sonchus ortunoi Others
BXGF06088 Euryops algoensis Euryops algoensis Others
BXGF06096 Artemisia schimperi Artemisia schimperi Others
BXGF06111 Pteris radiata Pteris radiata Others
BXGF06167 Sorbaria sorbifolia Sorbaria sorbifolia Medicinal Plant
BXGF06174 Styrax ferrugineus Styrax ferrugineus Medicinal Plant
BXGF06183 Adina sessilifolia Adina sessilifolia Others
BXGF06238 Gardenia jasminoides Gardenia jasminoides Medicinal Plant
BXGF06263 Litsea pungens Litsea pungens Medicinal Plant
BXGF06277 Vincetoxicum hirundinaria Vincetoxicum hirundinaria Medicinal Plant
BXGF06285 Merremia umbellata Merremia umbellata Medicinal Plant
BXGF06305 Isocoma pluriflora Isocoma pluriflora Others
BXGF06323 Euphorbia turczaninowii Euphorbia turczaninowii Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease