Showing entry for Neutral amino acid transporter A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010350
Protein NameNeutral amino acid transporter A
Uniport IdP43007
GeneSLC1A4
Gene Id6509
DomainSDF
Pfam PF00375  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006865 amino acid transport
Biological Process GO:0050890 cognition
Biological Process GO:0006868 glutamine transport
Biological Process GO:0034589 hydroxyproline transport
Biological Process GO:1904273 L-alanine import across plasma membrane
Biological Process GO:0015808 L-alanine transport
Biological Process GO:0140009 L-aspartate import across plasma membrane
Biological Process GO:0015811 L-cystine transport
Biological Process GO:1903812 L-serine import across plasma membrane
Biological Process GO:0015825 L-serine transport
Biological Process GO:0015824 proline transport
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0015826 threonine transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0005254 chloride channel activity
molecular function GO:0015180 L-alanine transmembrane transporter activity
molecular function GO:0015183 L-aspartate transmembrane transporter activity
molecular function GO:0015184 L-cystine transmembrane transporter activity
molecular function GO:0015186 L-glutamine transmembrane transporter activity
molecular function GO:0034590 L-hydroxyproline transmembrane transporter activity
molecular function GO:0015193 L-proline transmembrane transporter activity
molecular function GO:0015194 L-serine transmembrane transporter activity
molecular function GO:0015195 L-threonine transmembrane transporter activity
molecular function GO:0015293 symporter activity
cellular component GO:0009986 cell surface
cellular component GO:0005813 centrosome
cellular component GO:0030425 dendrite
cellular component GO:0070062 extracellular exosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005882 intermediate filament
cellular component GO:0042470 melanosome
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0022107 BXGD001530 Irritable Mood Behavior and Behavior Mechanisms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0034935 BXGD002497 Babinski Reflex
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037769 BXGD002701 West Syndrome Nervous System Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0268381 BXGD005922 Primary amyloidosis Neoplasms; Nutritional and Metabolic Diseases; Immune System Diseases
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426970 BXGD008598 Spastic Quadriplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0432072 BXGD008718 Dysmorphic features
C0523465 BXGD009209 Serum albumin measurement
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1850456 BXGD015146 Progressive microcephaly
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2599768 BXGD017147 Fractional shortening
C2677180 BXGD017366 Congenital microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2700617 BXGD017474 Irritation - emotion Behavior and Behavior Mechanisms
C3472608 BXGD018921 Micropapillary carcinoma
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887898 BXGD019926 Infantile Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4225254 BXGD022193 SPASTIC TETRAPLEGIA, THIN CORPUS CALLOSUM, AND PROGRESSIVE MICROCEPHALY
C4552810 BXGD023525 Irritability, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000279 L-Alanine 89.09
BXGC0000288 L-Proline 115.13
BXGC0000458 L-Asparagine 132.12
BXGC0012340 L-glutamine 146.14
BXGC0025746 Hydroxyproline 131.06
BXGC0028981 Serine 105.04
BXGC0030028 (D)-Serine 105.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein