acompound

Showing entry for Tanshindiol C

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0012404
Compound Name	Tanshindiol C
Structure
Formula	C18H16O5
InchiKey	RTKDBIDPGKCZJS-KZULUSFZSA-N
SMILES	O[C@@H]1CCc2c([C@@]1(C)O)ccc1c2C(=O)C(=O)c2c1occ2C
Inchi	InChI=1S/C18H16O5/c1-8-7-23-17-10-3-5-11-9(4-6-12(19)18(11,2)22)14(10)16(21)15(20)13(8)17/h3,5,7,12,19,22H,4,6H2,1-2H3/t12-,18-/m1/s1
IUPAC	(6R,7R)-6,7-dihydroxy-1,6-dimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
Molecular Weight	312.1
Pubchem Id	126072
Chembl Id	CHEMBL3287734

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	-	550	-	-
reviewed	BXGT005135	Polycomb protein EED	reviewed		EED	194	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q15022	BXGT013523	Polycomb protein SUZ12	reviewed	Nucleic acid binding	SUZ12	Inhibition	-	-	-
O75530	BXGT005135	Polycomb protein EED	reviewed	-	EED	Inhibition	-	-	-
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	Inhibition	-	-	-
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	Inhibition	-	-	-
Q16576	BXGT013641	Histone-binding protein RBBP7	reviewed	-	RBBP7	Inhibition	-	-	-
Q09028	BXGT013025	Histone-binding protein RBBP4	reviewed	-	RBBP4	Inhibition	-	-	-
Q15022	BXGT013523	Polycomb protein SUZ12	reviewed	Nucleic acid binding	SUZ12	IC50	'='	550	nM
O75530	BXGT005135	Polycomb protein EED	reviewed	-	EED	IC50	'='	550	nM
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	IC50	'='	550	nM
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	Inhibition	'='	50	%
Q16576	BXGT013641	Histone-binding protein RBBP7	reviewed	-	RBBP7	Ki	'='	194	nM
Q09028	BXGT013025	Histone-binding protein RBBP4	reviewed	-	RBBP4	Ki	'='	194	nM
Q15022	BXGT013523	Polycomb protein SUZ12	reviewed	Nucleic acid binding	SUZ12	Ki	'='	194	nM
O75530	BXGT005135	Polycomb protein EED	reviewed	-	EED	Ki	'='	194	nM
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	reviewed	Epigenetic regulator	EZH2	Ki	'='	194	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00880	Stauntonia obovatifoliola	Stauntonia obovatifoliola	Others
BXGF01390	Delphinium cyphoplectrum	Delphinium cyphoplectrum	Others
BXGF03376	Notholaena dealbata	Notholaena dealbata	Others
BXGF03744	Artemisia siversiana	Artemisia siversiana	Others
BXGF03882	Uvaria klaineana	Uvaria klaineana	Medicinal Plant
BXGF03927	Viburnum sieboldi	Viburnum sieboldi	Medicinal Plant
BXGF04075	Amentotaxus yunnanensis	Amentotaxus yunnanensis	Medicinal Plant
BXGF04096	Vicia sativa	Vicia sativa	Medicinal Plant
BXGF04106	Salvia przewalskii	Salvia przewalskii	Medicinal Plant
BXGF04156	Euphorbia retusa	Euphorbia retusa	Others
BXGF04422	Camptothecium lutescens	Camptothecium lutescens	Others
BXGF04603	Dioscorea communis	Dioscorea communis	Medicinal Plant
BXGF05228	Deguelia hatschbachii	Deguelia hatschbachii	Others
BXGF05526	Salvia miltiorrhiza	Salvia miltiorrhiza	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}