acompound

Showing entry for Oleandomycin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0017489
Compound Name	Oleandomycin
Structure
Formula	C35H61NO12
InchiKey	RZPAKFUAFGMUPI-QESOVKLGSA-N
SMILES	CO[C@H]1C[C@H](O[C@@H]2[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@H](C(=O)[C@@]3(C[C@@H]([C@@H]([C@H]2C)O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)C)CO3)C)O[C@H]([C@@H]1O)C
Inchi	InChI=1S/C35H61NO12/c1-16-14-35(15-43-35)32(40)19(4)27(37)18(3)22(7)46-33(41)21(6)31(47-26-13-25(42-11)28(38)23(8)45-26)20(5)30(16)48-34-29(39)24(36(9)10)12-17(2)44-34/h16-31,34,37-39H,12-15H2,1-11H3/t16-,17+,18-,19+,20+,21+,22+,23-,24-,25-,26-,27-,28-,29
IUPAC	(3R,5S,6S,7R,8S,9R,12R,13R,14S,15R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-8-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5,7,9,12,13,15-hexamethyl-1,11-dioxaspiro[2.13]hexadecane-10,16-dione
Molecular Weight	687.42
Pubchem Id	72493
Chembl Id	CHEMBL606258

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed		UGT1A1	-	44000	-	-
reviewed	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed		UGT1A4	-	59000	-	-
reviewed	BXGT008468	UDP-glucuronosyltransferase 1-6	reviewed		UGT1A6	-	>3.00e+5	-	-
reviewed	BXGT008253	UDP-glucuronosyltransferase 2B7	reviewed		UGT2B7	-	272000	-	-
reviewed	BXGT009924	UDP-glucuronosyltransferase 2B10	reviewed		UGT2B10	-	>3.00e+5	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q53685	BXGT015002	Oleandomycin glycosyltransferase	reviewed	-	oleD	Activity	'='	700	nmol/min
P55085	BXGT011104	Proteinase-activated receptor 2	reviewed	G-protein coupled receptor	F2RL1	Inhibition	-	-	-
Q53685	BXGT015002	Oleandomycin glycosyltransferase	reviewed	-	oleD	Activity	'='	200	nmol/min
Q53685	BXGT015002	Oleandomycin glycosyltransferase	reviewed	-	oleD	Activity	'='	13	nmol/min
Q53685	BXGT015002	Oleandomycin glycosyltransferase	reviewed	-	oleD	Activity	'='	70	nmol/min
Q53685	BXGT015002	Oleandomycin glycosyltransferase	reviewed	-	oleD	Activity	'='	1487	nmol/min

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00363	Wild leek	Allium ampeloprasum	Vegetables
BXGF02558	Drimia altissima	Drimia altissima	Medicinal Plant
BXGF02782	Helenium amarum	Helenium amarum	Medicinal Plant
BXGF02991	Scutellaria viscidula	Scutellaria viscidula	Medicinal Plant
BXGF03209	Senecio retrorsus	Senecio retrorsus	Medicinal Plant
BXGF03695	Taxus wallichiana	Taxus wallichiana	Medicinal Plant
BXGF03769	Artemisia iwayomogi	Artemisia iwayomogi	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}