acompound

Showing entry for (2Z)-2-[(4-Chlorophenyl)Methylidene]-1-Benzofuran-3-One

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0013952
Compound Name	(2Z)-2-[(4-Chlorophenyl)Methylidene]-1-Benzofuran-3-One
Structure
Formula	C15H9ClO2
InchiKey	JIWJNEVCSMZRGO-ZROIWOOFSA-N
SMILES	Clc1ccc(cc1)/C=C/1\Oc2c(C1=O)cccc2
Inchi	InChI=1S/C15H9ClO2/c16-11-7-5-10(6-8-11)9-14-15(17)12-3-1-2-4-13(12)18-14/h1-9H/b14-9-
IUPAC	(2Z)-2-[(4-chlorophenyl)methylidene]-1-benzofuran-3-one
Molecular Weight	256.03
Pubchem Id	5467625
Chembl Id	CHEMBL596254

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008644	Amine oxidase [flavin-containing] A	reviewed		MAOA	-	709	-	-
reviewed	BXGT009172	Amine oxidase [flavin-containing] B	reviewed		MAOB	-	305	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	IC50	'='	305	nM
Q8IXJ6	BXGT018362	NAD-dependent protein deacetylase sirtuin-2	reviewed	Epigenetic regulator	SIRT2	Inhibition	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	'='	709	nM
P10826	BXGT007622	Retinoic acid receptor beta	reviewed	Nuclear receptor	RARB	Inhibition	-	-	-
Q969S8	BXGT019613	Polyamine deacetylase HDAC10	reviewed	Epigenetic regulator	HDAC10	Inhibition	'='	13	%
Q9UKV0	BXGT021750	Histone deacetylase 9	reviewed	Epigenetic regulator	HDAC9	Inhibition	'='	13	%
P56524	BXGT011176	Histone deacetylase 4	reviewed	Epigenetic regulator	HDAC4	Inhibition	'='	13	%
Q96DB2	BXGT019639	Histone deacetylase 11	reviewed	Epigenetic regulator	HDAC11	Inhibition	'='	13	%
Q9BY41	BXGT020180	Histone deacetylase 8	reviewed	Epigenetic regulator	HDAC8	Inhibition	'='	13	%
Q8WUI4	BXGT018992	Histone deacetylase 7	reviewed	Epigenetic regulator	HDAC7	Inhibition	'='	13	%
Q9UQL6	BXGT021813	Histone deacetylase 5	reviewed	Epigenetic regulator	HDAC5	Inhibition	'='	13	%
Q92769	BXGT019370	Histone deacetylase 2	reviewed	Epigenetic regulator	HDAC2	Inhibition	'='	13	%
Q9UBN7	BXGT021658	Histone deacetylase 6	reviewed	Epigenetic regulator	HDAC6	Inhibition	'='	13	%
O15379	BXGT004159	Histone deacetylase 3	reviewed	Epigenetic regulator	HDAC3	Inhibition	'='	13	%
Q13547	BXGT013373	Histone deacetylase 1	reviewed	Epigenetic regulator	HDAC1	Inhibition	'='	13	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02978	Tetradium ruticarpum	Tetradium ruticarpum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}