acompound

Showing entry for Hydroxyproline

General Compound Information
BXGC Id	BXGC0025746
Compound Name	Hydroxyproline
Structure
Formula	C5H9NO3
InchiKey	PMMYEEVYMWASQN-DMTCNVIQSA-N
SMILES	O[C@H]1CN[C@@H](C1)C(=O)O
Inchi	InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
IUPAC	(2S,4R)-4-hydroxypyrrolidin-1-ium-2-carboxylate
Molecular Weight	131.06
Pubchem Id	5810
Chembl Id	CHEMBL352418

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

HYP

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P85065	BXGT012072	Lantibiotic 107891	reviewed		-	-	-	-	-
P09546	BXGT006905	Bifunctional protein PutA	reviewed	putA	-	-	-	-	-
Q4KGU2	BXGT014846	4-hydroxyproline 2-epimerase	reviewed	PFL_1412	-	-	-	-	-
B9JQV3	BXGT002332	4-hydroxyproline 2-epimerase	reviewed	Avi_0518	-	-	-	-	-
Q941C5	BXGT019549	CLAVATA3/ESR (CLE)-related protein 44	reviewed	CLE44	-	-	-	-	-
Q84W98	BXGT017570	CLAVATA3/ESR (CLE)-related protein 41	reviewed	CLE41	-	-	-	-	-
A0A1U7Q1Y9	BXGT023204	Bergofungin A	unreviewed		-	-	-	-	-
A8DP67	BXGT001678	Ribulose bisphosphate carboxylase large chain	unreviewed	rbcL	-	-	-	-	-
Q9P8C9	BXGT021315	Xylose isomerase	unreviewed	xylA	-	-	-	-	-
P02452	BXGT005878	Collagen alpha-1(I) chain	reviewed	COL1A1	-	-	-	-	-
A0A3B6UEF4	BXGT023322	Ribulose bisphosphate carboxylase large chain	unreviewed		-	-	-	-	-
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	reviewed	EPAS1	Transcription factor	-	-	-	-
A0A3S5WI22	BXGT023820	Conotoxin MoVIB	unreviewed		-	-	-	-	-
A0A384E137	BXGT023965	Nemertide alpha-1	unreviewed		-	-	-	-	-
P85421	BXGT012077	Alpha-amanitin proprotein	reviewed		-	-	-	-	-
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	reviewed	HIF1A	Transcription factor	-	-	-	-
P08123	BXGT024477	Collagen alpha-2(I) chain	reviewed	COL1A2	-	-	-	-	-
P05482	BXGT024844	Mu-conotoxin GIIIC	reviewed		-	-	-	-	-
A0A031WDE4	BXGT025861	Trans-4-hydroxy-L-proline dehydratase	reviewed	pflD	-	-	-	-	-
P0CU64	BXGT026039	Phalloidin proprotein [Cleaved into: Phalloidin]	reviewed		-	-	-	-	-

Binding DB

50357233

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT017247	Proton-coupled amino acid transporter 1	reviewed	Transporter	SLC36A1	9000000	-	-	-

CHEMBL

CHEMBL352418

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	reviewed	Enzyme	VHL	Activity	-	-	-
Q15758	BXGT013594	Neutral amino acid transporter B(0)	reviewed	Transporter	SLC1A5	IC50	'<'	2000000	nM
Q7Z2H8	BXGT017247	Proton-coupled amino acid transporter 1	reviewed	Transporter	SLC36A1	pKi	'='	0	mM
P97521	BXGT012209	Mitochondrial carnitine/acylcarnitine carrier protein	reviewed	-	Slc25a20	Experimental DPM	'='	5346	-
Q9GZT9	BXGT020425	Egl nine homolog 1	reviewed	-	EGLN1	Inhibition	-	-	-
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	3047000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	Inhibition	-	-	-
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	16000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	17200	nM
P63116	BXGT011501	Asc-type amino acid transporter 1	reviewed	-	Slc7a10	IC50	'>'	10000000	nM
Q7Z2H8	BXGT017247	Proton-coupled amino acid transporter 1	reviewed	Transporter	SLC36A1	Ki	'='	9000000	nM
P43007	BXGT010350	Neutral amino acid transporter A	reviewed	Transporter	SLC1A4	IC50	'='	188000	nM
Q15758	BXGT013594	Neutral amino acid transporter B(0)	reviewed	Transporter	SLC1A5	IC50	'='	3475000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	38900	nM
P43007	BXGT010350	Neutral amino acid transporter A	reviewed	Transporter	SLC1A4	IC50	'<'	2000000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	Inhibition	'>='	25	%
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	2989000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00979	Cistanche deserticola	Cistanche deserticola	Medicinal Plant
BXGF02526	Santalum album	Santalum album	Medicinal Plant
BXGF02965	Arabidopsis thaliana	Arabidopsis thaliana	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}