Showing entry for Proteinase-activated receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011104
Protein NameProteinase-activated receptor 2
Uniport IdP55085
GeneF2RL1
Gene Id2150
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.7 Sensory system hsa04750 Inflammatory mediator regulation of TRP channels
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05143 African trypanosomiasis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007596 blood coagulation
Biological Process GO:0045217 cell-cell junction maintenance
Biological Process GO:0090195 chemokine secretion
Biological Process GO:0051607 defense response to virus
Biological Process GO:0061028 establishment of endothelial barrier
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006954 inflammatory response
Biological Process GO:0045087 innate immune response
Biological Process GO:0032609 interferon-gamma production
Biological Process GO:0032613 interleukin-10 production
Biological Process GO:0032611 interleukin-1 beta production
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0070661 leukocyte proliferation
Biological Process GO:0097029 mature conventional dendritic cell differentiation
Biological Process GO:0090198 negative regulation of chemokine secretion
Biological Process GO:0046329 negative regulation of JNK cascade
Biological Process GO:0034140 negative regulation of toll-like receptor 3 signaling pathway
Biological Process GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
Biological Process GO:0042119 neutrophil activation
Biological Process GO:0030836 positive regulation of actin filament depolymerization
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0050921 positive regulation of chemotaxis
Biological Process GO:0002720 positive regulation of cytokine production involved in immune response
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0043311 positive regulation of eosinophil degranulation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0003104 positive regulation of glomerular filtration
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0002690 positive regulation of leukocyte chemotaxis
Biological Process GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium
Biological Process GO:0060100 positive regulation of phagocytosis, engulfment
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0050927 positive regulation of positive chemotaxis
Biological Process GO:0031274 positive regulation of pseudopodium assembly
Biological Process GO:1900135 positive regulation of renin secretion into blood stream
Biological Process GO:0035025 positive regulation of Rho protein signal transduction
Biological Process GO:0032930 positive regulation of superoxide anion generation
Biological Process GO:0034137 positive regulation of toll-like receptor 2 signaling pathway
Biological Process GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
Biological Process GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0030193 regulation of blood coagulation
Biological Process GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production
Biological Process GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0046328 regulation of JNK cascade
Biological Process GO:0002286 T cell activation involved in immune response
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0031681 G-protein beta-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0015057 thrombin-activated receptor activity
cellular component GO:0005769 early endosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0031143 pseudopodium
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001420 BXGD000051 Papillary adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004623 BXGD000282 Bacterial Infections Infections
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009326 BXGD000598 Collagen Diseases Skin and Connective Tissue Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010692 BXGD000686 Cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015302 BXGD000974 External exotoses Musculoskeletal Diseases
C0016059 BXGD001043 Fibrosis Pathological Conditions, Signs and Symptoms
C0017160 BXGD001099 Gastroenteritis Digestive System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017178 BXGD001102 Gastrointestinal Diseases Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018188 BXGD001178 Granuloma Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0018621 BXGD001210 Hay fever Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020517 BXGD001415 Hypersensitivity Immune System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022408 BXGD001544 Arthropathy Musculoskeletal Diseases
C0022577 BXGD001556 Keratoconjunctivitis, Vernal Eye Diseases; Immune System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031094 BXGD002281 Periodontal Pocket Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032300 BXGD002346 Lobar Pneumonia Infections; Respiratory Tract Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035435 BXGD002549 Rheumatism Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0036502 BXGD002621 Sebaceous Gland Diseases Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085129 BXGD003128 Bronchial Hyperreactivity Respiratory Tract Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085278 BXGD003150 Antiphospholipid Syndrome Immune System Diseases
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0149516 BXGD003324 Chronic sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151785 BXGD003474 Disease of mucous membrane Pathological Conditions, Signs and Symptoms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152171 BXGD003552 Idiopathic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C0153453 BXGD003648 Malignant tumor of extrahepatic bile duct Digestive System Diseases; Neoplasms
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155862 BXGD003827 Streptococcal pneumonia Infections; Respiratory Tract Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202236 BXGD004086 Triglycerides measurement
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0234245 BXGD004641 Visceral Pain Pathological Conditions, Signs and Symptoms
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0234252 BXGD004646 Mechanical pain Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238019 BXGD004857 Carcinoma of extrahepatic bile duct Digestive System Diseases; Neoplasms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263361 BXGD005292 Psoriasis vulgaris Skin and Connective Tissue Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0276138 BXGD006403 Viral myocarditis Infections; Cardiovascular Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0332840 BXGD006900 Amputated structure (morphologic abnormality) Wounds and Injuries
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0345964 BXGD007755 Adenoma of lung Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0347073 BXGD007847 Carcinoma in situ of mouth Neoplasms; Stomatognathic Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0596240 BXGD009638 Cancer Pain Pathological Conditions, Signs and Symptoms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699949 BXGD009872 airway disease Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0730321 BXGD009957 Punctate inner choroidopathy Eye Diseases
C0740277 BXGD009972 Bile duct carcinoma Digestive System Diseases; Neoplasms
C0747479 BXGD010170 Periodontal infection
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0856687 BXGD011106 Infection caused by Trichinella
C0876991 BXGD011323 Histiocytosis haematophagic
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948249 BXGD011521 Femoral artery occlusion Cardiovascular Diseases
C0948780 BXGD011554 Rhinosinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0948908 BXGD011564 Nephrotoxic serum nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1262048 BXGD011866 Glial scar
C1262211 BXGD011876 Diarrhoea predominant irritable bowel syndrome
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1333034 BXGD012582 Chronic Cancer Pain Pathological Conditions, Signs and Symptoms
C1334177 BXGD012684 Infiltrating Cervical Carcinoma
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1397307 BXGD012996 Cardiac fibrosis
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510885 BXGD013178 Angiogenic Switch
C1519346 BXGD013235 Skin Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1536148 BXGD013338 Chocolate cyst of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1855038 BXGD015452 Hepatocellular necrosis
C1859592 BXGD015912 ATRICHIA WITH PAPULAR LESIONS Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1956089 BXGD016615 Osteophyte Musculoskeletal Diseases
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3495798 BXGD019003 Periodontal inflammation
C3495801 BXGD019004 Granulomatosis with polyangiitis Respiratory Tract Diseases; Immune System Diseases; Cardiovascular Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3544205 BXGD019109 Ovarian clear cell carcinoma
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C4020969 BXGD020517 Inflammatory abnormality of the eye
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4554344 BXGD023564 IgE-mediated food allergy Immune System Diseases
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722099 BXGD023789 High grade glioma Neoplasms
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4744444 BXGD023941 Metastatic Lung Adenocarcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0017489 Oleandomycin 687.42
BXGC0040155 Triptolide 360.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein