acompound

Showing entry for Norarmepavine

General Compound Information
BXGC Id	BXGC0027312
Compound Name	Norarmepavine
Structure
Formula	C18H21NO3
InchiKey	NKBBUUNAVOMVER-INIZCTEOSA-N
SMILES	COc1cc2[C@@H](NCCc2cc1OC)Cc1ccc(cc1)O
Inchi	InChI=1S/C18H21NO3/c1-21-17-10-13-7-8-19-16(15(13)11-18(17)22-2)9-12-3-5-14(20)6-4-12/h3-6,10-11,16,19-20H,7-9H2,1-2H3/t16-/m0/s1
IUPAC	4-[[(1S)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]phenol
Molecular Weight	299.15
Pubchem Id	6999736
Chembl Id	CHEMBL453038

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50292465

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008936	Sodium-dependent dopamine transporter	reviewed		Slc6a3	-	37000	-	-

CHEMBL

CHEMBL453038

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	reviewed	G-protein coupled receptor	PTH1R	Potency	-	44668	nM
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	reviewed	Transcription factor	SMAD3	Potency	-	22387	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	16360	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	25118	nM
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	100000	nM
P23977	BXGT008936	Sodium-dependent dopamine transporter	reviewed	-	Slc6a3	IC50	'='	37000	nM
P00811	BXGT005666	Beta-lactamase	reviewed	-	ampC	Potency	'='	631	nM
O95149	BXGT005350	Snurportin-1	reviewed	-	SNUPN	Potency	-	125892	nM
Q14974	BXGT013516	Importin subunit beta-1	reviewed	Transporter	KPNB1	Potency	-	125892	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	4	nM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	112201	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	28183	nM
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	reviewed	-	GNAS	Potency	-	3548	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	16360	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Potency	-	70794	nM
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	44668	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	50118	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	8912	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	14581	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00132	Scarlet bean	Phaseolus coccineus	Pulses
BXGF00141	Common pea	Pisum sativum	Pulses
BXGF00142	Purslane	Portulaca oleracea	Herbs and Spices
BXGF01324	Albizia julibrissin	Albizia julibrissin	Medicinal Plant
BXGF04187	Cheilanthes mysurensis	Cheilanthes mysurensis	Others
BXGF05151	Myristica argentea	Myristica argentea	Medicinal Plant
BXGF05298	Lonchocarpus urucu	Lonchocarpus urucu	Others
BXGF05574	Artemisia arbuscula	Artemisia arbuscula	Medicinal Plant
BXGF05800	Mimosa pudica	Mimosa pudica	Medicinal Plant
BXGF06094	Aconitum fauriei	Aconitum fauriei	Others
BXGF06150	Citrus reshni	Citrus reshni	Human Edible Plant
BXGF06279	Dacrycarpus imbricatus	Dacrycarpus imbricatus	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}